Snf7 spirals sense and alter membrane curvature [PDF]
Nature Communications, 2022 Snf7 is the major component of the ESCRTIII membrane deformation system. Here, the authors used high-speed AFM to study Snf7 on nano-patterned and soft supports and show that loaded Snf7 spiral springs are curvature sensitive and deform membranes.
Nebojsa Jukic +2 more
exaly +6 more sources
ESCRT-III subunits Snf7-1 and Snf7-2 differentially regulate transmembrane cargos in hESC-derived human neurons [PDF]
Molecular Brain, 2011 Backgrounds Endosomal sorting complex required for transport (ESCRT) is involved in several fundamental cellular processes and human diseases. Many mammalian ESCRT proteins have multiple isoforms but their precise functions remain largely unknown ...
Jin-A Lee, Céline Delaloy, Fen-Biao Gao
exaly +13 more sources
Vtc4 Promotes the Entry of Phagophores into Vacuoles in the Saccharomyces cerevisiae Snf7 Mutant Cell [PDF]
Journal of Fungi, 2023 Endocytosis and autophagy are the main pathways to deliver cargoes in vesicles and autophagosomes, respectively, to vacuoles/lysosomes in eukaryotes. Multiple positive regulators but few negative ones are reported to regulate the entry of vesicles and ...
Xiaofan Chen, Yongheng Liang
doaj +4 more sources
Physiological and Cellular Responses Caused by RNAi- Mediated Suppression of Snf7 Orthologue in Western Corn Rootworm (Diabrotica virgifera virgifera) Larvae [PDF]
PLoS ONE, 2013 Ingestion of double stranded RNA (dsRNA) has been previously demonstrated to be effective in triggering RNA interference (RNAi) in western corn rootworm (WCR, Diabrotica virgifera virgifera LeConte), providing potential novel opportunities for insect ...
Brian Mcnulty
exaly +5 more sources
Crucial role of Snf7-3 in synaptic function and cognitive behavior revealed by conventional and conditional knockout mouse models [PDF]
NeuroscienceSnf7-3 is a crucial component of the endosomal sorting complexes required for transport (ESCRT) pathway, playing a vital role in endolysosomal functions. To elucidate the role of Snf7-3 in vivo, we developed conventional-like and conditional Snf7-3 knockout (KO) mouse models using a "Knockout-first" strategy.
Jin-A Lee, Bong-Kiun Kaang, Su-Eon Sim
exaly +4 more sources
The chromosomal passenger complex controls the function of endosomal sorting complex required for transport-III Snf7 proteins during cytokinesis [PDF]
Open Biology, 2012 Summary Cytokinesis controls the proper segregation of nuclear and cytoplasmic materials at the end of cell division. The chromosomal passenger complex (CPC) has been proposed to monitor the final separation of the two daughter cells at the end of ...
Luisa Capalbo +5 more
doaj +6 more sources
Electrospinning of core shell nanofibers using amine modified sericins [PDF]
Scientific ReportsIn this study as a renewable resorce, silk sericin (SS), a protein surrounding fibroin fibers in silk, was chemically modified with various amines (e.g., methylamine, butylamine) to improve its functional properties.
Demet Sezgin Mansuroglu +3 more
doaj +2 more sources
Optimal dsRNA Concentration for RNA Interference in Asian Citrus Psyllid [PDF]
InsectsThe Asian citrus psyllid (ACP) is a citrus pest and insect vector of “Candidatus Liberibacter asiaticus”, the causal agent of citrus greening disease. Double-stranded RNA (dsRNA) biopesticides that trigger RNA interference (RNAi) offer an alternative to ...
Esmaeil Saberi +5 more
doaj +2 more sources
The phage shock protein (PSP) envelope stress response: discovery of novel partners and evolutionary history [PDF]
mSystemsBacterial phage shock protein (PSP) systems stabilize the bacterial cell membrane and protect against envelope stress. These systems have been associated with virulence, but despite their critical roles, PSP components are not well characterized outside ...
Janani Ravi +6 more
doaj +2 more sources
Design principles of the ESCRT-III Vps24-Vps2 module
eLife, 2021 ESCRT-III polymerization is required for all endosomal sorting complex required for transport (ESCRT)-dependent events in the cell. However, the relative contributions of the eight ESCRT-III subunits differ between each process.
Sudeep Banjade +3 more
doaj +1 more source