Results 121 to 130 of about 16,449 (234)
An extrinsic motor directs chromatin loop formation by cohesin
The EMBO JournalThe ring-shaped cohesin complex topologically entraps two DNA molecules to establish sister chromatid cohesion. Cohesin also shapes the interphase chromatin landscape with wide-ranging implications for gene regulation, and cohesin is thought to achieve ...
Thomas M Guérin +4 more
doaj +1 more source
European Journal of Social Psychology, EarlyView.ABSTRACT Societal gender role norms play a crucial role in shaping men's and women's career aspirations. However, prior research documenting this key role of gendered norms has primarily focused on heterosexual women and men in the global North‐West. Previous studies documenting differences in career interests by sexual orientation suggest that gender ...
Katharina Block +136 more
wiley +1 more source
Energy Science &Engineering, EarlyView.The growing demand for electric vehicles (EVs) has driven research into improving propulsion control systems, focusing on performance, efficiency, and safety. This study addresses a gap in advanced control systems for EV differentials and presents two solutions.
Rachad Moumni +7 more
wiley +1 more source
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Objective This study examined the psychometric properties of the Edinburgh Postpartum Depression scale (EPDS) in a large‐scale community‐based perinatal sample in the Philippines. Methods This study involved a total of 1025 pregnant women (n = 356), postpartum women (n = 500), and women who experienced stillbirth or neonatal death (n = 169 ...
Arbie Diane Flores‐Davantes +13 more
wiley +1 more source
The Endothelial CXCR Family in Vascular Health and Disease
iNew Medicine, EarlyView.ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu +4 more
wiley +1 more source
iNew Medicine, EarlyView.ABSTRACT It is estimated that a large proportion of drug candidates fail in human clinical trials, mainly because animal models cannot fully replicate human disease and because of differential responses to various medications between humans and animals.
Weiping Ding, Iqra Ilyas, Suowen Xu
wiley +1 more source
Journal of Clinical Laboratory Analysis, EarlyView.Thoracic aortic aneurysm (TAA) is a life‐threatening cardiovascular disease with limited therapeutic options. Through single‐cell RNA sequencing of aortic tissues from healthy individuals and TAA patients (105,541 cells), we identified CLEC5A+macrophages as the predominant pathogenic cell population exhibiting the highest M1 polarization score. Machine
Xiangyu Li +3 more
wiley +1 more source
Land Degradation &Development, EarlyView.ABSTRACT Although numerous prediction methods have been developed, scientific estimation of the spatiotemporal pattern of soil erosion at the watershed scale remains challenging. In this study, fallout radionuclides of 210Pbex and 137Cs were used to estimate average annual soil erosion and deposition in a Mollisol watershed in Northeast China ...
Shaoliang Zhang +7 more
wiley +1 more source
Single‐Cell Transcriptomics and Deep Learning Link N‐(2‐Furoyl) Glycine to GLRX3 in Gastric Cancer
Med Research, EarlyView.ABSTRACT Gastric cancer remains a health burden, and its metabolic drivers are poorly defined. N‐(2‐furoyl) glycine, a circulating metabolite, has been implicated in tumor biology. We investigated its causal role in gastric cancer and the underlying mechanism.
Yingyi Zhang +4 more
wiley +1 more source
Predictive Assessment of Progressive Damage in Mechanically Fastened Glass–Epoxy Composites
Polymer Composites, EarlyView.Progressive damage in mechanically fastened glass–epoxy composites. ABSTRACT Ensuring the structural integrity of advanced composites necessitates precise methodologies for forecasting the onset and progression of damage. This research focused on the predicting progressive damage (PD) for riveted joints composite laminates employing a combined ...
Nabi Mehri Khansari +2 more
wiley +1 more source