Results 31 to 40 of about 303,688 (298)
Articular cartilage has limited capacity for natural regeneration and repair. In the present study, we evaluated kartogenin (KGN), a bioactive small heterocyclic molecule, for its effect on in vitro proliferation and chondrogenic differentiation of human
Timea Spakova+5 more
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In this study, the three SNPs (rs1800686, rs3765459 and rs4810485) of CD40 gene were analyzed by multiplex polymerase chain reaction (PCR) combined with next-generation sequencing methods in 476 patients with primary cervical cancer, 744 patients with SIL and 504 healthy females.
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Genome-scale networks can now be reconstructed based on high-throughput data sets. Mathematical analyses of these networks are used to compute their candidate functional or phenotypic states. Analysis of functional states of networks shows that the activity of biochemical reactions can be highly correlated in physiological states, forming so-called co ...
Jamshidi, Neema, Palsson, Bernhard Ø
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Optimisation of urine sample preparation for shotgun proteomics
Urine reflects the renal function and urinary and kidney systems, but it may also reflect the presence of cancer in other parts of the body. Urine also has potential for providing prognostic information during therapeutic treatments thanks to non ...
Tkáčiková Soňa+2 more
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The Importance of Natural Antioxidants in Female Reproduction
Oxidative stress (OS) has an important role in female reproduction, whether it is ovulation, endometrium decidualization, menstruation, oocyte fertilization, or development andimplantation of an embryo in the uterus.
Janka Vašková+7 more
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Importance of Retesting for the Final Diagnosis of Post-Stroke Cognitive Impairment
Background and Objectives: Post-stroke cognitive impairment (PSCI) has been defined as all problems in cognitive function that occur following a stroke.
Dominik Koren+3 more
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Genomic duplications are important sources of structural change and gene innovation. In humans, the most recent and highly identical sequences (>90% homology, >1 kb long) are known as segmental duplications (SDs). Single-nucleotide variants or single-nucleotide polymorphisms within SDs have not been systematically assessed due to limitations around ...
Shapour Jalilzadeh+3 more
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High Prevalence of Clostridioides difficile Ribotype 176 in the University Hospital in Kosice
Dysbiosis of the gut microbiota, caused by antibiotics, plays a key role in the establishment of Clostridioides difficile CD). Toxin-producing strains are involved in the pathogenesis of Clostridioides difficile infection (CDI), one of the most common ...
Katarina Curova+9 more
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This month's Genome Watch highlights new perspectives on polygenic adaptation and its consequences for fitness in microbial populations.
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Testing SNPs and sets of SNPs for importance in association studies [PDF]
A major goal of genetic association studies concerned with single nucleotide polymorphisms (SNPs) is the detection of SNPs exhibiting an impact on the risk of developing a disease. Typically, this problem is approached by testing each of the SNPs individually.
Ingo Ruczinski+2 more
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