Results 71 to 80 of about 178,519 (305)

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Smell Above All: Envisioning Smell-Centred Future Worlds [PDF]

Take a deep breath; what do you smell? While sight and hearing dominate our perceptions, the sense of smell is often overlooked, even undervalued. However, the importance of our sense of smell goes beyond detecting odours.
Shabanova, Nonna, Maggioni, Emanuela, Boak, Duncan, Brianza, Giada, Philpott, Carl, Dawes, Christopher, Mathur, Sanjoli, Lechner, Matthias, Beşevli, Ceylan, Schieck, Ava Fatah Gen, Obrist, Marianna   +10 more
core   +2 more sources

Effects of nighttime odor exposure and delivery methods on subjective sleep quality in healthy adults

Scientific Reports
The role of smell in improving sleep quality is inconclusive. This study aimed to investigate whether the type of odor and the method of application affect sleep quality.
Zetian Li, Jean Christoph Gerami-Manesch, Lisa Marie Hoehnel, Jonathan Warr, Antje Haehner, Thomas Hummel   +5 more
doaj   +1 more source

Exploring the eradication of code smells: An empirical and theoretical perspective [PDF]

, 2010
This article has been made available through the Brunel Open Access Publishing Fund - Copyright @ 2010 Hindawi Publishing CorporationCode smells reflect code decay, and, as such, developers should seek to eradicate such smells through application of ...
H. Hamza, Durrand, M, M. Durrand, S. Black, Black, S, Counsell, S, Hierons, RM, Hamza, H, R. M. Hierons, S. Counsell   +9 more
core   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Ambient air pollution undermines chemosensory sensitivity – a global perspective

Scientific Reports
This study offers insights into the complex relationship between chemical species constituting air pollution and chemosensory function. We examined the relationship between chemical species known to contribute to air pollution and assault human health ...
Anna Oleszkiewicz, Andrea Pozzer, Jonathan Williams, Thomas Hummel   +3 more
doaj   +1 more source

Mashail8/Code-Smells: Code Smell Taxonomy Research Materials

<p>Code Smell Taxonomy Research Materials</p> <p>This repository contains the materials used in the research study "A Novel Taxonomy to Capture Code Smells Caused by Refactoring".</p> <p>Contents</p> <p>
Code Smell Dataset
core   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Identification and Quantification of Volatile Ramson-Derived Metabolites in Humans

Frontiers in Chemistry, 2018
Ramson (Allium ursinum) is known for its typical garlic-like aroma. Both ramson and garlic belong to the genus allium which is characterized by a high content of sulfurous compounds.
Laura Scheffler, Constanze Sharapa, Tayyaba Amar, Andrea Buettner, Andrea Buettner   +4 more
doaj   +1 more source

Short-Course Pentoxifylline Is Not Effective in Post-Traumatic Smell Loss: A Pilot Study

Ear, Nose & Throat Journal, 2020
It has been suggested that systemic pentoxifylline may be beneficial in the treatment of olfactory dysfunction. The postulated mechanism of action involves nonselective competitive phosphodiesterase inhibition, leading to increased intracellular cyclic ...
Katherine L. Whitcroft MBChB(Hons), MRCS, DOHNS, Volker Gudziol MD, Thomas Hummel MD   +2 more
doaj   +1 more source