Results 101 to 110 of about 434,626 (308)

Proteomic and bioinformatics analysis of human saliva for the dental-risk assessment

open access: yesOpen Life Sciences, 2017
Background: Dental caries disease is a dynamic process with a multi-factorial etiology. It is manifested by demineralization of enamel followed by damage spreading into the tooth inner structure.
Laputková Galina   +5 more
doaj   +1 more source

Dinâmica das formas de fósforo em solos de textura e mineralogia contrastantes cultivados com arroz - doi: 10.4025/actasciagron.v33i1.1435

open access: yesActa Scientiarum. Agronomy, 2011
O experimento foi conduzido com o objetivo de avaliar a influência da aplicação de silício (Si) e fósforo (P) sobre as formas orgânicas e inorgânicas do P em dois solos (Neossolo Quartzarênico órtico e Latossolo Vermelho distroférrico – LVdf), com ...
Alessandra Mayumi Tokura   +5 more
doaj   +1 more source

Lactiplantibacillus Plantarum GUANKE Alleviates Allergic Asthma by Restricting Monocyte‐to‐DC Differentiation Via Microbiota‐Associated IAA

open access: yesAdvanced Science, EarlyView.
Lactiplantibacillus plantarum GUANKE remodels the indigenous gut microbiota and is associated with microbiota‐dependent restoration of circulating IAA. IAA treatment attenuates JAK3‐STAT3 and Jag1‐Notch4‐Hey1 signaling and reduces CX3CR1+Ly6C− monocytic precursor generation and pulmonary CD11b+ DC accumulation, together with reduced Th2 inflammation ...
Yujia He   +10 more
wiley   +1 more source

SNP analysis reveals an evolutionary acceleration of the human-specific microRNAs [PDF]

open access: yes, 2008
MicroRNAs are one class of important gene regulators at the post-transcriptional level by binding to the 3’UTRs of target mRNAs. It has been reported that human microRNAs are evolutionary conserved and show lower single nucleotide polymorphisms ...
Qipeng Zhang, Qinghua Cui, Ming Lu
core  

SNP-specific genotype frequencies for cases (YWC) and controls (CGEMS).

open access: yes, 2019
SNP-specific genotype frequencies for cases (YWC) and controls (CGEMS).
Bryce G. Larson (6733730)   +20 more
core   +1 more source

Caffeinated Beverages—Unveiling Their Impact on Human Health

open access: yesBeverages
Caffeine is among the most commonly used and consumed stimulants worldwide. It is a naturally occurring stimulant mainly found in coffee and tea. It is also present in sweetened beverages, which are very popular among young people.
Beáta Čižmárová   +2 more
doaj   +1 more source

Single‐Cell RNA Editing Identifies T Cell ADAR1 as a Key Regulator of Immune Exhaustion and Anti‐PD‐1 Resistance in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
Single‐cell RNA editing analysis identifies ADAR1 as a regulator of dysfunctional T cell states in colorectal cancer. Elevated ADAR1 activity promotes T cell exhaustion and impairs antitumor immunity partly through TGF‐β‐SMAD signaling, contributing to anti‐PD‐1 resistance and highlighting T cell ADAR1 as a potential therapeutic target and biomarker ...
Da Kang   +10 more
wiley   +1 more source

Genome-wide significance for dense SNP and resequencing data.

open access: yes, 2008
The problem of multiple testing is an important aspect of genome-wide association studies, and will become more important as marker densities increase.
Whittaker, John C   +4 more
core   +1 more source

Utility of the pooling approach as applied to whole genome association scans with high-density Affymetrix microarrays. [PDF]

open access: yes, 2010
Background: We report an attempt to extend the previously successful approach of combining SNP (single nucleotide polymorphism) microarrays and DNA pooling (SNP-MaP) employing high-density microarrays.
Farmer, A.   +90 more
core   +1 more source

Fluorescence biomarkers of malignant melanoma detectable in urine

open access: yesOpen Chemistry, 2020
Malignant melanoma (MM) is a cancerous transformation of melanocytes. It is a disease with the worst response to therapy and, compared to other malignancies, presents much earlier with metastases.
Špaková Ivana   +3 more
doaj   +1 more source

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