Results 11 to 20 of about 885,158 (358)
Bindarit inhibits human coronary artery smooth muscle cell proliferation, migration and phenotypic switching. [PDF]
PLoS ONE, 2012 Bindarit, a selective inhibitor of monocyte chemotactic proteins (MCPs) synthesis, reduces neointimal formation in animal models of vascular injury and recently has been shown to inhibit in-stent late loss in a placebo-controlled phase II clinical trial.
Marcella Maddaluno +11 more
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Rare giant perianal smooth muscle tumor: A case report [PDF]
Journal of International Medical ResearchSmooth muscle tumors are benign tumors originating from smooth muscle tissues, mostly occurring in the uterus and digestive tract; however, smooth muscle tumors occurring in the perianal sphincter are very rare.
Yuanchao Guo +7 more
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ANO1 channels are expressed in mouse urethral smooth muscle but do not contribute to agonist or neurally evoked contractions [PDF]
Scientific ReportsAnoctamin-1 Ca2+-activated Cl− channels (ANO1) are proposed to modulate contractility of urethra smooth muscle cells (USMC), but their cellular expression and contribution to agonist/neural evoked activity is unclear.
Neha Gupta +10 more
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The extracellular signal-regulated kinase (ERK) pathway: a potential therapeutic target in hypertension [PDF]
Journal of Experimental Pharmacology, 2012 Richard E RobertsSchool of Biomedical Sciences, University of Nottingham, Nottingham, United KingdomAbstract: Hypertension is a risk factor for myocardial infarction, stroke, renal failure, heart failure, and peripheral vascular disease.
Roberts RE
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Physiological Reports, 2022 Penile detumescence is maintained by tonic contraction of corpus cavernosum smooth muscle cells (CCSMC), but the underlying mechanisms have not been fully elucidated.
Xin Rui Lim +4 more
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Congenital smooth muscle hamartoma [PDF]
Anais Brasileiros de Dermatologia, 2019 Luana Rocco Pereira Copi +3 more
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Defining smooth muscle cells and smooth muscle injury [PDF]
Journal of Clinical Investigation, 2005 For 3 decades, terms such as synthetic phenotype and contractile phenotype have been used to imply the existence of a specific mechanism for smooth muscle cell (SMC) responses to injury. In this issue of the JCI, Hendrix et al. offer a far more precise approach to examining the mechanisms of SMC responses to injury, focused not on general changes in ...
Stephen M. Schwartz, William M. Mahoney
openaire +3 more sources
Sepsis downregulates aortic Notch signaling to produce vascular hyporeactivity in mice
Scientific Reports, 2022 Inhibition of Notch signaling in macrophages is known to reduce inflammation, however, its role in regulating vascular hyporeactivity in sepsis is unknown. Thus we aimed to evaluate the effect of sepsis on vascular Notch signaling.
Vandana Singh +8 more
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Characterization of Cecal Smooth Muscle Contraction in Laying Hens
Veterinary Sciences, 2021 The ceca play an important role in the physiology of the gastrointestinal tract in chickens. Nevertheless, there is a gap of knowledge regarding the functionality of the ceca in poultry, especially with respect to physiological cecal smooth muscle ...
Katrin Röhm +3 more
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Smooth muscle strips for intestinal tissue engineering. [PDF]
PLoS ONE, 2014 Functionally contracting smooth muscle is an essential part of the engineered intestine that has not been replicated in vitro. The purpose of this study is to produce contracting smooth muscle in culture by maintaining the native smooth muscle ...
Christopher M Walthers +3 more
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