Results 111 to 120 of about 51,201 (249)

Mechanisms underpinning the permanent muscle damage induced by snake venom metalloprotease [PDF]

, 2019
Snakebite is a major neglected tropical health issue that affects over 5 million people worldwide resulting in around 1.8 million envenomations and 100,000 deaths each year.
Bicknell, Andrew, Collins-Hooper, Henry, Layfield, Harry, Matsakas, Antonios, Mellows, Ben, Mitchell, Robert, Patel, Ketan, Salamah, Maryam, Sfyri, Peggy, Vaiyapuri, Raj, Vaiyapuri, Sakthi, Williams, Harry   +11 more
core   +3 more sources

Treatment response and clinical features of snakebite envenomation in Alborz province, Iran: A cross‐sectional study

Health Science Reports, Volume 7, Issue 10, October 2024.
Abstract Background Snakebite envenomation is a significant yet neglected public health burden. Our aim was to investigate the clinical and demographic factors of snakebite envenomation, as well as the factors associated with its severity and response to treatment, in Alborz province, northern Iran. Methods In this cross‐sectional study, we included 50
Hoorvash Farajidana, Seyedarad Mosalamiaghili, Kasra Assadian, Soodeh Jahangiri, Maryam Masumzadegan, Farangis Sadeghi, Lida shojaei Arani   +6 more
wiley   +1 more source

Novel Catalytically-Inactive PII Metalloproteinases from a Viperid Snake Venom with Substitutions in the Canonical Zinc-Binding Motif

Toxins, 2016
Snake venom metalloproteinases (SVMPs) play key biological roles in prey immobilization and digestion. The majority of these activities depend on the hydrolysis of relevant protein substrates in the tissues.
Erika Camacho, Libia Sanz, Teresa Escalante, Alicia Pérez, Fabián Villalta, Bruno Lomonte, Ana Gisele C. Neves-Ferreira, Andrés Feoli, Juan J. Calvete, José María Gutiérrez, Alexandra Rucavado   +10 more
doaj   +1 more source

Transcriptome and venom proteome of the box jellyfish Chironex fleckeri [PDF]

, 2015
Background: The box jellyfish, Chironex fleckeri, is the largest and most dangerous cubozoan jellyfish to humans. It produces potent and rapid-acting venom and its sting causes severe localized and systemic effects that are potentially life-threatening ...
Brinkman, Diane L., Dash, Debasis, Jia, Xinying, Kumar, Dhirendra, Kvaskoff, David, Mulvenna, Jason, Potriquet, Jeremy   +6 more
core   +1 more source

Identification of accelerated evolution in the metalloproteinase domain of snake venom metalloproteinase sequences (SVMPs) through comparative analysis

, 2016
Computational protein sequence analysis is one of the most important tools used for understanding the evolution of closely related proteins sequences including snake venom metalloproteinase sequences (SVMPs) which give valuable information regarding ...
Mahmudul Islam, Z. Y. Roly, M. Ruhullah, Zohorul Islam, Alsan Sharia, Rafsan Zani Tanvir, Khaja Foyasal   +6 more
semanticscholar   +1 more source

Therapeutic Plasma Exchange to Reverse Plasma Failure in Multiple Organ Dysfunction Syndrome

Journal of Clinical Apheresis, Volume 39, Issue 5, October 2024.
ABSTRACT Plasma plays a crucial role in maintaining health through regulating coagulation and inflammation. Both are essential to respond to homeostatic threats such as traumatic injury or microbial infection; however, left unchecked, they can themselves cause damage.
Matthew J. Foglia, Jay S. Raval, Jan C. Hofmann, Joseph A. Carcillo   +3 more
wiley   +1 more source

Transcriptome analysis of Deinagkistrodon acutus venomous gland focusing on cellular structure and functional aspects using expressed sequence tags

BMC Genomics, 2006
Background The snake venom gland is a specialized organ, which synthesizes and secretes the complex and abundant toxin proteins. Though gene expression in the snake venom gland has been extensively studied, the focus has been on the components of the ...
Qiu Pengxin, Luo Yingfeng, Huang Yijun, Zhang Xiaowei, Yin Wei, Liu Qinghua, Zhang Bing, Su Xingwen, Yu Jun, Hu Songnian, Yan Guangmei   +10 more
doaj   +1 more source

Quantification of snake venom proteomes by mass spectrometry‐considerations and perspectives

Mass Spectrometry Reviews, Volume 43, Issue 5, Page 977-997, September/October 2024.
Abstract The advent of soft ionization mass spectrometry‐based proteomics in the 1990s led to the development of a new dimension in biology that conceptually allows for the integral analysis of whole proteomes. This transition from a reductionist to a global‐integrative approach is conditioned to the capability of proteomic platforms to generate and ...
Juan J. Calvete, Bruno Lomonte, Anthony J. Saviola, Francisco Calderón Celis, Jorge Ruiz Encinar   +4 more
wiley   +1 more source

Toxines et Transferts ioniques [PDF]

, 2011
Collection Rencontres en Toxinologie, ISSN 1760-6004 ; http://sfet.asso.fr/international/images/stories/SFET/pdf/Ebook-RT19-2011-signets.pdfInternational ...
Barbier, Julien, Benoit, Evelyne, Gilles, Nicolas, Ladant, Daniel, Martin-Eauclaire, Marie-France, Mattei, César, Molgó, Jordi, Popoff, Michel R., Servent, Denis   +8 more
core  

Atroxlysin-III, A Metalloproteinase from the Venom of the Peruvian Pit Viper Snake Bothrops atrox (Jergón) Induces Glycoprotein VI Shedding and Impairs Platelet Function

Molecules, 2019
Atroxlysin-III (Atr-III) was purified from the venom of Bothrops atrox. This 56-kDa protein bears N-linked glycoconjugates and is a P-III hemorrhagic metalloproteinase.
L. Oliveira, M. Estevão-Costa, V. Alvarenga, D. Vivas-Ruiz, A. Yarlequé, A. M. Lima, A. Cavaco, J. Eble, E. Sanchez   +8 more
semanticscholar   +1 more source