Results 231 to 240 of about 18,655 (253)

Discovery of NVP-LDE225, a Potent and Selective Smoothened Antagonist

ACS Medicinal Chemistry Letters, 2010
Tove Tuntland, Xu Wu, Yongqin Wan
exaly  

Cholesterol Modification of Smoothened Is Required for Hedgehog Signaling

Molecular Cell, 2017
Lei Yin, Wen-Wei Qiu
exaly  

Targeting the Sonic Hedgehog Signaling Pathway: Review of Smoothened and GLI Inhibitors

Cancers, 2016
Carpenter R L, Hui-Wen Lo, Michael Chan   +2 more
exaly  

Discovery of PF-04449913, a Potent and Orally Bioavailable Inhibitor of Smoothened

ACS Medicinal Chemistry Letters, 2012
Qifang Li
exaly  

Sonic Hedgehog Activates Phospholipase A2 to Enhance Smoothened Ciliary Translocation

Cell Reports, 2017
Charles ROCK, Stacey K Ogden, Matthew Frank   +2 more
exaly  

Genetic and Epigenetic Regulation of the Smoothened Gene (SMO) in Cancer Cells

Cancers, 2020
Hongchuan Li, Stephen K Anderson, Andrew Huehn   +2 more
exaly  

Gli2 trafficking links Hedgehog-dependent activation of Smoothened in the primary cilium to transcriptional activation in the nucleus

Proceedings of the National Academy of Sciences of the United States of America, 2009
Philip Beachy, Jynho Kim, Beachy Philip A   +2 more
exaly  

Rapid, direct activity assays for Smoothened reveal Hedgehog pathway regulation by membrane cholesterol and extracellular sodium

Proceedings of the National Academy of Sciences of the United States of America, 2017
Benjamin Myers, Philip Beachy, Yunxiao Zhang   +2 more
exaly  

Overcoming the Emerging Drug Resistance of Smoothened: An Overview of Small-Molecule SMO Antagonists with Antiresistance Activity

Future Medicinal Chemistry, 2018
Zhaopeng Liu
exaly  

Vertebrate smoothened proteins

1998
DE SAUVAGE FREDERIC J, ROSENTHAL ARNON, STONE DONNA M   +2 more
openaire   +4 more sources