Results 21 to 30 of about 313,511 (298)
Life, 2023 Osteoarthritis (OA) is the most common degenerative disease of the connective tissue of the human musculoskeletal system. Despite its widespread prevalence, there are many limitations in its diagnosis and treatment.
Marko Moravek +2 more
doaj +1 more source
SNP-SNP interactions in breast cancer susceptibility [PDF]
BMC Cancer, 2006 AbstractBackgroundBreast cancer predisposition genes identified to date (e.g., BRCA1 and BRCA2) are responsible for less than 5% of all breast cancer cases. Many studies have shown that the cancer risks associated with individual commonly occurring single nucleotide polymorphisms (SNPs) are incremental.
Laurent Briollais +12 more
openaire +5 more sources
SNP interaction pattern identifier (SIPI): an intensive search for SNP–SNP interaction patterns [PDF]
Bioinformatics, 2016 Abstract Motivation Testing SNP–SNP interactions is considered as a key for overcoming bottlenecks of genetic association studies. However, related statistical methods for testing SNP–SNP interactions are underdeveloped.
Adam S. Kibel +47 more
openaire +6 more sources
SNP locator: a candidate SNP selection tool [PDF]
International Journal of Data Mining, Modelling and Management, 2013 [Abstract] In this work, a data integration approach using a federated model based on a service oriented architecture (SOA) is presented. The BioMOBY middleware was used to implement each service which is part of the integration process. As an example of usage of this architecture, a web tool for candidate SNP selection has been developed.
Seoane, José A. +5 more
openaire +3 more sources
Co-Encapsulated Synbiotics and Immobilized Probiotics in Human Health and Gut Microbiota Modulation
Foods, 2021 Growing interest in the development of innovative functional products as ideal carriers for synbiotics, e.g., nutrient bars, yogurt, chocolate, juice, ice cream, and cheese, to ensure the daily intake of probiotics and prebiotics, which are needed to ...
Monika Kvakova +3 more
doaj +1 more source
KLK3 SNP–SNP interactions for prediction of prostate cancer aggressiveness [PDF]
Scientific Reports, 2021 AbstractRisk classification for prostate cancer (PCa) aggressiveness and underlying mechanisms remain inadequate. Interactions between single nucleotide polymorphisms (SNPs) may provide a solution to fill these gaps. To identify SNP–SNP interactions in the four pathways (the angiogenesis-, mitochondria-, miRNA-, and androgen metabolism-related pathways)
Hui-Yi Lin +73 more
openaire +8 more sources
Serum cholesterol is a significant and independent mortality predictor in liver cirrhosis patients
Annals of Hepatology, 2013 Background and Aim. Accurate assessment of cirrhotic patient’s prognosis is essential for decisions regarding the course of treatment. Therefore we aimed to confirm and quantify the predictive value of serum cholesterol and serum triglycerides in liver ...
Martin Janičko +3 more
doaj +1 more source
Journal of Investigative Dermatology, 2005 Imagine a deck of new cards perfectly sequenced from One of Clubs to the Ace of Spades. Shuffle once (overhand method), and most cards are still in order, e.g., ... 9, 10, Jack, King, Queen, Ace of Spades. Shuffle twice, three times, and so on and more and more randomness is introduced into the deck. Cards that are juxtaposed next to one another, e.g.,
openaire +3 more sources
NABIC SNP: an integrated database for SNP markers [PDF]
Bioinformation, 2015 The National Agricultural Biotechnology Information Center (NABIC) constructed a web-based database to provide information about 54,310 single nucleotide polymorphisms (SNPs) identified in the seven species in a high-throughput manner. The database consists of three major functional categories: SNP marker search, detailed information viewer and ...
Chang-Kug Kim +3 more
openaire +2 more sources
Microarrays, 2016 The papers published in this Special Issue “SNP arrays” (Single Nucleotide Polymorphism Arrays) focus on several perspectives associated with arrays of this type. The range of papers vary from a case report to reviews, thereby targeting wider audiences working in this field. The research focus of SNP arrays is often human cancers but this Issue expands
openaire +2 more sources