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Exploration of small RNAs. [PDF]

open access: yesPLoS Genetics, 2008
For several decades, only a limited number of noncoding RNAs, such as ribosomal and transfer RNA, have been studied in any depth. In recent years, additional species of noncoding RNAs have increasingly been discovered. Of these, small RNA species attract
Hideya Kawaji, Yoshihide Hayashizaki
doaj   +4 more sources

Navigating dietary small RNAs [PDF]

open access: yesGenes & Nutrition, 2017
When a novel nutritional concept comes along, scientists become enthusiastic and start new explorations. In 2012, the field was enthralled with a study suggesting plant-based nucleic acid “information” acts as a bioactive to regulate animal metabolism.
Kendal D. Hirschi
doaj   +3 more sources

Hidden layers of human small RNAs [PDF]

open access: yesBMC Genomics, 2008
Background Small RNA attracts increasing interest based on the discovery of RNA silencing and the rapid progress of our understanding of these phenomena.
Daub Carsten O   +11 more
doaj   +3 more sources

Identification of wounding and topping responsive small RNAs in tobacco (Nicotiana tabacum) [PDF]

open access: yesBMC Plant Biology, 2012
Background MicroRNAs (miRNAs) and short interfering RNAs (siRNAs) are two major classes of small RNAs. They play important regulatory roles in plants and animals by regulating transcription, stability and/or translation of target genes in a sequence ...
Tang She   +7 more
doaj   +4 more sources

Comprehensive Small RNA-Seq of Adeno-Associated Virus (AAV)-Infected Human Cells Detects Patterns of Novel, Non-Coding AAV RNAs in the Absence of Cellular miRNA Regulation. [PDF]

open access: yesPLoS ONE, 2016
Most DNA viruses express small regulatory RNAs, which interfere with viral or cellular gene expression. For adeno-associated virus (AAV), a small ssDNA virus with a complex biphasic life cycle miRNAs or other small regulatory RNAs have not yet been ...
Catrin Stutika   +6 more
doaj   +7 more sources

Diversity and Versatility in Small RNA-Mediated Regulation in Bacterial Pathogens

open access: yesFrontiers in Microbiology, 2021
Bacterial gene expression is under the control of a large set of molecules acting at multiple levels. In addition to the transcription factors (TFs) already known to be involved in global regulation of gene expression, small regulatory RNAs (sRNAs) are ...
Brice Felden, Yoann Augagneur
doaj   +1 more source

Vloga malih RNK pri odzivu rastlin na okužbo s patogenimi organizmi

open access: yesActa Agriculturae Slovenica, 2022
Rastline imajo razvite raznolike in kompleksne mehanizme za regulacijo izražanja genov. Nedavno je bil odkrit nov mehanizem, imenovan RNK interferenca (RNKi).
Urban KUNEJ, Ester STAJIČ
doaj   +1 more source

Small silencing RNAs [PDF]

open access: yesCurrent Biology, 2007
PIWI-interacting RNAs (piRNAs), 24–30 nucleotide long RNAs found in the germ cells of animals, are unique among small silencing RNAs in that they require neither an RdRP nor Dicer for their production (Figure 1Figure 1C). Instead, they are thought to derive from single-stranded precursor RNAs tens or hundreds of thousands of nucleotides long.
Matranga, Christian, Zamore, Phillip D.
openaire   +2 more sources

Small RNA database [PDF]

open access: yesNucleic Acids Research, 1996
The small RNA database is a compilation of all the small size RNA sequences available to date, including nuclear, nucleolar, cytoplasmic and mitochondrial small RNAs from eukaryotic organisms and small RNAs from prokaryotic cells as well as viruses. Currently, about 600 small RNA sequences are in our database.
J, Gu, Y, Chen, R, Reddy
openaire   +6 more sources

Circulating small RNA signatures differentiate accurately the subtypes of muscular dystrophies: small-RNA next-generation sequencing analytics and functional insights

open access: yesRNA Biology, 2022
Muscular dystrophies are a group of rare and severe inherited disorders mainly affecting the muscle tissue. Duchene Muscular Dystrophy, Myotonic Dystrophy types 1 and 2, Limb Girdle Muscular Dystrophy and Facioscapulohumeral Muscular Dystrophy are some ...
Andrea C. Kakouri   +17 more
doaj   +1 more source

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