Results 21 to 30 of about 536,647 (305)
Profiling of RNAs from Human Islet-Derived Exosomes in a Model of Type 1 Diabetes [PDF]
, 2019 Type 1 diabetes (T1D) is characterized by the immune-mediated destruction of insulin-producing islet β cells. Biomarkers capable of identifying T1D risk and dissecting disease-related heterogeneity represent an unmet clinical need.
Evans-Molina, Carmella +4 more
core +2 more sources
Biologia Plantarum, 2020 Small RNAs (sRNAs) are essential components of gene-regulatory networks, which guide plant development and tune it to environmental challenges. Though the past years have witnessed evidences on sRNA importance for stress response, there is scarce data on
E. APOSTOLOVA +7 more
doaj +1 more source
RNA Interference and Small RNA Analysis [PDF]
Cold Spring Harbor Protocols, 2019 Small silencing RNAs have provided powerful reverse genetics tools and have opened new areas of research. This introduction describes the use of RNAi to suppress expression of individual genes for loss-of-function analysis. It also summarizes methods for measuring specific and global changes in small RNA expression, as well as methods to inhibit the ...
Chengjian, Li, Phillip D, Zamore
openaire +2 more sources
Interaction and cross-talk between non-coding RNAs. [PDF]
, 2017 Non-coding RNA (ncRNA) has been shown to regulate diverse cellular processes and functions through controlling gene expression. Long non-coding RNAs (lncRNAs) act as a competing endogenous RNAs (ceRNAs) where microRNAs (miRNAs) and lncRNAs regulate each ...
Dahiya, Rajvir +3 more
core +2 more sources
Role of RNA Interference (RNAi) in the Moss Physcomitrella patens [PDF]
, 2013 RNA interference (RNAi) is a mechanism that regulates genes by either transcriptional (TGS) or posttranscriptional gene silencing (PTGS), required for genome maintenance and proper development of an organism.
Arif, Muhammad Asif +2 more
core +3 more sources
Small RNAs making a small protein [PDF]
Proceedings of the National Academy of Sciences, 2007 Small RNAs (sRNAs), often called noncoding RNAs, are widespread in all organisms and are used to control diverse cellular processes. A large class of sRNAs is involved in the regulation of gene expression primarily at posttranscriptional levels through base-pairing.
Teppei, Morita, Hiroji, Aiba
openaire +2 more sources
Проблемы особо опасных инфекций, 2017 Currently, bacterial small RNAs with regulatory functions are characterized as a heterogeneous claster of highly structured single-stranded RNAs which usually would not be translated into proteins. A large group of small RNAs consists of small regulatory
R. V. Pisanov +2 more
doaj +1 more source
Dicer-dependent biogenesis of small RNAs derived from 7SL RNA. [PDF]
PLoS ONE, 2012 It has been reported that decreased Dicer expression leads to Alu RNAs accumulation in human retinal pigmented epithelium cells, and Dicer may process the endogenous SINE/B1 RNAs (the rodent equivalent of the primate Alu RNAs) into small interfering RNAs
Yong-Feng Ren +7 more
doaj +1 more source
Viruses, 2021 Cleavage of double-stranded RNA is described as an evolutionary conserved host defense mechanism against viral infection. Small RNAs are the product and triggers of post transcriptional gene silencing events. Up until now, the relevance of this mechanism
Claudius Grehl +6 more
doaj +1 more source
MicroRNA-like RNAs from the same miRNA precursors play a role in cassava chilling responses [PDF]
, 2017 MicroRNAs (miRNAs) are known to play important roles in various cellular processes and stress responses. MiRNAs can be identified by analyzing reads from high-throughput deep sequencing.
Chen, Xin +5 more
core +3 more sources