Results 91 to 100 of about 557,699 (363)

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

open access: yesMolecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad   +13 more
wiley   +1 more source

Data Smells: Categories, Causes and Consequences, and Detection of Suspicious Data in AI-based Systems [PDF]

open access: yesarXiv, 2022
High data quality is fundamental for today's AI-based systems. However, although data quality has been an object of research for decades, there is a clear lack of research on potential data quality issues (e.g., ambiguous, extraneous values). These kinds of issues are latent in nature and thus often not obvious.
arxiv  

On the Feasibility of Transfer-learning Code Smells using Deep Learning

open access: yes, 2019
Context: A substantial amount of work has been done to detect smells in source code using metrics-based and heuristics-based methods. Machine learning methods have been recently applied to detect source code smells; however, the current practices are ...
Efstathiou, Vasiliki   +3 more
core   +1 more source

Prevalence of Taste and Smell Dysfunction in Coronavirus Disease 2019.

open access: yesJAMA Otolaryngology - Head and Neck Surgery, 2020
Importance Early diagnosis of coronavirus disease 2019 (COVID-19) may help control the diffusion of the disease into the population. Objective To investigate the presence of sinonasal manifestations at the onset of COVID-19 to achieve an earlier ...
G. Mercante   +14 more
semanticscholar   +1 more source

Enhancing transporter activity in heterologous expression systems with SAHA: a 2500‐times more potent and odorless alternative to butyrate

open access: yesFEBS Open Bio, EarlyView.
Heterologous expression of membrane transporters in cultured cells is essential for functional characterization, but is sometimes limited by low activity. Our study compares the HDAC inhibitors butyrate, VPA and SAHA to enhance transport activity. We propose to replace butyrate by SAHA: it is equally effective, devoid of repulsive odor, costs less, and
Svenja Flögel   +4 more
wiley   +1 more source

Worst Smells and Their Worst Reasons [PDF]

open access: yesarXiv, 2021
The aims of this paper are: 1) to identify "worst smells", i.e., bad smells that never have a good reason to exist, 2) to determine the frequency, change-proneness, and severity associated with worst smells, and 3) to identify the "worst reasons", i.e., the reasons for introducing these worst smells in the first place.
arxiv  

Tractography indicates lateralized differences between trigeminal and olfactory pathways

open access: yesNeuroImage, 2022
Odorous sensations are based on trigeminal and olfactory perceptions. Both trigeminal and olfactory stimuli generate overlapping as well as distinctive activations in the olfactory cortex including the piriform cortex.
Divesh Thaploo   +4 more
doaj  

Shear Strength of Franciscan Complex Melange as Calculated from Back-Analysis of a Landslide [PDF]

open access: yes, 2004
A methodology was developed to evaluate causation of a complex landslide that occurred in Franciscan Complex melange during the winter of 1996-1997 in San Mateo County, California.
Kim, Carl   +2 more
core   +1 more source

Patterns of smell recovery in 751 patients affected by the COVID‐19 outbreak

open access: yesEuropean Journal of Neurology, 2020
Post‐viral olfactory dysfunction is well established and has been shown to be a key symptom of COVID‐19 with more than 66% of European and US patients reporting some degree of loss of smell.
C. Chiesa-Estomba   +6 more
semanticscholar   +1 more source

Enhanced discovery of bacterial laccase‐like multicopper oxidase through computer simulation and metagenomic analysis of industrial wastewater

open access: yesFEBS Open Bio, EarlyView.
We obtained potential bacterial laccase‐like multicopper oxidase (LMCO) sequences through metagenomic sequencing. All sequences exhibited significant differences from known LMCOs in databases. To select the most promising candidates, we performed structure prediction and molecular docking using alphafold2, metal3d and rosetta.
Ting Cui   +5 more
wiley   +1 more source

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