Results 141 to 150 of about 16,909 (206)

A Personalised Vaccination Program Based on Immune Reconstitution in Paediatric Cancer Survivors

Acta Paediatrica, EarlyView.
ABSTRACT Aims Paediatric cancer survivors often experience treatment‐induced immunosuppression, requiring post‐treatment revaccination. However, immune recovery timelines vary, and current revaccination guidelines, largely based on data of varied quality derived from studies on acute‐lymphoblastic‐leukaemia (ALL), may not be applicable across all ...
Menucha Jurkowicz, Raz Somech, Dan Dominissini, Nathan Keller, Efrat Dresner, Michal Paret, Gilad Sherman, Guy Katzenellenbogen, Elina Gelman, Keren Asraf, Ram Doolman, Atar Lev, Amos J. Simon, Helly Vernitsky, Assaf Barg, Hana Golan, Amos Toren, Michal Stein   +17 more
wiley   +1 more source

Meta‐Analysis: The Placebo Response in Modern Treatments for Cholestatic Pruritus: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

Alimentary Pharmacology &Therapeutics, EarlyView.
Placebo arms show substantial improvement in cholestatic pruritus, with up to 30% response rate. Estimates differed across outcome instruments, highlighting the importance of endpoint selection and realistic placebo assumptions in future trial design.
Igor Boechat Silveira, Leonardo Corrêa Süffert, Gustavo André Pedral Diniz Leite, Milena Ramos Tomé, Sarah Quick Lourenço de Lima, Gabriel André Pedral Diniz Leite, Bernardo de Faria Moraes, Pedro Robson Costa Passos, Guilherme Grossi Lopes Cançado   +8 more
wiley   +1 more source

Human iPSC‐Derived Vascularised Lung Organoids for Modelling COPD and Pulmonary Hypertension

Cell Proliferation, EarlyView.
Vascularised lung organoids (vLOs) that faithfully mimic human lung tissue architecture and disease pathology are critical for advancing pulmonary research but remain challenging to generate. Here, we developed a robust self‐organisation protocol to produce vLOs with cellular heterogeneity and functional vasculature. The engineered blood vessels within
Simin Jiang, Liangliang Tian, Jingge Qu, Yi Hong, Dian Chen, Zihang Pan, Huanyu Long, Lanhe Chu, Weijing Kong, Qiyang Yao, Xiaojing Ma, Yun Zhao, Baihui Ma, Kai Wang, Yahong Chen   +14 more
wiley   +1 more source

Phosphomimetic statherin‐derived peptide protects against intrinsic enamel erosion independently of sodium trimetaphosphate

European Journal of Oral Sciences, EarlyView.
Abstract This in vitro study evaluated the effect of a phosphomimetic statherin‐derived peptide (DDSt15), alone or combined with sodium trimetaphosphate (TMP), on the protection against initial enamel erosion. A total of 102 bovine enamel samples (4 × 4 mm2) were prepared and randomly allocated into six groups (n = 17): deionized water (negative ...
Carolina Ruis Ferrari, Hannah Zomignan Barros, Julia Pereira Bicalho, João Victor Frazão Câmara, Monique Malta Francese, Lethycia Almeida Santos, Juliano Pelim Pessan, Naiara Maia Pereira, Reinaldo Marchetto, Marília Afonso Rabelo Buzalaf   +9 more
wiley   +1 more source

Smooth Muscle Cell Plasticity as a Central Determinant of Plaque Stability. [PDF]

Curr Atheroscler Rep
Chen PY, Simons M.
europepmc   +1 more source

Comminuted fractures of the proximal phalanx in horses: A multicentre retrospective review

Equine Veterinary Education, EarlyView.
Summary Background Comminuted fractures of the proximal phalanx (CFPP), defined as the presence of three or more major fracture fragments, present difficult management challenges. Feedback from practitioners and long‐term follow‐up can be helpful to reassess evidence‐based treatment strategies and improve clinical outcomes.
C. de Chaisemartin, M. Farfan, B. Dal Cero, A. Martens, F. Rossignol, A. Kalinovskiy, C. Lischer, C. Tessier, S. Grulke, G. Manneveau, V. Gouzer, G. Gomez, J. Samsel, C. Mespoulhes‐Riviere, F. Pichereau, L. Alfonso Gracia Calvo, M. Trécu, A. Spadaro Rossello, P. Planes, X. Peyrecave, C. Mansuy, C. Henry‐Perin, A. Guezennec, M. C. Schramme   +23 more
wiley   +1 more source

SMC ensures efficient chromosome replication and oriC positioning during Streptomyces spore germination. [PDF]

Sci Rep
Pawlikiewicz K, Strzałka A, Nurek A, Donczew M, Gierlikowska A, Gongerowska-Jac M, Szafran MJ, Jakimowicz D.   +7 more
europepmc   +1 more source

Longitudinal actor–partner effects of emotion regulation difficulties on marital conflict and happiness in couples

Family Relations, EarlyView.
Abstract Objective This study used a longitudinal actor–partner interdependence model to investigate how couples' difficulties in emotion regulation affect their subjective happiness through marital conflict. Background Emotion regulation is central to marital quality and individual well‐being.
Yookyung Eoh, Jae Eun Lee, Ji Young Choi
wiley   +1 more source

Smc5/6 uses its head-NSE module to preferentially associate with ssDNA gaps and ss-dsDNA junctions. [PDF]

Nucleic Acids Res
Irvin EM, Park ST, Miller-Browne V, Lever R, Li S, Waterman G, Kaur P, Zhao X, Wang H.   +8 more
europepmc   +1 more source

The Impact of AI‐Assisted L2 Learning on Learners’ Emotions: A Meta‐Analysis

International Journal of Applied Linguistics, EarlyView.
ABSTRACT The scope of research on AI‐assisted second/foreign language (L2/FL) learning has expanded beyond learning outcomes to focus on learners’ emotional experiences. Despite their proliferation, existing empirical findings are inconsistent, and few studies have systematically synthesized the impacts of AI‐assisted L2 learning on learners’ emotional
Jiaqi Jing, Xinjie Chen, Timothy Teo, Ziwei Xiao, Nandini Agarwal   +4 more
wiley   +1 more source