Results 21 to 30 of about 442,180 (329)

Small nucleolar RNAs in cancer [PDF]

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 2012
Non-coding RNAs (ncRNAs) are important regulatory molecules involved in various physiological and cellular processes. Alterations of ncRNAs, particularly microRNAs, play crucial roles in tumorigenesis. Accumulating evidence indicates that small nucleolar RNAs (snoRNAs), another large class of small ncRNAs, are gaining prominence and more actively ...
Feng Jiang, Kaiissar Mannoor, Jipei Liao
openaire   +3 more sources

Long noncoding RNA ZFAS1 promoting small nucleolar RNA-mediated 2′-O-methylation via NOP58 recruitment in colorectal cancer

Molecular Cancer, 2020
Background Increasing evidence supports the role of small nucleolar RNAs (snoRNAs) and long non-coding RNAs (lncRNAs) as master gene regulators at the epigenetic modification level.
Huizhe Wu, W. Qin, Senxu Lu, Xiufang Wang, Jing Zhang, T. Sun, Xiaoyun Hu, Yalun Li, Qiuchen Chen, Yuanhe Wang, Haishan Zhao, H. Piao, Rui Zhang, M. Wei   +13 more
semanticscholar   +1 more source

Evolution of small nucleolar RNAs in nematodes [PDF]

Nucleic Acids Research, 2006
In contrast to mRNAs, which are templates for translating proteins, non-protein coding (npc) RNAs (also known as 'non-coding' RNA, ncRNA), exhibit various functions in different compartments and developmental stages of the cell. Small nucleolar RNAs (snoRNAs), one of the largest classes of npcRNAs, guide post-transcriptional modifications of other RNAs
Jürgen Schmitz, Martin Kiefmann, Anja op de Bekke, Anja Zemann, Jürgen Brosius   +4 more
openaire   +3 more sources

Long Non-Coding Small Nucleolar RNA Host Genes (SNHGs) in Endocrine-Related Cancers

OncoTargets and Therapy, 2020
Long non-coding RNAs (lncRNAs) are emerging regulators of a diverse range of biological processes through various mechanisms. Genome-wide association studies of tumor samples have identified several lncRNAs, which act as either oncogenes or tumor ...
Yuan Qin, Wei Sun, Zhihong Wang, W. Dong, Liang He, Ting Zhang, Hao Zhang   +6 more
semanticscholar   +1 more source

Nucleolar Localization Elements ofXenopus laevisU3 Small Nucleolar RNA [PDF]

Molecular Biology of the Cell, 1998
The Nucleolar Localization Elements (NoLEs) of Xenopus laevis U3 small nucleolar RNA (snoRNA) have been defined. Fluorescein-labeled wild-type U3 snoRNA injected intoXenopus oocyte nuclei localized specifically to nucleoli as shown by fluorescence microscopy. Injection of mutated U3 snoRNA revealed that the 5′ region containing Boxes A and A′, known to
Thilo S. Lange, Michael Ezrokhi, Anton V. Borovjagin, Rafael Rivera-León, Melanie T. North, Susan A. Gerbi   +5 more
openalex   +5 more sources

SNHG7 Facilitates Glioblastoma Progression by Functioning as a Molecular Sponge for MicroRNA-449b-5p and Thereby Increasing MYCN Expression

Technology in Cancer Research & Treatment, 2020
Background and Aims: Long noncoding RNA (small nucleolar RNA host gene 7) has been reported to be involved in multiple malignancies and acts as an oncogene.
Yaogang Chen BM, Shaoyong Yuan BM, Tieying Ning BM, Huiqing Xu BM, Bo Guan MM   +4 more
doaj   +1 more source

Functional diversity of small nucleolar RNAs

Nucleic Acids Research, 2019
AbstractSmall nucleolar RNAs (snoRNAs) are short non-protein-coding RNAs with a long-recognized role in tuning ribosomal and spliceosomal function by guiding ribose methylation and pseudouridylation at targeted nucleotide residues of ribosomal and small nuclear RNAs, respectively.
Tomaž Bratkovič, Janja Božič, Boris Rogelj   +2 more
openalex   +4 more sources

The C/D box small nucleolar RNA SNORD52 regulated by Upf1 facilitates Hepatocarcinogenesis by stabilizing CDK1

Theranostics, 2020
Rationale: Understanding the roles of small nucleolar RNAs (snoRNAs) in hepatocarcinogenesis will provide new avenues to identify diagnostic and therapeutic targets for hepatocellular carcinoma (HCC). Our previous research confirmed the tumor-suppressive
Cuicui Li, Long Wu, Pengpeng Liu, Kun Li, Zhongling Zhang, Yue-ming He, Quanyan Liu, Ping Jiang, Zhiyong Yang, Zhisu Liu, Yufeng Yuan, Lei Chang   +11 more
semanticscholar   +1 more source

LncRNA-LALR1 upregulates small nucleolar RNA SNORD72 to promote growth and invasion of hepatocellular carcinoma

Aging, 2020
Hepatocellular carcinoma (HCC) is one of the most prevalent cancers and currently the second leading cause of cancer-related mortality worldwide. One recent study reported that lncRNA-LALR1 promotes liver regeneration, the role and underlying mechanisms ...
Lin-hong Mao, Sisi Chen, Xiao-qin Li, Feng Xu, Jing Lei, Qing-liang Wang, Li Luo, Haiyan Cao, Xin Ge, T. Ran, Xue Li, M. Zou, Zhihang Zhou, Xiao-ling Wu, Song He   +14 more
semanticscholar   +1 more source

SSB-1 of the yeast Saccharomyces cerevisiae is a nucleolar-specific, silver-binding protein that is associated with the snR10 and snR11 small nuclear RNAs [PDF]

, 1990
SSB-1, the yeast single-strand RNA-binding protein, is demonstrated to be a yeast nucleolar-specific, silver-binding protein. In double-label immunofluorescence microscopy experiments antibodies to two other nucleolar proteins, RNA Pol I 190-kD and ...
Abelson, John, Campbell, Judith, Clark, Michael W., Yip, Man Lun R.   +3 more
core   +2 more sources