Results 61 to 70 of about 442,180 (329)
SnoRNA and lncSNHG: Advances of nucleolar small RNA host gene transcripts in anti-tumor immunity
Frontiers in Immunology, 2023 The small nucleolar RNA host genes (SNHGs) are a group of genes that can be transcript into long non-coding RNA SNHG (lncSNHG) and further processed into small nucleolar RNAs (snoRNAs).
Hao Xiao +9 more
doaj +1 more source
Cancer Medicine, 2020 The main purpose of the present study is to screen prognostic small nucleolar RNA (snoRNA) markers using the RNA‐sequencing (RNA‐seq) dataset of The Cancer Genome Atlas (TCGA) sarcoma cohort.
Jianwei Liu +4 more
semanticscholar +1 more source
, 2016 The nucleus is arguably the defining characteristic of eukaryotes, distinguishing their cell organisation from both bacteria and archaea. Though the evolutionary history of the nucleus remains the subject of debate, its emergence differs from several ...
McCulloch, Richard, Navarro, Miguel
core +1 more source
Human snoRNA-93 is processed into a microRNA-like RNA that promotes breast cancer cell invasion
npj Breast Cancer, 2017 RNA: Small nucleolar-derived RNA contributes to tumor invasiveness A short microRNA-like fragment excised from a small nucleolar RNA (called a snoRNA-derived RNA or sdRNA) contributes to the invasiveness of breast cancer cells.
Dillon G. Patterson +23 more
doaj +1 more source
Molecular determinants that govern scaRNA processing by Drosha/DGCR8
Biology Open, 2020 The Cajal body (CB) is a subnuclear domain that participates in the biogenesis of many different types of ribonucleoproteins (RNPs), including small nuclear RNPs (snRNPs), small Cajal body-specific RNPs (scaRNPs) and telomerase.
Douglas M. McLaurin +3 more
doaj +1 more source
LncRNA SNHG1: role in tumorigenesis of multiple human cancers
Cancer Cell International, 2023 Small nucleolar RNA host gene 1 (SNHG1) is an important member of the SNHG family. This family is composed of a group of host genes that can be processed into small nucleolar RNAs and play important biological functions.
Huang Zeng +4 more
doaj +1 more source
Predicting RNA-small molecule binding sites by 3D structure [PDF]
arXiv, 2023 The prediction of RNA-small molecule binding sites is crucial for the discovery of effective drugs. Various computational methods have been developed to address this challenge, using information about the structure and sequence of RNA. In this study, we introduce CplxCavity, a combination of a new algorithm and a machine learning model specifically ...
arxiv
Nucleolar dominance and DNA methylation directed by small interfering RNA [PDF]
, 2008 In the December 5th issue of Molecular Cell, Preuss et al. (2008) demonstrated a link between small interfering RNA (siRNA)-directed de novo DNA methylation and rDNA silencing in nucleolar ...
Finigan, P., Martienssen, R. A.
core +1 more source
Identification of additional regulatory RNPs that impact rRNA and U6 snRNA methylation
Biology Open, 2018 Ribosomes can be heterogeneous, and the major contributor to ribosome heterogeneity is variation in rRNA modification. There are two major types of rRNA modification, pseudouridylation and ribose methylation.
Marilyn F. Burke +2 more
doaj +1 more source
RNA-Seq of the nucleolus reveals abundant SNORD44-derived small RNAs. [PDF]
PLoS ONE, 2014 Small non-coding RNAs represent RNA species that are not translated to proteins, but which have diverse and broad functional activities in physiological and pathophysiological states. The knowledge of these small RNAs is rapidly expanding in part through
Baoyan Bai +3 more
doaj +1 more source