Results 41 to 50 of about 60,360 (226)

The Conserved RNA Exonuclease Rexo5 Is Required for 3′ End Maturation of 28S rRNA, 5S rRNA, and snoRNAs

open access: yesCell Reports, 2017
Non-coding RNA biogenesis in higher eukaryotes has not been fully characterized. Here, we studied the Drosophila melanogaster Rexo5 (CG8368) protein, a metazoan-specific member of the DEDDh 3′-5′ single-stranded RNA exonucleases, by genetic, biochemical,
Stefanie Gerstberger   +8 more
doaj   +1 more source

LncRNA SNHG15 contributes to doxorubicin resistance of osteosarcoma cells through targeting the miR-381-3p/GFRA1 axis

open access: yesOpen Life Sciences, 2020
Osteosarcoma is a common primary malignant bone cancer. Long noncoding RNA small nucleolar RNA host gene 15 (SNHG15) has been reported to play an oncogenic role in many cancers.
Zhang Jinshan   +5 more
doaj   +1 more source

Non-Coding RNA Sequencing of Equine Endometrium During Maternal Recognition of Pregnancy. [PDF]

open access: yes, 2019
Maternal recognition of pregnancy (MRP) in the mare is not well defined. In a non-pregnant mare, prostaglandin F2α (PGF) is released on day 14 post-ovulation (PO) to cause luteal regression, resulting in loss of progesterone production. Equine MRP occurs
Bouma, Gerrit J   +10 more
core   +1 more source

Interaction and cross-talk between non-coding RNAs. [PDF]

open access: yes, 2017
Non-coding RNA (ncRNA) has been shown to regulate diverse cellular processes and functions through controlling gene expression. Long non-coding RNAs (lncRNAs) act as a competing endogenous RNAs (ceRNAs) where microRNAs (miRNAs) and lncRNAs regulate each ...
Dahiya, Rajvir   +3 more
core   +2 more sources

Identification of additional regulatory RNPs that impact rRNA and U6 snRNA methylation

open access: yesBiology Open, 2018
Ribosomes can be heterogeneous, and the major contributor to ribosome heterogeneity is variation in rRNA modification. There are two major types of rRNA modification, pseudouridylation and ribose methylation.
Marilyn F. Burke   +2 more
doaj   +1 more source

Loss of SNORA73 reprograms cellular metabolism and protects against steatohepatitis

open access: yesNature Communications, 2021
Lipid induced stress contributes to metabolic diseases. Here the authors identify small nucleolar RNA 73 (SNORA73) in a screen for genes that protect against lipotoxicity and show that deficiency of SNORA73 reprograms oxidative metabolism and protects ...
Arthur C. Sletten   +13 more
doaj   +1 more source

Diverse human extracellular RNAs are widely detected in human plasma

open access: yesNature Communications, 2016
Extracellular miRNAs are present in a variety of bodily fluids. Here, Freedman et al. analysed plasma-derived RNA by RNA-seq from 40 people followed by targeted RT-qPCR in an additional 2,763 people, and report over 1,000 extracellular RNAs including ...
Jane E. Freedman   +19 more
doaj   +1 more source

Molecular determinants that govern scaRNA processing by Drosha/DGCR8

open access: yesBiology Open, 2020
The Cajal body (CB) is a subnuclear domain that participates in the biogenesis of many different types of ribonucleoproteins (RNPs), including small nuclear RNPs (snRNPs), small Cajal body-specific RNPs (scaRNPs) and telomerase.
Douglas M. McLaurin   +3 more
doaj   +1 more source

LncRNA SNHG1: role in tumorigenesis of multiple human cancers

open access: yesCancer Cell International, 2023
Small nucleolar RNA host gene 1 (SNHG1) is an important member of the SNHG family. This family is composed of a group of host genes that can be processed into small nucleolar RNAs and play important biological functions.
Huang Zeng   +4 more
doaj   +1 more source

Unusual features of pomoviral RNA movement [PDF]

open access: yes, 2013
This work is partially supported by the Scottish Government’s Rural and Environment Science and Analytical Services (RESAS) DivisionPotato mop-top pomovirus (PMTV) is one of a few viruses that can move systemically in plants in the absence of the capsid ...
Bragard, Claude   +6 more
core   +1 more source

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