Results 51 to 60 of about 470,782 (316)

Smooth muscle hyperplasia of the epididymis [PDF]

Journal of Surgical Case Reports, 2011
Benign smooth muscle cell proliferation commonly involves a variety of body organs, yet is a rare finding in the spermatic cord or paratesticular tissue of the male genital tract. Here we discuss a case of smooth muscle hyperplasia of the epididymis which presented as an intrascrotal mass.
Anne Marie Pollock, D Douglas, O Blach
openaire   +3 more sources

Airway Smooth Muscle and Asthma

Cells, 2023
Airway smooth muscle (ASM) was first described in 1804 by Franz Daniel Reisseisen (as related by Otis (1983)) [...]
Steven An, Dale D. Tang
openaire   +3 more sources

Discovery and Treatment of Action Potential‐Independent Myotonia in Hyperkalemic Periodic Paralysis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hyperkalemic periodic paralysis (hyperKPP) is characterized by attacks of transient weakness. A subset of hyperKPP patients suffers from transient involuntary contraction of muscle (myotonia). The goal of this study was to determine mechanisms causing myotonia in hyperKPP.
Chris Dupont, Adam Deardorff, Murad Nawaz, Andrew A. Voss, Mark M. Rich   +4 more
wiley   +1 more source

Digital Activity Markers in Chronic Inflammatory Demyelinating Polyneuropathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the utility of smartwatch and smartphone‐based activity metrics for assessing disease severity and quality of life in patients with chronic inflammatory demyelinating polyneuropathy (CIDP). Methods In the electronic monitoring of disease activity in patients with CIDP (EMDA‐CIDP) trial, we performed a prospective ...
Lars Masanneck, Jan Voth, Noëmi Gmahl, Konstantin Jendretzky, Niklas Huntemann, Noah M. Werner, Linea Schmidt, Menekse Oeztuerk, Paula Quint, Christina B. Schroeter, Hans Peter Hartung, Thomas Skripuletz, Gerd Meyer zu Hörste, Tobias Ruck, Sven G. Meuth, Marc Pawlitzki   +15 more
wiley   +1 more source

Physiology and Pathophysiology of Proteinase-Activated Receptors (PARs): Proteinases as Hormone-Like Signal Messengers: PARs and More

Journal of Pharmacological Sciences, 2005
Proteinases like thrombin and trypsin, long known for their ability to activate the coagulation cascade or to act as digestive enzymes for many protein targets, are now recognized as hormone-like regulators of cell function.
Morley D. Hollenberg
doaj  

Role and regulation of Abelson tyrosine kinase in Crk-associated substrate/profilin-1 interaction and airway smooth muscle contraction

Respiratory Research, 2018
Background Airway smooth muscle contraction is critical for maintenance of appropriate airway tone, and has been implicated in asthma pathogenesis. Smooth muscle contraction requires an “engine” (myosin activation) and a “transmission system” (actin ...
Yinna Wang, Alyssa C. Rezey, Ruping Wang, Dale D. Tang   +3 more
doaj   +1 more source

CREB depletion in smooth muscle cells promotes medial thickening, adventitial fibrosis and elicits pulmonary hypertension

Pulmonary Circulation, 2020
Levels of the cAMP-responsive transcription factor, CREB, are reduced in medial smooth muscle cells in remodeled pulmonary arteries from hypertensive calves and rats with chronic hypoxia-induced pulmonary hypertension.
Chrystelle V. Garat, Susan M. Majka, Timothy M. Sullivan, Joseph T. Crossno, Jane E.B. Reusch, Dwight J. Klemm   +5 more
doaj   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

Biochemical Properties of a Bushmaster Snake Venom Serine Proteinase (LV-Ka), and Its Kinin Releasing Activity Evaluated in Rat Mesenteric Arterial Rings

Journal of Pharmacological Sciences, 2004
A serine proteinase with kallikrein-like activity (LV-Ka) has been purified to homogeneity from bushmaster snake (Lachesis muta muta) venom. Physicochemical studies indicated that LV-Ka is a single chain glycoprotein with a molecular mass (Mr) of 33 kDa ...
Maria L.D. Weinberg, Liza F. Felicori, Cynthia A. Bello, Henrique P.B. Magalhães, Alvair P. Almeida, Arinos Magalhães, Eladio F. Sanchez   +6 more
doaj  

Cyclic Mechanical Stretch Induced Smooth Muscle Cell Changes in Cerebral Aneurysm Progress by Reducing Collagen Type IV and Collagen Type VI Levels

Cellular Physiology and Biochemistry, 2018
Background/Aims: Cerebral aneurysm growth is characterized by continuous structural weakness of local smooth muscle cells, though the mechanism is unclear.
Peixi Liu, Yaying Song, Yingjie Zhou, Yingjun Liu, Tianming Qiu, Qingzhu An, Jianping Song, Peiliang Li, Yuan Shi, Sichen Li, Kai Quan, Guo-Yuan Yang, Wei Zhu   +12 more
doaj   +1 more source