Increased RNAi efficacy in Spodoptera exigua via the formulation of dsRNA with guanylated polymers [PDF]
Lepidoptera comprise some of the most devastating herbivorous pest insects worldwide. One of the most promising novel pest control strategies is exploiting the RNA interference (RNAi) mechanism to target essential genes for knockdown and incite toxic ...
Christiaens, Olivier +5 more
core +3 more sources
Engineering Yeast Extracellular Vesicle Biogenesis Through Rewiring Membrane Trafficking Pathways
Engineered Saccharomyces cerevisiae reveals how cell wall remodelling and membrane trafficking coordinate extracellular vesicle biogenesis. Interferon overexpression and chs3 deletion enhance EV secretion and reshape SNARE‐, Rab‐ and ESCRT‐associated pathways, establishing yeast as a versatile platform for EV engineering and therapeutic cargo loading ...
Yueyan Li +11 more
wiley +1 more source
Interacting boson fermion-fermion model calculation of the h11/2h11/2 doublet bands in 134Pr [PDF]
The interacting boson fermion-fermion model is employed in the analysis of the positive-parity doublet bands in 134Pr. It is shown that stable triaxial deformation gives rise to the experimentally observed crossing between the yrast and yrare bands built
Brant, Slobodan +2 more
core +3 more sources
Southern Corn Rootworm (Coleoptera: Chrysomelidae) Adult Emergence and Population Growth Assessment After Selection With Vacuolar ATPase-A double-stranded RNA Over Multiple Generations [PDF]
The southern corn rootworm, Diabrotica undecimpunctata howardi Barber (Coleoptera: Chrysomelidae), was exposed over multiple generations to vacuolar (v)ATPase-A double-stranded (ds)RNA, first as adults and later, as neonate larvae. During adult selection,
Meinke, Lance J. +3 more
core +1 more source
Phagocytic cells capture and kill most invader microbes within the bactericidal phagosome, but some pathogens subvert killing by damaging the compartment and escaping to the cytosol.
Ana T López-Jiménez +7 more
doaj +1 more source
Frontotemporal Dementia Linked to Chromosome 3 in Saccharomyces cerevisiae [PDF]
Frontotemporal dementia (FTD) represents a crippling new neurodegenerative disease for scientific investigation. Marked by characteristic frontal and temporal lobar cortical atrophy, FTD results in the progressive deterioration of social and behavioral ...
Sulkko, Niles
core +2 more sources
High-resolution genome-wide scan of genes, gene-networks and cellular systems impacting the yeast ionome [PDF]
Peer reviewedPublisher ...
Baxter, Ivan +7 more
core +2 more sources
On the microstructure of active cellular processes [PDF]
Eukaryotic cells use a multitude of protein machines to regulate their own structure. In this thesis, we study how the geometrical arrangement of these interacting microscopic active elements sculpt the cell's own internal microstructure and its membrane
Lenz, Martin
core +2 more sources
Structural Basis for Regulation of ESCRT-III Complexes by Lgd
The ESCRT-III complex induces outward membrane budding and fission through homotypic polymerization of its core component Shrub/CHMP4B. Shrub activity is regulated by its direct interaction with a protein called Lgd in flies, or CC2D1A or B in humans ...
Brian J. McMillan +5 more
doaj +1 more source
Stage-specific proteomes from onchocerca ochengi, sister species of the human river blindness parasite, uncover adaptations to a nodular lifestyle [PDF]
Despite 40 years of control efforts, onchocerciasis (river blindness) remains one of the most important neglected tropical diseases, with 17 million people affected.
Adam +155 more
core +6 more sources

