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Fusion Machinery: SNARE Protein Complex
2014SNARE proteins constitute the minimal machinery needed for membrane fusion. SNAREs operate by forming a complex, which pulls the lipid bilayers into close contact and provides the mechanical force needed for lipid bilayer fusion. At the chemical synapse, SNARE-complex formation between the vesicular SNARE VAMP2/synaptobrevin-2 and the target (plasma ...
Sørensen, Jakob Balslev, Milosevic, Ira
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Volatile Anesthetics Bind Rat Synaptic Snare Proteins
Anesthesiology, 2005Background Volatile general anesthetics (VAs) have a number of synaptic actions, one of which is to inhibit excitatory neurotransmitter release; however, no presynaptic VA binding proteins have been identified. Genetic data in Caenorhabditis elegans have led to the hypothesis that a protein that interacts with the presynaptic ...
Peter, Nagele +5 more
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Mechanisms of SNARE proteins in membrane fusion
Nature Reviews Molecular Cell Biology, 2023Reinhard Jahn, Lukas K Tamm
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DIRECT INTERACTION IN ARABIDOPSIS OF SNARE PROTEIN SYP51 WITH NON-SNARE PROTEIN NLM1
2014SNAREs (N-ethylmaleimide-sensitive factor adaptor protein receptors) are small polypeptides characterized by a particular domain, the SNARE motif, that can form a coiled-coil structure. Via hetero-oligomeric interactions, these proteins form highly stable protein-protein interactions, the so called SNARE-complex, that allow membrane fusion. SNAREs also
DI SANSEBASTIANO, Gian Pietro +2 more
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Chaperoning SNARE Folding and Assembly
Annual Review of Biochemistry, 2021Yongli Zhang, Frederick M Hughson
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Chaperoning SNARE assembly and disassembly
Nature Reviews Molecular Cell Biology, 2016Frederick M Hughson
exaly