Results 71 to 80 of about 158,325 (313)
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
Smell mapping Astor Place [PDF]
, 2017 Odours and opinions are the key components of a smellscape map, and New York has both in abundance. “Smellmap Astor Place”, commissioned by NYC Department of Transportation Art Summer Streets programming team, added curiosity and calculated contention to
McLean, K. +1 more
core
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Smell Map Narratives of Place—Paris [PDF]
, 2014 Human olfactory experience and perception of cities is often shared at the source of the smell but diverse in the places to which those smells transport the smeller. This note investigates the role of smell in our city experience with a specific focus on
Kate McLean
core
Relationship Between Nasal Trigeminal Receptor Expression and Trigeminal Sensitivity
OTO OpenAn intact intranasal trigeminal function is crucial for chemosensory and somatosensory perception, environmental irritation detection, and triggering protective reflexes. Accurately assessing intranasal trigeminal function is thus essential.
Akshita Joshi +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Cold Spring Harbor Symposia on Quantitative Biology, 1965 Experimental research into olfactive code, noting psychological and physiological analysis, suggesting specific chemically sensitive molecules ...
J Y, Lettvin, R C, Gesteland
openaire +2 more sources
FEBS Open Bio, EarlyView.In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
wiley +1 more source
Granulocyte Colony Stimulating Factor (G‐CSF) and Olfactory Function—A Clinical Pilot Study
Laryngoscope Investigative OtolaryngologyBackground Although the olfactory epithelium, including its neuronal cell line, has inherent regenerative potential, therapeutic options remain limited.
C. A. Hintschich +8 more
doaj +1 more source
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
FEBS Open Bio, EarlyView.Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source