In the panoistic ovary of the cockroach Blattella germanica, CHMP4B, a component of the ESCRT‐III subcomplex, is crucial in regulating the cytoskeleton protein expression to preserve the basal ovarian follicle growth and maturation. Depletion of Chmp4b through RNA interference results in an increase in actin expression in the ovary.
Nuria Farrus +2 more
wiley +1 more source
Wrapping up the bad news: HIV assembly and release. [PDF]
The late Nobel Laureate Sir Peter Medawar once memorably described viruses as 'bad news wrapped in protein'. Virus assembly in HIV is a remarkably well coordinated process in which the virus achieves extracellular budding using primarily intracellular ...
Lever, Andrew Ml, Meng, Bo
core +3 more sources
Summary The appressorium of phytopathogenic fungi is a specific structure with a crucial role in plant cuticle penetration. Pathogens with melanized appressoria break the cuticle through cell wall melanization and intracellular turgor pressure. However, in fungi with nonmelanized appressorium, the mechanisms governing cuticle penetration are poorly ...
María Dolores Pejenaute‐Ochoa +3 more
wiley +1 more source
Activation of the Endosome-Associated Ubiquitin Isopeptidase AMSH by STAM, a Component of the Multivesicular Body-Sorting Machinery [PDF]
AMSH is an endosomal ubiquitin isopeptidase that can limit EGF receptor downregulation [1]. It directly binds to the SH3 domain of STAM, which is constitutively associated with Hrs, a component of clathrin-coated structures on endosomes.
Paula Row
core +1 more source
Chromatin Accessibility-Based Characterization of the Gene Regulatory Network Underlying Plasmodium falciparum Blood-Stage Development. [PDF]
Underlying the development of malaria parasites within erythrocytes and the resulting pathogenicity is a hardwired program that secures proper timing of gene transcription and production of functionally relevant proteins.
Bártfai, R +5 more
core +1 more source
Suppressor of K+ transport growth defect 1 (SKD1) interactswith RING-type ubiquitin ligase and sucrose non-fermenting1-related protein kinase (SnRK1) in the halophyte ice plant [PDF]
SKD1 (suppressor of K+ transport growth defect 1) is an AAA-type ATPase that functions as a molecular motor. It was previously shown that SKD1 accumulates in epidermal bladder cells of the halophyte Mesembryanthemum crystallinum.
Chang-Hua Li +7 more
core +1 more source
Ubiquitin-Mediated Degradation of Aurora Kinases. [PDF]
The Aurora kinases are essential regulators of mitosis in eukaryotes. In somatic cell divisions of higher eukaryotes, the paralogs Aurora kinase A (AurA) and Aurora kinase B (AurB) play non-overlapping roles that depend on their distinct spatiotemporal ...
Grant, Rhys +2 more
core +2 more sources
Degenerate Tetraploidy Was Established Before Bdelloid Rotifer Families Diverged [PDF]
Rotifers of Class Bdelloidea are abundant freshwater invertebrates known for their remarkable ability to survive desiccation and their lack of males and meiosis.
Hur, Jae H. +3 more
core +2 more sources
Analysis of sphingolipid-signaling at the plasma membrane of Saccharomyces cerevisiae [PDF]
The protein and lipid composition of eukaryotic plasma membranes is highly dynamic and regulated according to need. Despite its great plasticity, the plasma membrane retains some organizational features, such as its lateral organization into distinct ...
Fröhlich, Florian
core
Nature's lessons in design: nanomachines to scaffold, remodel and shape membrane compartments. [PDF]
Compartmentalisation of cellular processes is fundamental to regulation of metabolism in Eukaryotic organisms and is primarily provided by membrane-bound organelles.
Achalkumar +198 more
core +2 more sources

