In Silico Prediction and Molecular Docking of SNPs in NRP1 Gene Associated with SARS-COV-2 [PDF]
, 2023 Ebru Özkan Oktay +3 more
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Connexin 26 Functions as a Direct Transcriptional Regulator During the Cochlea Development
Advanced Science, EarlyView.Connexin26 can not only form intercellular channels that mediate rapid communication on the cell membrane, but also enter the nucleus as a transcription factor to directly regulate the transcription of nuclear genes. In the developing cochlea, Cx26 can control the maturation of the molecular scissor ADAM10 by regulating the transcription of TspanC8 ...
Xiaozhou Liu +8 more
wiley +1 more source
Advanced Science, EarlyView.These findings elucidated the crucial role of the “SVs‐3D genome remodeling‐epigenetic modifications‐gene expression” cascade regulatory network in cotton fiber domestication, offering both a theoretical foundation and genetic resources for molecular design breeding in fiber crops.
Lei Shao +11 more
wiley +1 more source
Population structure and genetic basis of the agronomic traits of upland cotton in China revealed by a genome‐wide association study using high‐density
, 2017 Cong Huang +7 more
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Evaluation and SNP typing of DNA from ultraviolet-irradiated human bloodstains using TaqMan assay [PDF]
, 2021 Jian Tie, Seisaku Uchigasaki, Eiji Isobe
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A Trypsin‐Like Serine Protease ZmNAL1a Fine‐Tunes Maize Floral Transition and Flowering Time
Advanced Science, EarlyView.This study identifies a trypsin‐like serine protease, ZmNAL1a, that moves from leaves to the shoot apical meristem. ZmNAL1a promotes the floral transition by degrading TOPLESS‐like corepressor REL2, which thereby enhances the expression of key flowering genes through elevating histone acetylation and relieving REL2–ZmEREBP147‐mediated transcriptional ...
Nan Li +15 more
wiley +1 more source
Cancer‐Like Fragmentomic Characteristics of Somatic Variants in Cell‐Free DNA
Advanced Science, EarlyView.We report that in non‐cancerous subjects, cell‐free (cfDNA) molecules harboring somatic variants exhibit cancer‐like fragmentomic characteristics associated with clonal hematopoiesis. Importantly, these somatic variant‐associated fragmentomic aberrations are more pronounced in cancer patients. Leveraging such somatic variant‐associated signals in cfDNA,
Zhenyu Zhang +12 more
wiley +1 more source
Novel surfactant C variant c.325–47_374del without response to hydroxychloroquine treatment
Respiratory Medicine Case ReportsPathogenic variants of SP-C, which cause various lung diseases with varying ages of onset, are inherited in an autosomal dominant manner or appear de novo as new mutations. We present a case of fatal respiratory failure in a female infant.
Simona Drobnakova +6 more
doaj +1 more source
16. správa Faunistickej komisie Slovenskej ornitologickej spoločnosti/BirdLife Slovensko / The 16th report of the Rarities Committee of the Slovak Ornithological Society/BirdLife Slovakia [PDF]
Tichodroma, 2016 In 2015, the Rarities Committee of the Slovak Ornithological Society/BirdLife Slovakia reviewed 64 records, of which 57 were accepted in the category A, 1 in category C, one record in category D, three records in category E and one breeding record. Two
Richard KVETKO +1 more
doaj
Meta‐GWAS of Pig Semen Quality Traits Reveals Conserved Genes Regulating Mammalian Fertility
Advanced Science, EarlyView.This study incorporated 14 210 individuals to perform a GWAS meta‐analysis of six semen quality traits. The GWAS meta‐analysis identifies 234 GWAS loci associated with semen quality traits. The incorporation with a functional genomics resource explains potential genetic regulation of ∼40% GWAS signals underlying semen quality traits.
Qing Lin +26 more
wiley +1 more source