Results 41 to 50 of about 173,214 (325)

Detection of Snake Venom in Post-Antivenom Samples by Dissociation Treatment Followed by Enzyme Immunoassay

Toxins, 2016
Venom detection is crucial for confirmation of envenomation and snake type in snake-bite patients. Enzyme immunoassay (EIA) is used to detect venom, but antivenom in samples prevents venom detection.
Kalana P. Maduwage, Margaret A. O’Leary, Anjana Silva, Geoffrey K. Isbister   +3 more
doaj   +1 more source

A Contemporary Exploration of Traditional Indian Snake Envenomation Therapies

Tropical Medicine and Infectious Disease, 2022
Snakebite being a quick progressing serious situation needs immediate and aggressive therapy. Snake venom antiserum is the only approved and effective treatment available, but for selected snake species only.
Adwait M. Deshpande, K. Venkata Sastry, Satish B. Bhise   +2 more
doaj   +1 more source

Predicting antibacterial activity from snake venom proteomes.

PLoS ONE, 2020
The continued evolution of antibiotic resistance has increased the urgency for new antibiotic development, leading to exploration of non-traditional sources.
Justin L Rheubert, Michael F Meyer, Raeshelle M Strobel, Megan A Pasternak, Robert A Charvat   +4 more
doaj   +1 more source

Purification of a fragment obtained by autolysis of a PIIIb-SVMP from Bothrops alternatus venom [PDF]

, 2018
Snake Venom Metalloproteinases (SVMPs) represent 43.1% of the components in Bothrops alternatus venom and play an important role in envenomation. Disintegrins and disintegrin-like domains are released by proteolytic processing of PII and PIII classes of ...
Acosta, Ofelia Cristina, Biscoglio, Mirtha Josefa, Bustillo, Soledad, dos Santos, Patty Karina, Gay, Claudia Carolina, Leiva, Laura Cristina Ana, Olivera Moritz, Milene Nobrega de, Rodríguez, Juan Pablo, Sobreiro Selistre de Araujo, Heloisa, Van de Velde, Andrea Carolina   +9 more
core   +1 more source

Toxin expression in snake venom evolves rapidly with constant shifts in evolutionary rates

Proceedings of the Royal Society B, 2020
Key innovations provide ecological opportunity by enabling access to new resources, colonization of new environments, and are associated with adaptive radiation.
A. Barua, Alexander S. Mikheyev
semanticscholar   +1 more source

Snakes on a plain: biotic and abiotic factors determine venom compositional variation in a wide-ranging generalist rattlesnake

BMC Biology, 2023
Background Snake venoms are trophic adaptations that represent an ideal model to examine the evolutionary factors that shape polymorphic traits under strong natural selection.
Cara F. Smith, Zachary L. Nikolakis, Kathleen Ivey, Blair W. Perry, Drew R. Schield, Neil R. Balchan, Joshua Parker, Kirk C. Hansen, Anthony J. Saviola, Todd A. Castoe, Stephen P. Mackessy   +10 more
doaj   +1 more source

Antivenom Cross-Neutralization of the Venoms of Hydrophis schistosus and Hydrophis curtus, Two Common Sea Snakes in Malaysian Waters [PDF]

, 2015
Sea snake envenomation is a serious occupational hazard in tropical waters. In Malaysia, the beaked sea snake (Hydrophis schistosus, formerly known as Enhydrina schistosa) and the spine-bellied sea snake (Hydrophis curtus, formerly known as Lapemis ...
Choo, Hock Tan, Kae, Yi Tan, Kok, Onn Kwong, Nget, Hong Tan   +3 more
core   +1 more source

Size Matters: An Evaluation of the Molecular Basis of Ontogenetic Modifications in the Composition of Bothrops jararacussu Snake Venom

Toxins, 2020
Ontogenetic changes in venom composition have been described in Bothrops snakes, but only a few studies have attempted to identify the targeted paralogues or the molecular mechanisms involved in modifications of gene expression during ontogeny.
L. Freitas-de-Sousa, P. G. Nachtigall, J. A. Portes-Junior, M. Holding, G. Nystrom, S. A. Ellsworth, Noranathan C Guimarães, E. Tioyama, Flora Ortiz, Bruno R Silva, T. Kunz, I. Junqueira-de-Azevedo, F. Grazziotin, D. Rokyta, A. Moura-da-Silva   +14 more
semanticscholar   +1 more source

Snake venom toxin from vipera lebetina turanica induces apoptosis of colon cancer cells via upregulation of ROS- and JNK-mediated death receptor expression

BMC Cancer, 2012
Background Abundant research suggested that the cancer cells avoid destruction by the immune system through down-regulation or mutation of death receptors.
Park Mi, Jo MiRan, Won Dohee, Song Ho, Han Sang, Song Min, Hong Jin   +6 more
doaj   +1 more source

Reappraisal of Vipera aspis venom neurotoxicity. [PDF]

PLoS ONE, 2007
BACKGROUND: The variation of venom composition with geography is an important aspect of intraspecific variability in the Vipera genus, although causes of this variability remain unclear.
Elisabeth Ferquel, Luc de Haro, Virginie Jan, Isabelle Guillemin, Sabine Jourdain, Alexandre Teynié, Jacques d'Alayer, Valérie Choumet   +7 more
doaj   +1 more source