Results 61 to 70 of about 559,643 (344)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Processing for obtaining good quality water from sewage [PDF]

open access: yes, 1975
Sewage treatment method incorporates aqueous slurry of activated carbon and ash. Process eliminates smell and greatly reduces amounts of solids requiring disposal.
Humphrey, M. F.
core   +1 more source

Light and smell stimulus protocol reduced negative frontal EEG asymmetry and improved mood [PDF]

open access: yes, 2017
Light and smell have both been shown to induce beneficial changes to human psychophysiology. Bright light therapy has been shown to have a positive impact on anxiety and depression and smell has also been shown to have positive effects on mood, stress ...
Bointon, Emma S   +7 more
core   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Clivus Rathke cleft cyst: case report of a rare disease and literature review [PDF]

open access: yesRhinology Online, 2018
Background: Rathke's cleft cysts (RCCs) are nonneoplastic epithelial lesions derived from true remnants of the embryological Rathke's pouch. They are commonly located in the sellar and suprasellar region and usually appear as an asymptomatic mass. Case:
Cristóbal Langdon   +4 more
doaj   +1 more source

Digital Smell: Toward Electrically Reproducing Artificial Smell Sensations

open access: yesIEEE Access, 2023
Artificially reproducing smell sensations, without using chemical odorants, would change the future multisensory internet experiences. This article presents a computer-controlled smell reproduction technology proposed for stimulating human olfactory ...
Kasun Karunanayaka   +2 more
doaj   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Mapping the Olfactory Brain: A Systematic Review of Structural and Functional Magnetic Resonance Imaging Changes Following COVID-19 Smell Loss

open access: yesBrain Sciences
Background: Olfactory dysfunction (OD)—including anosmia and hyposmia—is a common and often persistent outcome of viral infections. This systematic review consolidates findings from structural and functional MRI studies to explore how COVID-19 SARS-CoV-2-
Hanani Abdul Manan   +3 more
doaj   +1 more source

OSMODRAMA – Theatre for the Nose

open access: yesRivista di Estetica, 2021
Chemosensory communication as a form of time-based performing art has occurred in form of ideas in literary fiction and in occasional concepts of art or entertainment in the past. The history of patents on devices for such purposes since the beginning of
Wolfgang Georgsdorf
doaj   +1 more source

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