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Epidemic size, duration and vaccine stockpiling following a large-scale attack with smallpox
On August 16th, 2018, we held Exercise Mataika to test preparedness for a worst-case scenario of a smallpox attack which begins in the Pacific and is followed by a larger scale attack in a highly populous Asian country.
C. R. MacIntyre+5 more
semanticscholar +1 more source
Le vaccin et ses simulacres : instaurer un être pour gérer une population, 1800-1865
The story of the smallpox vaccine is of particular interest for analysing the role of knowledge in the exercise of power after the Revolution. Rather than establishing compulsory vaccination, the French Government decided to intervene in the medical ...
Jean-Baptiste Fressoz
doaj +1 more source
Pandemic Prevention Paradigms: Understanding Global Health Governance
One Health is an emerging area of integrative studies and interventions aimed at preventing zoonotic diseases by addressing human, animal, and environmental interactions. A fundamental aspect of the concept is understanding how these interactions influence health outcomes among humans, animals, and ecosystems. Developed initially to respond to the need
Soheil Sadr+10 more
wiley +1 more source
Land Use Change and Infectious Disease Emergence
Abstract Major infectious diseases threatening human health are transmitted to people from animals or by arthropod vectors such as insects. In recent decades, disease outbreaks have become more common, especially in tropical regions, including new and emerging infections that were previously undetected or unknown. Even though there is growing awareness
M. Cristina Rulli+6 more
wiley +1 more source
Use of the LC16m8 Smallpox Vaccine in Immunocompromised Individuals Is Still Too Risky
We read with some concern the report by Yokote et al. ([1][1]), in which the authors recommend that LC16m8, a replicating smallpox vaccine licensed in Japan, be considered for use in persons who are immunocompromised.
Y. Danon, G. Sutter
semanticscholar +1 more source
Safety of Attenuated Smallpox Vaccine LC16m8 in Immunodeficient Mice
Freeze-dried live attenuated smallpox vaccine LC16m8 prepared in cell culture has been the sole smallpox vaccine licensed in Japan since 1975 and was recently recommended as a WHO stockpile vaccine. We evaluated the safety of recently remanufactured lots
H. Yokote+6 more
semanticscholar +1 more source
Due to the discontinuation of routine smallpox vaccination after its eradication in 1980, a large part of the human population remains naïve against smallpox and other members of the orthopoxvirus genus.
Damian Jandrasits+6 more
doaj
Men who have sex with men and people living with HIV are disproportionately affected in the 2022 multi-country monkeypox epidemic. The smallpox vaccine can induce cross-reactive antibodies against the monkeypox virus (MPXV) and reduce the risk of ...
Dapeng Li+14 more
doaj +1 more source
Smallpox vaccination carries a high risk of adverse events in recipients with a variety of contra-indications for live vaccines. Although alternative non-replicating vaccines have been described in the form of replication-deficient vaccine viruses, DNA ...
Sarah Reeman+4 more
doaj +1 more source