Results 41 to 50 of about 152,111 (264)
Smells-sus: Sustainability Smells in IaC
2025 IEEE/ACM 22nd International Conference on Mining Software Repositories (MSR)Practitioners use Infrastructure as Code (IaC) scripts to efficiently configure IT infrastructures through machine-readable definition files. However, during the development of these scripts, some code patterns or deployment choices may lead to sustainability issues like inefficient resource utilization or redundant provisioning for example.
Seif Kosbar, Mohammad Hamdaqa
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Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
Cold Spring Harbor Symposia on Quantitative Biology, 1965 Experimental research into olfactive code, noting psychological and physiological analysis, suggesting specific chemically sensitive molecules ...
J Y, Lettvin, R C, Gesteland
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Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Smellmap : Amsterdam - olfactory art & smell visualisation [PDF]
, 2016 Creating a smellmap of a city is a subjective, collaborative exer-cise. During a series of smellwalks local participants foreground their sense of smell and name perceived aromas emanating from the urban smellscape.
McLean, K.
core
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Clinical Diabetes, 2018 In my everyday job as a research director, I work with endocrine fellows and staff on research. And because I have had type 1 diabetes since 1992, I also subtly look for teachable moments to promote a greater understanding about what it is like to live with diabetes.
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FEBS Open Bio, EarlyView.In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
wiley +1 more source