Results 91 to 100 of about 2,258 (157)

Aspergillus nidulans ambient pH signaling does not require endocytosis

, 2015
9 p.-6 fig.-1 tab.Aspergillus nidulans (Pal) ambient pH signaling takes place in cortical structures containing components of the ESCRT pathway, which are hijacked by the alkaline pH-activated, ubiquitin-modified version of the arrestin-like protein PalF
Arst, HN, Galindo, A, Lucena-Agell, D, Penalva, MA   +3 more
core   +1 more source

Activation of the Endosome-Associated Ubiquitin Isopeptidase AMSH by STAM, a Component of the Multivesicular Body-Sorting Machinery [PDF]

, 2006
AMSH is an endosomal ubiquitin isopeptidase that can limit EGF receptor downregulation [1]. It directly binds to the SH3 domain of STAM, which is constitutively associated with Hrs, a component of clathrin-coated structures on endosomes.
Paula Row
core   +1 more source

Otilonium Bromide Exhibits Potent Antifungal Effects by Blocking Ergosterol Plasma Membrane Localization and Triggering Cytotoxic Autophagy in Candida Albicans

Advanced Science, Volume 11, Issue 35, September 18, 2024.
Otilonium bromide (OTB) demonstrates efficacy against Candida albicans by targeting Sec31, thereby impeding vesicle transport and ergosterol localization, ultimately inducing cytotoxic autophagy. C. albicans exhibits susceptibility to OTB because it does not act as a substrate of drug pumps.
Cheng Zhen, Li Wang, Yanru Feng, Malcolm Whiteway, Sijin Hang, Jinhua Yu, Hui Lu, Yuanying Jiang   +7 more
wiley   +1 more source

CHMP4B contributes to maintaining the follicular cells integrity in the panoistic ovary of the cockroach Blattella germanica

Biology of the Cell, Volume 116, Issue 9, September 2024.
In the panoistic ovary of the cockroach Blattella germanica, CHMP4B, a component of the ESCRT‐III subcomplex, is crucial in regulating the cytoskeleton protein expression to preserve the basal ovarian follicle growth and maturation. Depletion of Chmp4b through RNA interference results in an increase in actin expression in the ovary.
Nuria Farrus, José Luis Maestro, Maria‐Dolors Piulachs   +2 more
wiley   +1 more source

Suppressor of K+ transport growth defect 1 (SKD1) interactswith RING-type ubiquitin ligase and sucrose non-fermenting1-related protein kinase (SnRK1) in the halophyte ice plant [PDF]

, 2013
SKD1 (suppressor of K+ transport growth defect 1) is an AAA-type ATPase that functions as a molecular motor. It was previously shown that SKD1 accumulates in epidermal bladder cells of the halophyte Mesembryanthemum crystallinum.
Chang-Hua Li, Chih-Pin Chiang, Fang-Yu Yang, Hungchen Emilie Yen, Nu-Chuan Huang, Ya-Chung Lin, Yingtzy Jou, Yu-Chan Chen   +7 more
core   +1 more source

Row1, a member of a new family of conserved fungal proteins involved in infection, is required for appressoria functionality in Ustilago maydis

New Phytologist, Volume 243, Issue 3, Page 1101-1122, August 2024.
Summary The appressorium of phytopathogenic fungi is a specific structure with a crucial role in plant cuticle penetration. Pathogens with melanized appressoria break the cuticle through cell wall melanization and intracellular turgor pressure. However, in fungi with nonmelanized appressorium, the mechanisms governing cuticle penetration are poorly ...
María Dolores Pejenaute‐Ochoa, Laura Tomás‐Gallardo, José I. Ibeas, Ramón R. Barrales   +3 more
wiley   +1 more source

Degenerate Tetraploidy Was Established Before Bdelloid Rotifer Families Diverged [PDF]

, 2008
Rotifers of Class Bdelloidea are abundant freshwater invertebrates known for their remarkable ability to survive desiccation and their lack of males and meiosis.
Hur, Jae H., Mandigo, Morgan L., Meselson, Matthew, Van Doninck, Karine   +3 more
core   +2 more sources

Assessment of genetically modified maize MON 95275 (application GMFF‐2022‐5890)

EFSA Journal, Volume 22, Issue 8, August 2024.
Abstract Genetically modified maize MON 95275 was developed to confer protection to certain coleopteran species. These properties were achieved by introducing the mpp75Aa1.1, vpb4Da2 and DvSnf7 expression cassettes. The molecular characterisation data and bioinformatic analyses reveal similarity to known toxins, which was further assessed.
EFSA Panel on Genetically Modified Organisms (GMO), Ewen Mullins, Jean‐Louis Bresson, Tamas Dalmay, Ian Crawford Dewhurst, Michelle M. Epstein, Leslie George Firbank, Philippe Guerche, Jan Hejatko, Hanspeter Naegeli, Francisco Javier Moreno, Fabien Nogué, Nils Rostoks, Jose Juan Sánchez Serrano, Giovanni Savoini, Eve Veromann, Fabio Veronesi, Michele Ardizzone, Giacomo De Sanctis, Federici Silvia, Antonio Fernandez Dumont, Andrea Gennaro, José Ángel Gómez Ruiz, Paschalina Grammatikou, Tilemachos Goumperis, Dafni Maria Kagkli, Paolo Lenzi, Aleksandra Lewandowska, Ana Martin Camargo, Franco Maria Neri, Pietro Piffanelli, Tommaso Raffaello, Kyriaki Xiftou   +32 more
wiley   +1 more source

Mitochondria Autophagy in Yeast [PDF]

, 2011
The mitochondrion is an organelle that carries out a number of important metabolic processes such as fatty acid oxidation, the citric acid cycle, and oxidative phosphorylation.
Kanki, Tomotake, Klionsky, Daniel J., Okamoto, Koji   +2 more
core   +2 more sources

Characterisation of extracellular vesicles in baculovirus infection of Spodoptera frugiperda cells

Journal of Extracellular Biology, Volume 3, Issue 7, July 2024.
Abstract Autographa californica multiple nucleopolyhedrovirus (AcMNPV) is an enveloped DNA virus of the Baculoviridae family. This baculovirus is widely exploited for the biological control of insect pest species and as an expression platform to produce recombinant proteins in insect cells. Extracellular vesicles (EVs) are secreted by all cells and are
Lex J. C. Van Es, Robert D. Possee, Linda A. King   +2 more
wiley   +1 more source