Results 31 to 40 of about 23,708 (288)

Children and Snakebite: Snake Venom Effects on Adult and Paediatric Plasma

Toxins, 2023
Snakebite is a globally neglected tropical disease, with coagulation disturbances being the primary pathology of many deadly snake venoms. Age-related differences in human plasma have been abundantly reported, yet the effect that these differences pose ...
C. Zdenek, C. F. B. Rodrigues, L. Bourke, A. Tanaka-Azevedo, P. Monagle, B. Fry   +5 more
semanticscholar   +1 more source

Repurposed drugs and their combinations prevent morbidity-inducing dermonecrosis caused by diverse cytotoxic snake venoms

Nature Communications, 2023
Morbidity from snakebite envenoming affects approximately 400,000 people annually. Tissue damage at the bite-site often leaves victims with catastrophic life-long injuries and is largely untreatable by current antivenoms.
Steven R. Hall, Sean A. Rasmussen, Edouard Crittenden, Charlotte A. Dawson, Keirah E. Bartlett, Adam P. Westhorpe, Laura-Oana Albulescu, Jeroen Kool, José María Gutiérrez, Nicholas R. Casewell   +9 more
doaj   +1 more source

National snakebite project on capacity building of health system on prevention and management of snakebite envenoming including its complications in selected districts of Maharashtra and Odisha in India: A study protocol

PLoS ONE, 2023
Background Snakebite envenoming (SBE) is an acute, life-threatening emergency in tropical and subtropical countries. It is an occupational hazard and a major socioeconomic determinant.
R. Gajbhiye, I. K. Chaaithanya, Hrishikesh Munshi, R. Prusty, A. Mahapatra, S. K. Palo, S. Pati, Arun Yadav, Manohar Bansode, Shashikant Shambharkar, Kanna Madavi, H. Bawaskar, S. Mahale   +12 more
semanticscholar   +1 more source

A long-term observational study of paediatric snakebite in Kilifi County, south-east Kenya

PLoS Neglected Tropical Diseases, 2023
Introduction Estimates suggest that one-third of snakebite cases in sub-Saharan Africa affect children. Despite children being at a greater risk of disability and death, there are limited published data.
Michael Abouyannis, M. Boga, D. Amadi, N. Ouma, A. Nyaguara, N. Mturi, J. Berkley, I. Adetifa, N. Casewell, D. Lalloo, M. Hamaluba   +10 more
semanticscholar   +1 more source

Early online

South African Medical Journal, 2023
This article explores the management of snakebite to vulnerable patient groups, namely children and pregnant women as well as providing detail on the current best practice when caring for venom ophthalmia and surgical wounds resulting from snakebite ...
T Hardcastle, A Engelbrecht, V Lalloo, C Bell, M Toubkin, F Motara, M Kajee   +6 more
doaj   +1 more source

Varespladib in the Treatment of Snakebite Envenoming: Development History and Preclinical Evidence Supporting Advancement to Clinical Trials in Patients Bitten by Venomous Snakes

Toxins, 2022
The availability of effective, reliably accessible, and affordable treatments for snakebite envenoming is a critical and long unmet medical need. Recently, small, synthetic toxin-specific inhibitors with oral bioavailability used in conjunction with ...
M. Lewin, R. Carter, Isabel A. Matteo, S. Samuel, Sunita Rao, B. Fry, P. Bickler   +6 more
semanticscholar   +1 more source

Machine-learning guided Venom Induced Dermonecrosis Analysis tooL: VIDAL

Scientific Reports, 2023
Snakebite envenoming is a global public health issue that causes significant morbidity and mortality, particularly in low-income regions of the world.
William Laprade, Keirah E. Bartlett, Charlotte R. Christensen, Taline D. Kazandjian, Rohit N. Patel, Edouard Crittenden, Charlotte A. Dawson, Marjan Mansourvar, Darian S. Wolff, Thomas Fryer, Andreas H. Laustsen, Nicholas R. Casewell, José María Gutiérrez, Steven R. Hall, Timothy P. Jenkins   +14 more
doaj   +1 more source

Barriers to the hospital treatment among Bede snake charmers in Bangladesh with special reference to venomous snakebite.

PLoS Neglected Tropical Diseases, 2023
Snakebite envenoming is a potentially life-threatening global public health issue with Bangladesh having one of the highest rates of snakebite cases. The Bede, a nomadic ethnic group in Bangladesh, traditionally engages in snake-related business such as ...
Ken Yoshimura, Moazzem Hossain, Bumpei Tojo, Paul Tieu, Nathalie Nguyen Trinh, Nguyen Tien Huy, Miho Sato, Kazuhiko Moji   +7 more
doaj   +1 more source

Snakebite: An Exploratory Cost-Effectiveness Analysis of Adjunct Treatment Strategies. [PDF]

, 2018
The cost-effectiveness of the standard of care for snakebite treatment, antivenom, and supportive care has been established in various settings. In this study, based on data from South Indian private health-care providers, we address an additional ...
Bulfone, Tommaso C, Herzel, Benjamin J, Kahn, James G, Lewin, Matthew, Raj, C Soundara, Samuel, Stephen P   +5 more
core   +2 more sources

Snakebite envenoming in Brazilian children: clinical aspects, management and outcomes.

Journal of Tropical Pediatrics, 2023
Snakebite envenoming is currently considered a neglected tropical disease, which affects over 5 million people worldwide, and causes almost 150 000 deaths every year, as well as severe injuries, amputations and other sequelae.
I. Oliveira, Manuela B. Pucca, F. Cerni, Samuel Vieira, Jacqueline A G Sachett, Altair Seabra de Farias, M. Lacerda, F. Murta, D. Baía-da-Silva, T. Rocha, L. Silva, Q. Bassat, J. Vissoci, C. Gerardo, V. Sampaio, F. H. Wen, P. Bernarde, W. Monteiro   +17 more
semanticscholar   +1 more source