Results 41 to 50 of about 1,233,249 (248)

A modified perturbation method in which the applicable range of a small parameter for the solution is extended much larger than that by the conventional perturbation method

Mechanical Engineering Journal, 2021
A modified perturbation method, in which the applicable range of a small parameter ε for the solution is extended larger than that by the conventional perturbation method, is applied to two simple heat transfer problems with temperature-dependent thermal
Sumio KATO, Shoichi MATSUDA
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Solution of the problem with a small parameter in suspension filtration in a porous medium

Известия Томского политехнического университета: Инжиниринг георесурсов
Relevance. The necessity to calculate the changes in filtration properties during injection of suspensions for subsequent forecasting of technological parameters of wells. This calculation is complicated by the presence of different-scale effects, since
Ekaterina N. Arkhipova, Alexander Y. Gilmanov, Alexander P. Shevelev   +2 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

A Note on the Domain of Attraction for the Stationary Solution to a Singularly Perturbed Parabolic Equation

Моделирование и анализ информационных систем, 2017
We consider  a boundary-value problem  for a singularly  perturbed parabolic  equation with an initial function  independent of a perturbation parameter in the case where a degenerate stationary equation  has smooth possibly intersecting roots.
Mikhail A. Terentyev
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Moving Front Solution of the Reaction-Diffusion Problem

Моделирование и анализ информационных систем, 2017
In  this  paper,  we study  the  moving  front solution  of the  reaction-diffusion  initialboundary value problem  with a small diffusion coefficient. Problems  in such statements can be used to model physical processes associated  with the propagation ...
Evgeny A. Antipov, Vladimir T. Volkov, Natalia T. Levashova, Nikolay N. Nefedov   +3 more
doaj   +1 more source

GLOBAL ASYMPTOTIC STEP LIKE SOLUTIONS TO THE SINGULARLY PERTURBED KORTEWEG-DE VRIES EQUATION WITH VARIABLE COEFFICIENTS

Міжнародний науково-технічний журнал "Проблеми керування та інформатики", 2020
The paper deals with the Korteweg-de Vries equation with variable coefficients and a small parameter at the highest derivative. Similar equations arise while mathematical simulation of wave processes in inhomogeneous media with variable characteristics ...
С.І. Ляшко, В.Г. Самойленко, Юл.І. Самойленко, І.В. Гап’як, Н.І. Ляшко, М.С. Орлова   +5 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source