Results 1 to 10 of about 654,799 (194)
Bindarit inhibits human coronary artery smooth muscle cell proliferation, migration and phenotypic switching. [PDF]
PLoS ONE, 2012 Bindarit, a selective inhibitor of monocyte chemotactic proteins (MCPs) synthesis, reduces neointimal formation in animal models of vascular injury and recently has been shown to inhibit in-stent late loss in a placebo-controlled phase II clinical trial.
Marcella Maddaluno +11 more
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Specialized mouse embryonic stem cells for studying vascular development [PDF]
Stem Cells and Cloning: Advances and Applications, 2014 Drew E Glaser,1 Andrew B Burns,2 Rachel Hatano,2 Magdalena Medrzycki,3 Yuhong Fan,3 Kara E McCloskey1 1School of Engineering, University of California, Merced, CA, USA; 2School of Natural Sciences, University of California, Merced, CA, USA; 3School of ...
Glaser DE +5 more
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Role of smooth muscle progenitor cells in vascular mechanical injury and repair
Medicine in Novel Technology and Devices, 2022 Smooth muscle progenitor cells are precursor cells that express both smooth muscle cell and stem cell markers, and can differentiate into smooth muscle cells under specific condition.
Zhu-feng Dong +7 more
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Circulation Research, 2000 Severe clinical manifestations of atherosclerosis, including sudden death, myocardial infarction, and stroke, mainly result from atherosclerotic plaque rupture/erosion that triggers thrombus formation, leading to occlusion of the vessel lumen.1 The occluding thrombus is mixed in nature and contains significant quantities of fibrin in addition to ...
Alain Tedgui, Ziad Mallat
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Smooth muscle strips for intestinal tissue engineering. [PDF]
PLoS ONE, 2014 Functionally contracting smooth muscle is an essential part of the engineered intestine that has not been replicated in vitro. The purpose of this study is to produce contracting smooth muscle in culture by maintaining the native smooth muscle ...
Christopher M Walthers +3 more
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Majalah Obstetri dan Ginekologi, 2021 HIGHLIGHT 1. Pain intensity, smooth muscle cells density, and alpha-SMA expression can be used to analyze the role of smooth muscle in endometriosis. 2.
Sutrisno Sutrisno +2 more
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Defining smooth muscle cells and smooth muscle injury [PDF]
Journal of Clinical Investigation, 2005 For 3 decades, terms such as synthetic phenotype and contractile phenotype have been used to imply the existence of a specific mechanism for smooth muscle cell (SMC) responses to injury. In this issue of the JCI, Hendrix et al. offer a far more precise approach to examining the mechanisms of SMC responses to injury, focused not on general changes in ...
William M, Mahoney, Stephen M, Schwartz
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Smooth muscle stem cells [PDF]
The Anatomical Record Part A: Discoveries in Molecular, Cellular, and Evolutionary Biology, 2003 AbstractVascular smooth muscle cells (SMCs) originate from multiple types of progenitor cells. In the embryo, the most well studied SMC progenitor is the cardiac neural crest stem cell. Smooth muscle differentiation in the neural crest lineage is controlled by a combination of cell intrinsic factors, including Pax3, Tbx1, FoxC1, and serum response ...
Karen K, Hirschi, Mark W, Majesky
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EPAC in Vascular Smooth Muscle Cells [PDF]
International Journal of Molecular Sciences, 2020 Vascular smooth muscle cells (VSMCs) are major components of blood vessels. They regulate physiological functions, such as vascular tone and blood flow. Under pathological conditions, VSMCs undergo a remodeling process known as phenotypic switching. During this process, VSMCs lose their contractility and acquire a synthetic phenotype, where they over ...
Nadine Wehbe +9 more
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Long non-coding RNAs: Modulators of phenotypic transformation in vascular smooth muscle cells
Frontiers in Cardiovascular Medicine, 2022 Long non-coding RNA (lncRNAs) are longer than 200 nucleotides and cannot encode proteins but can regulate the expression of genes through epigenetic, transcriptional, and post-transcriptional modifications.
Bing-Han Lu +16 more
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