Results 71 to 80 of about 598,726 (234)

Safety and Immunogenicity of Modified Vaccinia Ankara-Bavarian Nordic Smallpox Vaccine in Vaccinia-Naive and Experienced Human Immunodeficiency Virus-Infected Individuals: An Open-Label, Controlled Clinical Phase II Trial

Open Forum Infectious Diseases, 2015
Background First- and second-generation smallpox vaccines are contraindicated in individuals infected with human immunodeficiency virus (HIV). A new smallpox vaccine is needed to protect this population in the context of biodefense preparedness.
E. Overton, J. Stapleton, I. Frank, Shawn Hassler, P. Goepfert, David E. Barker, E. Wagner, A. von Krempelhuber, G. Virgin, J. Weigl, T. Meyer, Jutta Müller, Nicole Bädeker, Robert Gruenert, P. Young, Siegfried Rösch, J. Maclennan, Nathaly Arndtz-Wiedemann, P. Chaplin   +18 more
semanticscholar   +1 more source

Interdisciplinary Approach to Monkeypox Prevention: Integrating Nanobiosensors, Nanovaccines, Artificial Intelligence, Visual Arts, and Social Sciences

Small Structures, Volume 6, Issue 7, July 2025.
This illustration depicts a comprehensive strategy against monkeypox, showcasing its transmission, symptoms, and prevention. Centralized around nanomaterials and biosensors, it integrates early screening, Internet of Things, vaccination, and community involvement through collaboration among healthcare workers, scientists, researchers, social groups ...
Vishal Chaudhary, Lucky Lucky, Harsh Sable, Nikhil Bhalla   +3 more
wiley   +1 more source

A Multicenter, Open-Label, Controlled Phase II Study to Evaluate Safety and Immunogenicity of MVA Smallpox Vaccine (IMVAMUNE) in 18–40 Year Old Subjects with Diagnosed Atopic Dermatitis

PLoS ONE, 2015
Background Replicating smallpox vaccines can cause severe complications in individuals with atopic dermatitis (AD). Prior studies evaluating Modified Vaccinia Ankara virus (MVA), a non-replicating vaccine in humans, showed a favorable safety and ...
R. Greenberg, Y. Hurley, D. Dinh, S. Mraz, J. G. Vera, D. von Bredow, A. von Krempelhuber, Siegfried Roesch, G. Virgin, Nathaly Arndtz-Wiedemann, T. Meyer, D. Schmidt, R. Nichols, P. Young, P. Chaplin   +14 more
semanticscholar   +1 more source

The Essentials of Smallpox Vaccination [PDF]

The American Journal of the Medical Sciences, 1922
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Rosenau, Milton J., McCOY, George W.
openaire   +3 more sources

Clinical Manifestations in 32 Cases of Mpox Infection: A Retrospective Study in a Single Dermatology Clinic in Japan

The Journal of Dermatology, Volume 52, Issue 7, Page 1192-1196, July 2025.
ABSTRACT Mpox, a zoonotic orthopox virus, has re‐emerged globally since May 2022. In Tokyo, 168 cases were reported in 2023. About 20% were diagnosed in our department. In this study, we analyzed the clinical and epidemiological characteristics of 32 mpox patients diagnosed in our department in 2023.
Amika Nakazawa, Tomonobu Ito, Takafumi Numata, Noriyasu Sakai, Yukari Okubo, Kazutoshi Harada   +5 more
wiley   +1 more source

Dangerous Liaisons: Unveiling the Co‐Constitution of Emerging Infectious Diseases and Industrial Meat Production

Antipode, Volume 57, Issue 4, Page 1320-1341, July 2025.
Abstract Outbreaks of highly pathogenic avian influenza (HPAI) have intensified over the last decade, spotlighting the concept of “epicentre” as a means of locating disease origins. Although epicentre thinking can facilitate rapid interventions, it often overlooks the political‐economic and ecological forces driving outbreaks.
Mariel Aguilar‐Støen, Jostein Jakobsen, Mads Barbesgaard, Rebecca Leigh Rutt, Ada Eldevik‐Stjernqvist   +4 more
wiley   +1 more source

TLR3 and TLR9 agonists improve postexposure vaccination efficacy of live smallpox vaccines. [PDF]

PLoS ONE, 2014
Eradication of smallpox and discontinuation of the vaccination campaign resulted in an increase in the percentage of unvaccinated individuals, highlighting the need for postexposure efficient countermeasures in case of accidental or deliberate viral ...
Tomer Israely, Sharon Melamed, Hagit Achdout, Noam Erez, Boaz Politi, Trevor Waner, Shlomo Lustig, Nir Paran   +7 more
doaj   +1 more source

Revolution of AAV in Drug Discovery: From Delivery System to Clinical Application

Journal of Medical Virology, Volume 97, Issue 6, June 2025.
ABSTRACT Adeno‐associated virus (AAV) is a non‐enveloped DNA virus infecting a wide variety of species, tissues, and cell types, which is recognized as a safe and effective method for delivering therapeutic transgenes. AAV vector is the most popular viral gene delivery system in clinical delivery systems with unique and multiple advantages, such as ...
Ling Yin, Hongliang He, Hongliang Zhang, Yuhua Shang, Chengbo Fu, Songquan Wu, Tengchuan Jin   +6 more
wiley   +1 more source

Strategies for the Modification of Vaccinia Virus towards a Better Vaccine Vector

Zoonoses
Vaccinia virus (VACV) confers cross-protective immunity against variola virus, the causative agent of smallpox, and has therefore been extensively exploited as a preventive vaccine.
Hao Sun, Xinwen Chen, Yun Wang
doaj   +1 more source

A Fix‐And‐Optimize Matheuristic to Solve the Location‐Allocation of Vaccination Facilities: Case of Jalisco, Mexico

Networks, Volume 85, Issue 4, Page 382-395, June 2025.
ABSTRACT Approximately 755 million cases and 7 million deaths have been reported since the COVID‐19 pandemic. Based on the availability of vaccines to contain the spread of COVID‐19, various vaccination plans have been implemented globally, some more effective than others, depending on each country's social, territorial, economic, and political ...
Marisol S. Romero‐Mancilla, Jaime Mora‐Vargas, Angel Ruiz   +2 more
wiley   +1 more source