HeliyonSnake envenomation poses a significant risk to Malaysians and country visitors. Malaysia witnesses an estimated 650 snake bites per 100,000 population annually.
Preetha Rajendiran +3 more
doaj +1 more source
The emerging field of venom-microbiomics for exploring venom as a microenvironment, and the corresponding Initiative for Venom Associated Microbes and Parasites (iVAMP) [PDF]
, 2019 Venom is a known source of novel antimicrobial natural products. The substantial, increasing number of these discoveries have unintentionally culminated in the misconception that venom and venom-producing glands are largely sterile environments.
Adams, Rachelle M.M. +13 more
core +1 more source
KEGG orthology-based annotation of the predicted proteome of Acropora digitifera: ZoophyteBase - an open access and searchable database of a coral genome [PDF]
, 2013 BACKGROUND: Contemporary coral reef research has firmly established that a genomic approach is urgently needed to better understand the effects of anthropogenic environmental stress and global climate change on coral holobiont interactions.
Antonio Starcevic +9 more
core +2 more sources
BJ-PI2, A non-hemorrhagic metalloproteinase from Bothrops jararaca snake venom
Biochimica et Biophysica Acta (BBA) - General Subjects, 2012 Envenoming by Bothrops jararaca can result in local pain, edema, hemorrhage and necrosis, partially mediated by snake venom metalloproteinases (SVMPs). Here, we describe the characterization of BJ-PI2, a P-I class SVMP from B. jararaca venom, and its local tissue actions.BJ-PI2 was purified by a combination of gel filtration, anion-exchange ...
da Silva, Igor Rapp Ferreira +6 more
openaire +2 more sources
Key events in microvascular damage induced by snake venom hemorrhagic metalloproteinases
Journal of Proteomics, 2011 Hemorrhage is one of the most significant effects in envenomings induced by viperid snakebites. Damage to the microvasculature, induced by snake venom metalloproteinases (SVMPs), is the main event responsible for this effect. The precise mechanism by which SVMPs disrupt the microvasculature has remained elusive, although recent developments provide ...
Escalante Muñoz, Teresa +3 more
openaire +4 more sources
Animals living in polluted environments are a potential source of anti-tumour 2 molecule(s) [PDF]
, 2017 Despite advances in in therapeutic interventions and supportive care, the morbidity and mortality associated with cancer has remained significant. Thus there is a need for newer and more powerful anti-tumour agents.
Jeyamogan, Shareni +2 more
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Targeting G-Quadruplexes within the ADAM-15 Promoter: A Novel Therapeutic Approach for Breast Cancer [PDF]
, 2015 ADAM-15 is a protein that is up-regulated in many diseases, particularly breast cancer; its over-expression is correlated with more aggressive and invasive phenotypes.
Jenkins, Rachel L.
core +1 more source
Clinical, hematological and coagulative changes consequent to antibody level increase in horses destined to antivenom production [PDF]
, 2013 El objetivo del trabajo consistió en estudiar los efectos clínicos, hemáticos y coagulativos, así como la producción de anticuerpos en tres equinos inmunizados para la producción de suero antiofídico monovalente contra Bothrops alternatus y evaluar los ...
Acosta, Ofelia Cristina +4 more
core +1 more source
bioRxivSnakebite envenoming is a neglected tropical disease that causes substantial mortality and morbidity globally. The puff adder (Bitis arietans) and saw-scaled viper (Echis romani) have cytotoxic venoms that cause permanent injury via tissue-destructive ...
K. Bartlett +3 more
semanticscholar +1 more source
Highlights in toxicology [PDF]
, 2011 Every year our cooperating journal, the Archives of Toxicology, publishes and analyzes its most cited articles. In 2009/2010 the most popular articles focussed on ethanol-induced liver damage, tea polyphenols as anti-carcinogens and concepts of dose ...
Marchan, R.
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