Results 101 to 110 of about 16,909 (206)

An extrinsic motor directs chromatin loop formation by cohesin

The EMBO Journal
The ring-shaped cohesin complex topologically entraps two DNA molecules to establish sister chromatid cohesion. Cohesin also shapes the interphase chromatin landscape with wide-ranging implications for gene regulation, and cohesin is thought to achieve ...
Thomas M Guérin, Christopher Barrington, Georgii Pobegalov, Maxim I Molodtsov, Frank Uhlmann   +4 more
doaj   +1 more source

Psychometric properties of the Edinburgh postnatal depression scale in a large‐scale community‐based perinatal sample in the Philippines

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective This study examined the psychometric properties of the Edinburgh Postpartum Depression scale (EPDS) in a large‐scale community‐based perinatal sample in the Philippines. Methods This study involved a total of 1025 pregnant women (n = 356), postpartum women (n = 500), and women who experienced stillbirth or neonatal death (n = 169 ...
Arbie Diane Flores‐Davantes, Joyce Lisa Acena, Rebecca A. Guarino, Reinalyn Lim Cardenas, Charlene Joy Mendoza Sta. Maria, Angelica Villanueva Felipe, Mayla Rivera, Wilfredo Quijencio Jr., Pearl Angeline B. Pertubal, Rosemarie Quilala, Rachelle Sarmiento, Ana Nelia Jumamil, Joycelyn Abiog Filoteo, Joemer Calderon Maravilla   +13 more
wiley   +1 more source

The Endothelial CXCR Family in Vascular Health and Disease

iNew Medicine, EarlyView.
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu, Yandi Wu, Suowen Xu, Yu Huang, Li Wang   +4 more
wiley   +1 more source

Emerging Human‐Based Research Technologies for Investigating the Pathomechanisms and Therapies for Vascular Diseases

iNew Medicine, EarlyView.
ABSTRACT It is estimated that a large proportion of drug candidates fail in human clinical trials, mainly because animal models cannot fully replicate human disease and because of differential responses to various medications between humans and animals.
Weiping Ding, Iqra Ilyas, Suowen Xu
wiley   +1 more source

Integrating anaerobic and photochemical processes: UV–vis‐driven post‐treatment for micropollutant abatement and toxicity control in UASB secondary effluent

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Upflow anaerobic sludge blanket (UASB) reactors are widely used in low‐ and middle‐income countries, but secondary effluents may still contain organic micropollutants and residual toxicity. This study evaluated UV–Vis photolysis and UV/H2O2 as post‐treatment options for UASB secondary effluent (SE), integrating micropollutant ...
Fernando Rodrigues‐Silva, Gabriella P Masceno, Paloma P Panicio, Magno Lange Albuquerque, Rafaela Imoski, Wanessa A Ramsdorf, Liziê DT Prola, Maria Clara VM Starling, Camila C Amorim, Fernando H Passig, Marcus V Liz   +10 more
wiley   +1 more source

Patterns of psychopathology and personal strengths among youth in psychiatric care

JCPP Advances, EarlyView.
Abstract Background The American Academy of Pediatrics and the American Academy of Child and Adolescent Psychiatry have declared a National State of Emergency in Children's Mental Health, calling for improved approaches to address youth mental health.
Logan R. Cummings, Gil Noam, Alessandro S. De Nadai, Kathryn Parker, Patricia Allen, Julianne G. Wilner, Jillian M. Russo, Lauren O. Delman, Aishwarya Surendran, Emily G. Arnott, Dawn E. Sugarman, Alisa Busch, Alexander Kos, Fairlee C. Fabrett, Ralph Buonopane, Kristen L. Batejan, Erika C. Esposito, Tian Yu Cheng, Samuel J. Marquis, Wilson Giles Stecher, Caroline S. Abut, Fiona Ritchie, Jeffrey Zhang, Emily A. Hutchinson, Isabella Kahhale, Hannah Becker, Jennifer T. Sneider, Marisa M. Silveri, Colin W. Burke, Elan French, Esther S. Tung, Abigail M. Stark, Jennifer R. Klix, Anna B. Mazur, Denice E. Cronin, Kayla M. Turner, Melanie R. Harkins, Peter Adams, Willow Clayton, Clare Foster, Dorothea R. Volpp, Emily Gaddy, Florence R. Stout, Alyssa L. Faro, Maria G. Fraire, Mary Gambill, Perihan Esra Guvenek‐Cokol, Christopher Alpert, Cynthia Kaplan, Erin V. Batarseh, Gillian Galen, Kesley A. Hobbs, Lola M. Rodriguez, Lukas A. Turlick, Rhea Agrawal, Sophia E. Nadeau, Allison P. Falls, Eliot Fearey, Daniella H. Levy, Ana L. Ibarra, Bryan C. Pridgen, Julia G. Luppino, Kelly Molthrop, Louise J. Weidner, Munya Hayek, Kayla J. Saucedo, Magdalena S. Batlle, Payton B. Maclean, Rajvi Broker‐Sen, Wendy P. Bamatter, Charles Moore, Rachel L. Wallace, Rae‐Anna Muise, Tessa N. Hamilton, Jacqueline B. Sperling, Paulina Loo, R. Meredith Elkins, Michelle C. Silverman, Daniel P. Dickstein   +78 more
wiley   +1 more source

Optimized Fertilization Balances Microbial Carbon and Nitrogen Use Efficiency: Evidence From Microbial Communities

Land Degradation &Development, EarlyView.
ABSTRACT Optimized fertilization involving reduced mineral N input and organic substitution can alter resource stoichiometry, microbial carbon use efficiency (CUE) and nitrogen use efficiency (NUE). However, how fertilization‐induced resource imbalance reshapes microbial community to regulate CUE and NUE remains unclear. We conducted a field experiment
Yazhen Chen, Yichen Xu, Haobo Xu, Juan Chen, Xiaozhou Huang, Wenqiong Jiang, Jinsong He, Xiaohong Wu, Xinxing He, Jun Wang, Xiaocui Liang, Wende Yan   +11 more
wiley   +1 more source

Harnessing Aggregation‐Induced Emission for Advanced Disease Diagnosis: Mechanisms, Strategies and Future Perspectives

Medicine Bulletin, EarlyView.
The figure was created in BioRender.com. ABSTRACT Accurate and early diagnosis remains a key challenge in modern disease management. Conventional diagnostic methods often suffer from limitations in sensitivity, spatial resolution, and practical usability.
Zizhuo Du, Li Song, Xingrui Chen, Jun Jing, Yingchen Wang, Yue Jiang, Jiahui Gao, Dan Li, Feiran Xie, Peihong Xiao, Ben Zhong Tang   +10 more
wiley   +1 more source

Sleep‐Autonomic Interactions in Parkinson's Disease and Multiple System Atrophy: A Comparative Study Using Structural Equation Modeling

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Parkinson's disease (PD) and multiple system atrophy (MSA) are α‐synucleinopathies with overlapping autonomic and sleep dysfunction, but distinct trajectories. Objectives This study compared sleep and autonomic profiles in PD and MSA and elucidated disease‐specific associations using structural equation modeling (SEM).
Bora Jin, Yoonkyung Lee, Seungho Lee, Byeol‐A Yoon, Young Jin Jeong, Sang‐Myung Cheon   +5 more
wiley   +1 more source

Dynamic Performance Enhancement of a High‐Agility Hypersonic Mechanical System via a Learning‐Augmented Robust Control Architecture

International Journal of Mechanical System Dynamics, EarlyView.
ABSTRACT The design of control systems for high‐agility mechanical systems operating in extreme environments is a significant challenge in nonlinear dynamics. This paper addresses the complex dynamic control problem of a hypersonic interceptor, modeled as a multi‐input multi‐output (MIMO) mechanical system characterized by strong aerodynamic cross ...
Mohammad Mahdi Soori, Seyed Hossein Sadati   +1 more
wiley   +1 more source