PTPN2 gene variants are associated with susceptibility to both Crohn's disease and ulcerative colitis supporting a common genetic disease background. [PDF]
, 2012 Genome-wide association studies identified PTPN2 (protein tyrosine phosphatase, non-receptor type 2) as susceptibility gene for inflammatory bowel diseases (IBD).
Beigel, Florian +15 more
core +13 more sources
Clinical Significance and Management of Hyponatremia in Liver Cirrhosis
Gastroenterology Insights, 2023 The overall prevalence of hyponatremia in cirrhotics is around 50%. Hypovolemic hyponatremia is a result of excessive fluid loss caused mostly by diuretic treatment or diarrhea.
Martin Janičko +6 more
doaj +1 more source
Selected In Situ Hybridization Methods: Principles and Application
Molecules, 2021 We are experiencing rapid progress in all types of imaging techniques used in the detection of various numbers and types of mutation. In situ hybridization (ISH) is the primary technique for the discovery of mutation agents, which are presented in a ...
Dominika Veselinyová +5 more
doaj +1 more source
Biomedicines, 2023 Purpose: The development of sensitive and non-invasive biomarkers for the early detection of CRC and determination of their role in the individual stages of CRC.
Ivana Večurkovská +7 more
doaj +1 more source
Life, 2023 Osteoarthritis (OA) is the most common degenerative disease of the connective tissue of the human musculoskeletal system. Despite its widespread prevalence, there are many limitations in its diagnosis and treatment.
Marko Moravek +2 more
doaj +1 more source
GBS-SNP-CROP: a reference-optional pipeline for SNP discovery and plant germplasm characterization using variable length, paired-end genotyping-by-sequencing data [PDF]
, 2016 Background: With its simple library preparation and robust approach to genome reduction, genotyping-by-sequencing (GBS) is a flexible and cost-effective strategy for SNP discovery and genotyping, provided an appropriate reference genome is available. For
Bartaula, Radhika +2 more
core +2 more sources
Serum cholesterol is a significant and independent mortality predictor in liver cirrhosis patients
Annals of Hepatology, 2013 Background and Aim. Accurate assessment of cirrhotic patient’s prognosis is essential for decisions regarding the course of treatment. Therefore we aimed to confirm and quantify the predictive value of serum cholesterol and serum triglycerides in liver ...
Martin Janičko +3 more
doaj +1 more source
Co-Encapsulated Synbiotics and Immobilized Probiotics in Human Health and Gut Microbiota Modulation
Foods, 2021 Growing interest in the development of innovative functional products as ideal carriers for synbiotics, e.g., nutrient bars, yogurt, chocolate, juice, ice cream, and cheese, to ensure the daily intake of probiotics and prebiotics, which are needed to ...
Monika Kvakova +3 more
doaj +1 more source
Probiotic-Based Intervention in the Treatment of Ulcerative Colitis: Conventional and New Approaches
Biomedicines, 2022 Although there are number of available therapies for ulcerative colitis (UC), many patients are unresponsive to these treatments or experience secondary failure during treatment.
Jana Štofilová +5 more
doaj +1 more source
Epidemiological risks of endoparasitoses spread by municipal waste water
Helminthologia, 2015 The occurrence of developmental stages of endoparasite germs (cysts, oocysts, protozoa, and helminth eggs) as an indirect detection factor of endoparasitoses circulation in the environment, was examined in raw municipal wastewater, sludge and ...
Dudlová A. +5 more
doaj +1 more source