Results 21 to 30 of about 6,895,201 (344)

Retinoids and Arterial Smooth Muscle Cells [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2000
Retinoic acid (RA), the active metabolite of vitamin A, is a crucial signaling molecule during vertebrate development and plays key roles in establishing cell lineages as well as in cell differentiation and proliferation.1 RA has been shown to influence the expression of many genes ( see the Table⇓ ) through interactions between RA receptors (RARs) and
Neuville, P., Bochaton-Piallat, Marie-Luce, Gabbiani, Giulio   +2 more
openaire   +4 more sources

Bindarit inhibits human coronary artery smooth muscle cell proliferation, migration and phenotypic switching [PDF]

, 2012
Bindarit, a selective inhibitor of monocyte chemotactic proteins (MCPs) synthesis, reduces neointimal formation in animal models of vascular injury and recently has been shown to inhibit in-stent late loss in a placebo-controlled phase II clinical trial.
DI LAURO M. V., Maria Vittoria Di Lauro (127364), Teresa Iuvone (127378), Angelo Guglielmotti, Angelo Guglielmotti (127381), Pasquale Maffia (127384), Gianluca Grassia (127362), Cicala, C., MADDALUNO, MARCELLA, Francesco Maione, Maria Vittoria Di Lauro, Nicola Mascolo, Nicola Mascolo (127387), Maffia, P., Gianluca Grassia, Armando Ialenti, Antonio Parisi (127365), GRASSIA, GIANLUCA, Guglielmotti, A., IALENTI, ARMANDO, Grassia, G., IUVONE, TERESA, MASCOLO, NICOLA DOMENICO C. FERDINANDO, Carla Cicala (127370), Pasquale Maffia, MAIONE, FRANCESCO, Maione, F., Iuvone, T., Maddaluno, M., GUGLIELMOTTI A., Daniele De Filippis (127374), De Filippis, D., Antonio Parisi, Carla Cicala, Armando Ialenti (127390), Ialenti, A., Parisi, A., CICALA, CARLA, MAFFIA, PASQUALE, Marcella Maddaluno (127360), Marcella Maddaluno, Teresa Iuvone, PARISI A., Mascolo, N., Francesco Maione (127366), Di Lauro, M.V., Daniele De Filippis, DE FILIPPIS, DANIELE   +47 more
core   +1 more source

Atheroprotective roles of smooth muscle cell phenotypic modulation and the TCF21 disease gene as revealed by single-cell analysis

Nature Medicine, 2019
In response to various stimuli, vascular smooth muscle cells (SMCs) can de-differentiate, proliferate and migrate in a process known as phenotypic modulation.
Robert C. Wirka, Dhananjay Wagh, David T. Paik, M. Pjanić, Trieu Nguyen, Clint L. Miller, R. Kundu, M. Nagao, J. Coller, Tiffany K. Koyano, Robyn Fong, Y. Woo, Boxiang Liu, S. Montgomery, Joseph C. Wu, Kuixi Zhu, Rui Chang, Melissa Alamprese, M. Tallquist, J. Kim, T. Quertermous   +20 more
semanticscholar   +1 more source

Regulation and characteristics of vascular smooth muscle cell phenotypic diversity

Netherlands Heart Journal, 2007
P A F M Doevendans
exaly   +2 more sources

Nitric Oxide Production and Smooth Muscle Cell Phenotype of Endothelial Cell-Smooth Muscle Cell Cocultured Model

Journal of Biomechanical Science and Engineering, 2006
This study investigated nitric oxide (NO) production and phenotype changes of smooth muscle cells (SMC) in a cocultured model (CM) exposed to fluid shear stress. The CM was composed of human umbilical endothelial cells (EC) and SMC, a collagen layer, and
Naoya SAKAMOTO, Masaki OI, Toshiro OHASHI, Masaaki SATO   +3 more
doaj   +1 more source

Vascular Smooth Muscle Cells [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2016
Decades of work have shown that vascular smooth muscle cell (SMC) phenotypes are controlled by cues received from the local environment.1–3 When nestled into a cage of cross-linked collagen and elastin of its own making,4 medial SMCs exhibit a fully differentiated phenotype conferred by the transcriptional activity of myocardin and serum response ...
openaire   +2 more sources

Smooth muscle cells largely develop independently of functional hemogenic endothelium

Stem Cell Research, 2014
Vascular smooth muscle cells represent a major component of the cardiovascular system. In vitro studies have shown that FLK1+ cells derived from embryonic stem (ES) cells can differentiate into both endothelial and smooth muscle cells.
Monika Stefanska, Guilherme Costa, Michael Lie-a-Ling, Valerie Kouskoff, Georges Lacaud   +4 more
doaj   +1 more source

Endothelial platelet-derived growth factor-mediated activation of smooth muscle platelet-derived growth factor receptors in pulmonary arterial hypertension

Pulmonary Circulation, 2020
Platelet-derived growth factor is one of the major growth factors found in human and mammalian serum and tissues. Abnormal activation of platelet-derived growth factor signaling pathway through platelet-derived growth factor receptors may contribute to ...
Kang Wu, Haiyang Tang, Ruizhu Lin, Shane G. Carr, Ziyi Wang, Aleksandra Babicheva, Ramon J. Ayon, Pritesh P. Jain, Mingmei Xiong, Marisela Rodriguez, Shamin Rahimi, Francesca Balistrieri, Shayan Rahimi, Daniela Valdez-Jasso, Tatum S. Simonson, Ankit A. Desai, Joe G.N. Garcia, John Y.-J. Shyy, Patricia A. Thistlethwaite, Jian Wang, Ayako Makino, Jason X.-J. Yuan   +21 more
doaj   +1 more source

Cell cultures of human ciliary muscle: growth, ultrastructural and immunocytochemical characteristics [PDF]

, 1991
Primary ciliary muscle cell cultures derived from human donors (16-91 years) were established and characterized by comparing them with ciliary muscle in tissue sections using immunocytochemical and ultrastructural methods.
Baur, A., Tamm, Ernst R., Flügel, C., Lütjen-Drecoll, E.   +3 more
core   +1 more source

Smooth Muscle Cell phenotypic diversity

Arteriosclerosis, Thrombosis and Vascular Biology, 2019
Vascular smooth muscle cells (SMC) play a critical role in controlling blood pressure and blood distribution, as well as maintaining the structural integrity of the blood vessel.
Mingjun Liu, D. Gomez
semanticscholar   +1 more source