Results 61 to 70 of about 1,176,120 (248)
Reducing Friction with a Liquid Film on the Body Surface
A flow of a thin layer of liquid is simulated on a flat surface of a body located in a stream of air. Liquid film on the surface of the body reduces frictional resistance and can be used as a boundary layer control element.
Nikolay Klyuev +2 more
doaj +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Random Homogenization in a Domain with Light Concentrated Masses
In the paper, we consider an elliptic problem in a domain with singular stochastic perturbation of the density located near the boundary, depending on a small parameter.
Gregory A. Chechkin +1 more
doaj +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
In this paper it is shown that the problem of quasistatic three-dimensional stress-strain state of elastic pipes of a variable cross-section under the influence of internal pressure can be solved economically and quickly by a numerical-analytical rapid ...
Nikolay G. Burago, Ilya S. Nikitin
doaj
Some scenarios for delaying the loss of stability in differential systems with multiscale variables
The paper is devoted to a detailed study of the mechanism of stability loss in dynamical systems with fast and slow variables. The need for such research arises in various applied problems, in particular, in connection with the study of combustion, and ...
O. S. Kipkaeva, E. A. Shchepakina
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
An approximate group classification of a perturbed subdiffusion equation
A problem of the Lie point approximate symmetry group classification of a perturbed subdiffusion equation with a small parameter is solved. The classification is performed with respect to anomalous diffusion coefficient which is considered as a function ...
Stanislav Yu Lukashchuk
doaj +1 more source

