Results 11 to 20 of about 60,360 (226)

Small Nucleolar (Sno)RNA: Therapy Lays in Translation

Non-Coding RNA, 2023
The ribosome is one of the largest complexes in the cell. Adding to its complexity are more than 200 RNA modification sites present on ribosomal RNAs (rRNAs) in a single human ribosome.
Ofri Rabany, Daphna Nachmani
doaj   +3 more sources

Small Nucleolar RNAs Tell a Different Tale [PDF]

Trends in Genetics, 2019
Transcribing RNA Polymerase II interacts with multiple factors that orchestrate maturation and stabilisation of messenger RNA. For the majority of noncoding RNAs, the polymerase complex employs entirely different strategies, which usually direct the nascent transcript to ribonucleolytic degradation.
Joanna Kufel, Pawel Grzechnik
exaly   +4 more sources

Are Small Nucleolar RNAs “CRISPRable”? A Report on Box C/D Small Nucleolar RNA Editing in Human Cells [PDF]

Frontiers in Pharmacology, 2019
CRISPR technologies are nowadays widely used for targeted knockout of numerous protein-coding genes and for the study of various processes and metabolic pathways in human cells. Most attention in the genome editing field is now focused on the cleavage of
Julia A. Filippova, Anastasiya M. Matveeva, Anastasiya M. Matveeva, Evgenii S. Zhuravlev, Evgenia A. Balakhonova, Daria V. Prokhorova, Daria V. Prokhorova, Sergey J. Malanin, Raihan Shah Mahmud, Tatiana V. Grigoryeva, Ksenia S. Anufrieva, Ksenia S. Anufrieva, Dmitry V. Semenov, Valentin V. Vlassov, Grigory A. Stepanov, Grigory A. Stepanov   +15 more
doaj   +4 more sources

SnoRNA and lncSNHG: Advances of nucleolar small RNA host gene transcripts in anti-tumor immunity

Frontiers in Immunology, 2023
The small nucleolar RNA host genes (SNHGs) are a group of genes that can be transcript into long non-coding RNA SNHG (lncSNHG) and further processed into small nucleolar RNAs (snoRNAs).
Hao Xiao, Hao Xiao, Xin Feng, Xin Feng, Mengjun Liu, Mengjun Liu, Hanwen Gong, Hanwen Gong, Xiao Zhou, Xiao Zhou   +9 more
doaj   +3 more sources

A non-canonical role for a small nucleolar RNA in ribosome biogenesis and senescence. [PDF]

Cell
Cheng Y, Wang S, Zhang H, Lee JS, Ni C, Guo J, Chen E, Wang S, Acharya A, Chang TC, Buszczak M, Zhu H, Mendell JT.   +12 more
europepmc   +2 more sources

Small Nucleolar RNAs in Pseudoexfoliation Glaucoma

Cells, 2022
Small nucleolar RNAs (snoRNAs) are small non-coding regulatory RNAs that have been investigated extensively in recent years. However, the relationship between snoRNA and glaucoma is still unknown. This study aims to analyze the levels of snoRNA expression in the aqueous humor (AH) of patients with pseudoexfoliation glaucoma (PEXG) compared to a control
Karolina Gasińska, Marcin Czop, Ewa Kosior-Jarecka, Dominika Wróbel-Dudzińska, Janusz Kocki, Tomasz Żarnowski   +5 more
openaire   +4 more sources

The epitranscriptome of small non-coding RNAs

Non-coding RNA Research, 2021
Small non-coding RNAs are short RNA molecules and involved in many biological processes, including cell proliferation and differentiation, immune response, cell death, epigenetic regulation, metabolic control.
Xiaoyu Li, Jinying Peng, Chengqi Yi
doaj   +1 more source

BMAL1 Associates with NOP58 in the Nucleolus and Contributes to Pre-rRNA Processing

iScience, 2020
Summary: The transcription factor BMAL1 is a core element of the circadian clock that contributes to cyclic control of genes transcribed by RNA polymerase II.
Marlene Cervantes, Ignasi Forné, Suman Ranjit, Enrico Gratton, Axel Imhof, Paolo Sassone-Corsi   +5 more
doaj   +1 more source

Small nucleolar RNAs in cancer [PDF]

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 2012
Non-coding RNAs (ncRNAs) are important regulatory molecules involved in various physiological and cellular processes. Alterations of ncRNAs, particularly microRNAs, play crucial roles in tumorigenesis. Accumulating evidence indicates that small nucleolar RNAs (snoRNAs), another large class of small ncRNAs, are gaining prominence and more actively ...
Kaiissar, Mannoor, Jipei, Liao, Feng, Jiang   +2 more
openaire   +2 more sources

SSB-1 of the yeast Saccharomyces cerevisiae is a nucleolar-specific, silver-binding protein that is associated with the snR10 and snR11 small nuclear RNAs [PDF]

, 1990
SSB-1, the yeast single-strand RNA-binding protein, is demonstrated to be a yeast nucleolar-specific, silver-binding protein. In double-label immunofluorescence microscopy experiments antibodies to two other nucleolar proteins, RNA Pol I 190-kD and ...
Abelson, John, Campbell, Judith, Clark, Michael W., Yip, Man Lun R.   +3 more
core   +2 more sources