Results 91 to 100 of about 8,854,464 (148)

Spatial Chromatin Organization Across the Cell Cycle: Insights from Auxin-Inducible Protein Depletion

Cells
Many cellular processes, including gene expression regulation, DNA replication and repair, as well as proper condensation and segregation of chromosomes, require highly coordinated remodeling of chromatin.
Artem Nurislamov, Anastasia Yunusova
doaj   +1 more source

SMC proteins and chromosome mechanics: from bacteria to humans

, 2005
Chromosome cohesion and condensation are essential prerequisites of proper segregation of genomes during mitosis and meiosis, and are supported by two structurally related protein complexes, cohesin and condensin, respectively.
Hirano, T.
core   +1 more source

Molecular mechanism of condensin I activation by KIF4A

The EMBO Journal
During mitosis, the condensin I and II complexes compact chromatin into chromosomes. Loss of the chromokinesin, KIF4A, results in reduced condensin I association with chromosomes, but the molecular mechanism behind this phenotype is unknown.
Erin E Cutts, Damla Tetiker, Eugene Kim, Luis Aragon   +3 more
doaj   +1 more source

원핵생물 콘덴신의 Smc 소단위체에 관한 구조적 연구

, 2018
학위논문(박사) - 한국과학기술원 : 생명과학과, 2018.2,[iv, 92 p. :]Structural Maintenance of Chromosome (SMC) complexes are involved in various cellular mechanisms that require chromosomal stability, such as regulation of chromosomal superstructure formation and chromosome
Lee, Hansol
core   +1 more source

A phospho-switch to trigger mitotic chromosome condensation

Biology Direct
One of the most eye-catching events in cell biology is the condensation of chromosomes. During mitosis, the diffuse interphase chromatin rearranges into compact, rod-shaped chromosomes that can be precisely segregated between the daughter cells.
Alessandro Borsellini
doaj   +1 more source

Condensin Architecture and Interaction with DNA Regulatory Non-SMC Subunits Bind to the Head of SMC Heterodimer

, 2002
Condensin and cohesin are two protein complexes that act as the central mediators of chromosome condensation and sister chromatid cohesion, respectively. The basic underlying mechanism of action of these complexes remained enigmatic. Direct visualization
Kohji Hizume, Yoshimura, Shige H., Takashi Sutani, Akiko Murakami, Kunio Takeyasu, Murakami, Akiko, Yanagida, Mitsuhiro, Hizume, Kohji, Mitsuhiro Yanagida, Sutani, Takashi, Shige H. Yoshimura, Takeyasu, Kunio   +11 more
core   +1 more source

An extrinsic motor directs chromatin loop formation by cohesin

The EMBO Journal
The ring-shaped cohesin complex topologically entraps two DNA molecules to establish sister chromatid cohesion. Cohesin also shapes the interphase chromatin landscape with wide-ranging implications for gene regulation, and cohesin is thought to achieve ...
Thomas M Guérin, Christopher Barrington, Georgii Pobegalov, Maxim I Molodtsov, Frank Uhlmann   +4 more
doaj   +1 more source

Analysis of the Chromosomal Localization of Yeast SMC Complexes by Chromatin Immunoprecipitation. [PDF]

Methods Mol Biol, 2019
Makrantoni V, Robertson D, Marston AL.
europepmc   +1 more source

Bridging-driven condensation by eukaryotic SMC complexes is a conserved feature of genome organization. [PDF]

Nucleic Acids Res
Jang JW, Higashi TL, Tang M, Kim C, Kinoshita Y, Myeong H, Lee J, Nishiyama T, Cho WK, Uhlmann F, Dekker C, Ryu JK.   +11 more
europepmc   +1 more source

Transcription-coupled recruitment of SMC complexes in yeast. [PDF]

FEMS Yeast Res
Kim JH, Chae YS, Kim KD.
europepmc   +1 more source