Mutational Analysis of Candida albicans SNF7 Reveals Genetically Separable Rim101 and ESCRT Functions and Demonstrates Divergence in bro1-Domain Protein Interactions [PDF]
Abstract The opportunistic pathogen Candida albicans can grow over a wide pH range, which is associated with its ability to colonize and infect distinct host niches. C. albicans growth in neutral-alkaline environments requires proteolytic activation of the transcription factor Rim101.
Dana A Davis
exaly +4 more sources
The evolutionary conserved ESCRT-III complex is a device for membrane remodelling in various cellular processes, such as the formation of intraluminal vesicles (ILVs), cytokinesis, and membrane repair.
Miriam Baeumers, K. Schulz, T. Klein
semanticscholar +3 more sources
Identification of Yeast Protein Sequences With Similarity to the ESCRT-III Protein Snf7.
ABSTRACT Endosomal sorting complex required for transport (ESCRT‐III) is a membrane remodeling complex involved in a large number of cellular processes. It appears to perform an essential function in eukaryotes, since to date no eukaryotic organism completely devoid of ESCRT‐III has been found.
T. Brune, R. Kölling
semanticscholar +2 more sources
Electrospinning of core shell nanofibers using amine modified sericins [PDF]
In this study as a renewable resorce, silk sericin (SS), a protein surrounding fibroin fibers in silk, was chemically modified with various amines (e.g., methylamine, butylamine) to improve its functional properties.
Demet Sezgin Mansuroglu +3 more
doaj +2 more sources
Autophagosome closure by ESCRT: Vps21/RAB5-regulated ESCRT recruitment via an Atg17-Snf7 interaction [PDF]
The macroautophagy/autophagy pathway includes successive steps of phagophore assembly structure formation, phagophore expansion, autophagosome (AP) closure and AP fusion with the lysosome/vacuole.
Fan Zhou +4 more
semanticscholar +3 more sources
Membrane binding of a cyanobacterial ESCRT-III protein crucially involves the helix α1-3 hairpin conserved in all superfamily members. [PDF]
Abstract IM30, the inner membrane‐associated protein of 30 kDa (also known as Vipp1) is essential for thylakoid membrane biogenesis and/or maintenance in chloroplasts and cyanobacteria. IM30 and its bacterial homolog PspA belong to the ESCRT‐III superfamily, proteins previously thought to be restricted to eukaryotes and archaea.
Schlösser L +16 more
europepmc +3 more sources
Vacuolar transport and function of Saccharomyces cerevisiae sterol ester hydrolase Tgl1. [PDF]
Tgl1, one of yeast sterol ester hydrolases, had been found on the lipid droplets where sterol esters are mainly stored. This study revealed that Tgl1 is transported into the vacuole depending on the ESCRT‐I–III complex, and that it exhibits intra‐vacuolar sterol ester hydrolase activity.
Nakatsuji T +5 more
europepmc +2 more sources
Optimal dsRNA Concentration for RNA Interference in Asian Citrus Psyllid [PDF]
The Asian citrus psyllid (ACP) is a citrus pest and insect vector of “Candidatus Liberibacter asiaticus”, the causal agent of citrus greening disease. Double-stranded RNA (dsRNA) biopesticides that trigger RNA interference (RNAi) offer an alternative to ...
Esmaeil Saberi +5 more
doaj +2 more sources
ESCRT-III Protein Snf7 Mediates High-Level Expression of the SUC2 Gene via the Rim101 Pathway
The yeast (Saccharomyces cerevisiae) Snf7 family consists of six highly charged, coiled-coil-forming proteins involved in multivesicular body (MVB) formation. Although all proteins perform a common function at late endosomes, individual mutants also show
Ralf Koelling
exaly +2 more sources
Plasma membrane damage limits replicative lifespan in yeast and induces premature senescence in human fibroblasts. [PDF]
Plasma membrane damage (PMD) occurs in all cell types due to environmental perturbation and cell-autonomous activities. However, cellular outcomes of PMD remain largely unknown except for recovery or death.
Suda K +14 more
europepmc +2 more sources

