Results 231 to 240 of about 41,949 (243)

Discovery of NVP-LDE225, a Potent and Selective Smoothened Antagonist

ACS Medicinal Chemistry Letters, 2010
Xu Wu, Tove Tuntland
exaly  

Smoothened Variants Explain the Majority of Drug Resistance in Basal Cell Carcinoma

Cancer Cell, 2015
Scott X Atwood, Kavita Y Sarin, Jinah Kim   +2 more
exaly  

Rapid, direct activity assays for Smoothened reveal Hedgehog pathway regulation by membrane cholesterol and extracellular sodium

Proceedings of the National Academy of Sciences of the United States of America, 2017
Benjamin R Myers, Lila Neahring, Yunxiao Zhang   +2 more
exaly  

Cholesterol Modification of Smoothened Is Required for Hedgehog Signaling

Molecular Cell, 2017
Xu Xiao, Chao Peng, Yan Wang
exaly  

Hedgehog regulates smoothened activity by inducing a conformational switch

Nature, 2007
Yun Zhao, Chao Tong, Jin Jiang
exaly  

Sonic Hedgehog Activates Phospholipase A2 to Enhance Smoothened Ciliary Translocation

Cell Reports, 2017
Matthew W Frank, Stacey K Ogden
exaly  

BRAF; smoothened (SMO)

Science-Business eXchange, 2014
openaire   +1 more source

Cholesterol Interaction Sites on the Transmembrane Domain of the Hedgehog Signal Transducer and Class F G Protein-Coupled Receptor Smoothened

Structure, 2019
George Hedger, Heidi Koldsø, Matthieu Chavent   +2 more
exaly  

Hedgehog Induces Opposite Changes in Turnover and Subcellular Localization of Patched and Smoothened

Cell, 2000
exaly  

Smoothening leadership succession

2016
openaire   +1 more source