Results 1 to 10 of about 293,293 (239)
Multiple Testing for SNP-SNP Interactions [PDF]
Statistical Applications in Genetics and Molecular Biology, 2007 Most genetic diseases are complex, i.e. associated to combinations of SNPs rather than individual SNPs. In the last few years, this topic has often been addressed in terms of SNP-SNP interaction patterns given as expressions linked by logical operators.
Anne-Laure, Boulesteix +4 more
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Clinical Significance and Management of Hyponatremia in Liver Cirrhosis
Gastroenterology Insights, 2023 The overall prevalence of hyponatremia in cirrhotics is around 50%. Hypovolemic hyponatremia is a result of excessive fluid loss caused mostly by diuretic treatment or diarrhea.
Martin Janičko +6 more
doaj +1 more source
SNP-Flankplus: SNP ID-centric retrieval for SNP flanking sequences [PDF]
Bioinformation, 2008 The flanking sequences provided by dbSNP of NCBI are usually short and fixed length without further extension, thus making the design of appropriate PCR primers difficult. Here, we introduce a tool named "SNP-Flankplus" to provide a web environment for retrieval of SNP flanking sequences from both the dbSNP and the nucleotide databases of NCBI. Two SNP
Cheng-Hong, Yang +3 more
openaire +2 more sources
Selected In Situ Hybridization Methods: Principles and Application
Molecules, 2021 We are experiencing rapid progress in all types of imaging techniques used in the detection of various numbers and types of mutation. In situ hybridization (ISH) is the primary technique for the discovery of mutation agents, which are presented in a ...
Dominika Veselinyová +5 more
doaj +1 more source
SNP-VISTA: An interactive SNP visualization tool [PDF]
BMC Bioinformatics, 2005 Abstract Background Recent advances in sequencing technologies promise to provide a better understanding of the genetics of human disease as well as the evolution of microbial populations. Single Nucleotide Polymorphisms (SNPs) are established genetic markers that aid in the identification of loci affecting quantitative ...
Shah, Nameeta +6 more
openaire +5 more sources
SNP-SNP interactions in breast cancer susceptibility [PDF]
BMC Cancer, 2006 AbstractBackgroundBreast cancer predisposition genes identified to date (e.g., BRCA1 and BRCA2) are responsible for less than 5% of all breast cancer cases. Many studies have shown that the cancer risks associated with individual commonly occurring single nucleotide polymorphisms (SNPs) are incremental.
Onay, Venüs Ü +9 more
openaire +4 more sources
Biomedicines, 2023 Purpose: The development of sensitive and non-invasive biomarkers for the early detection of CRC and determination of their role in the individual stages of CRC.
Ivana Večurkovská +7 more
doaj +1 more source
SNP-PHAGE – High throughput SNP discovery pipeline [PDF]
BMC Bioinformatics, 2006 AbstractBackgroundSingle nucleotide polymorphisms (SNPs) as defined here are single base sequence changes or short insertion/deletions between or within individuals of a given species. As a result of their abundance and the availability of high throughput analysis technologies SNP markers have begun to replace other traditional markers such as ...
Matukumalli, Lakshmi K. +5 more
openaire +3 more sources
Life, 2023 Osteoarthritis (OA) is the most common degenerative disease of the connective tissue of the human musculoskeletal system. Despite its widespread prevalence, there are many limitations in its diagnosis and treatment.
Marko Moravek +2 more
doaj +1 more source
Serum cholesterol is a significant and independent mortality predictor in liver cirrhosis patients
Annals of Hepatology, 2013 Background and Aim. Accurate assessment of cirrhotic patient’s prognosis is essential for decisions regarding the course of treatment. Therefore we aimed to confirm and quantify the predictive value of serum cholesterol and serum triglycerides in liver ...
Martin Janičko +3 more
doaj +1 more source