Results 21 to 30 of about 34,836 (187)

Commuting to Work: Nucleolar Long Non-Coding RNA Control Ribosome Biogenesis from Near and Far

open access: yesNon-Coding RNA, 2021
Gene expression is an essential process for cellular growth, proliferation, and differentiation. The transcription of protein-coding genes and non-coding loci depends on RNA polymerases.
Victoria Mamontova   +3 more
doaj   +1 more source

Small Nucleolar Derived RNAs as Regulators of Human Cancer

open access: yesBiomedicines, 2022
In the past decade, RNA fragments derived from full-length small nucleolar RNAs (snoRNAs) have been shown to be specifically excised and functional.
Alexander Bishop Coley   +3 more
doaj   +1 more source

Small Nucleolar RNAs in Pseudoexfoliation Glaucoma

open access: yesCells, 2022
Small nucleolar RNAs (snoRNAs) are small non-coding regulatory RNAs that have been investigated extensively in recent years. However, the relationship between snoRNA and glaucoma is still unknown. This study aims to analyze the levels of snoRNA expression in the aqueous humor (AH) of patients with pseudoexfoliation glaucoma (PEXG) compared to a control
Karolina Gasińska   +5 more
openaire   +4 more sources

The epitranscriptome of small non-coding RNAs

open access: yesNon-coding RNA Research, 2021
Small non-coding RNAs are short RNA molecules and involved in many biological processes, including cell proliferation and differentiation, immune response, cell death, epigenetic regulation, metabolic control.
Xiaoyu Li, Jinying Peng, Chengqi Yi
doaj   +1 more source

BMAL1 Associates with NOP58 in the Nucleolus and Contributes to Pre-rRNA Processing

open access: yesiScience, 2020
Summary: The transcription factor BMAL1 is a core element of the circadian clock that contributes to cyclic control of genes transcribed by RNA polymerase II.
Marlene Cervantes   +5 more
doaj   +1 more source

Small nucleolar RNAs in cancer [PDF]

open access: yesBiochimica et Biophysica Acta (BBA) - Reviews on Cancer, 2012
Non-coding RNAs (ncRNAs) are important regulatory molecules involved in various physiological and cellular processes. Alterations of ncRNAs, particularly microRNAs, play crucial roles in tumorigenesis. Accumulating evidence indicates that small nucleolar RNAs (snoRNAs), another large class of small ncRNAs, are gaining prominence and more actively ...
Kaiissar, Mannoor   +2 more
openaire   +2 more sources

Integrated analysis reveals a potential cuproptosis-related ceRNA axis SNHG17/miR-29a-3p/GCSH in prostate adenocarcinoma

open access: yesHeliyon, 2023
Cuproptosis is a novel form of programmed cell death. The role and mechanism of cuproptosis-related genes in prostate adenocarcinoma have not been fully understood. In this study, a series of bioinformatic analyses were performed.
Shuyuan Xiao, Weiyang Lou
doaj   +1 more source

Bidirectional nucleolar dysfunction in C9orf72 frontotemporal lobar degeneration

open access: yesActa Neuropathologica Communications, 2017
An intronic GGGGCC expansion in C9orf72 is the most common known cause of both frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS). The repeat expansion leads to the generation of sense and antisense repeat RNA aggregates and
Sarah Mizielinska   +9 more
doaj   +1 more source

Small RNA signatures of the anterior cruciate ligament from patients with knee joint osteoarthritis

open access: yesFrontiers in Molecular Biosciences, 2023
Introduction: The anterior cruciate ligament (ACL) is susceptible to degeneration, resulting in joint pain, reduced mobility, and osteoarthritis development.
Yalda A. Kharaz   +6 more
doaj   +1 more source

Small RNA expression and deep sequencing analyses of the nucleolus reveal the presence of nucleolus-associated microRNAs

open access: yesFEBS Open Bio, 2014
Micro RNAs (miRNA) are non-coding RNAs expressed in the cytoplasm as their mature, 21–22-nucleotide short forms. More recently, mature miRNAs have also been detected in the nucleus, raising the possibility that their spatial distribution may be more ...
Baoyan Bai, Hester Liu, Marikki Laiho
doaj   +1 more source

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