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Multiple testing for SNP-SNP interactions [PDF]
Statistical Applications in Genetics and Molecular Biology, 2007 Most genetic diseases are complex, i.e. associated to combinations of SNPs rather than individual SNPs. In the last few years, this topic has often been addressed in terms of SNP-SNP interaction patterns given as expressions linked by logical operators ...
Boulesteix, Anne-Laure +4 more
core +6 more sources
Time After Time: Notes on Delays In Spiking Neural P Systems [PDF]
arXiv, 2012 Spiking Neural P systems, SNP systems for short, are biologically inspired computing devices based on how neurons perform computations. SNP systems use only one type of symbol, the spike, in the computations. Information is encoded in the time differences of spikes or the multiplicity of spikes produced at certain times.
A. Alhazov +7 more
arxiv +3 more sources
A Remark on the Second Neighborhood Problem [PDF]
Electronic Journal of Graph Theory and Applications 3(1): 182-190
(2015), 2015 Seymour's second neighborhood conjecture states that every simple digraph (without digons) has a vertex whose first out-neighborhood is at most as large as its second out-neighborhood. Such a vertex is said to have the second neighborhood property (SNP). We define "good" digraphs and prove a statement that implies that every feed vertex of a tournament
Ghazal, Salman
arxiv +5 more sources
Integrated probability of coronary heart disease subject to the -308 tumor necrosis factor-alpha SNP: a Bayesian meta-analysis [PDF]
, 2015 We present a meta-analysis of independent studies on the potential implication in the occurrence of coronary heart disease (CHD) of the single-nucleotide polymorphism (SNP) at the -308 position of the tumor necrosis factor alpha (TNF-alpha) gene. We use Bayesian analysis to integrate independent data sets and to infer statistically robust measurements ...
Carvalho, C. Sofia
arxiv +5 more sources
Clinical Significance and Management of Hyponatremia in Liver Cirrhosis
Gastroenterology Insights, 2023 The overall prevalence of hyponatremia in cirrhotics is around 50%. Hypovolemic hyponatremia is a result of excessive fluid loss caused mostly by diuretic treatment or diarrhea.
Martin Janičko +6 more
doaj +1 more source
Selected In Situ Hybridization Methods: Principles and Application
Molecules, 2021 We are experiencing rapid progress in all types of imaging techniques used in the detection of various numbers and types of mutation. In situ hybridization (ISH) is the primary technique for the discovery of mutation agents, which are presented in a ...
Dominika Veselinyová +5 more
doaj +1 more source
SNP-VISTA: An interactive SNP visualization tool [PDF]
BMC Bioinformatics, 2005 Abstract Background Recent advances in sequencing technologies promise to provide a better understanding of the genetics of human disease as well as the evolution of microbial populations. Single Nucleotide Polymorphisms (SNPs) are established genetic markers that aid in the identification of loci affecting quantitative ...
Inna Dubchak +10 more
openaire +5 more sources
SNP-Flankplus: SNP ID-centric retrieval for SNP flanking sequences [PDF]
Bioinformation, 2008 The flanking sequences provided by dbSNP of NCBI are usually short and fixed length without further extension, thus making the design of appropriate PCR primers difficult. Here, we introduce a tool named "SNP-Flankplus" to provide a web environment for retrieval of SNP flanking sequences from both the dbSNP and the nucleotide databases of NCBI. Two SNP
Li-Yeh Chuang +3 more
openaire +3 more sources
SNP by SNP by environment interaction network of alcoholism [PDF]
BMC Systems Biology, 2017 Alcoholism has a strong genetic component. Twin studies have demonstrated the heritability of a large proportion of phenotypic variance of alcoholism ranging from 50-80%. The search for genetic variants associated with this complex behavior has epitomized sequence-based studies for nearly a decade. The limited success of genome-wide association studies
Gil Alterovitz +3 more
openaire +3 more sources