Results 41 to 50 of about 303,688 (298)

No association between nest-box size and breeding parameters in White-throated Dipper (Cinclus cinclus) [PDF]

Tichodroma
Nest-box size itself may influence clutch size. In this study, we analysed the variation in clutch size and brood size (number of fledglings at ringing) in relation to nest-box size in the White-throated Dipper.
Miroslav Fulín, Michal Revický, Vladimír Kĺč, Vladimíra Kĺčová Kunštárová, Benjamín Jarčuška   +4 more
doaj   +1 more source

The Epidemiology of Primary Biliary Cholangitis in European Countries: A Systematic Review and Meta-Analysis

Canadian Journal of Gastroenterology and Hepatology, 2021
Background. Primary biliary cholangitis (PBC) is a chronic autoimmune cholestatic liver disease with wide ranges of reported incidence and prevalence. Aim. To map the incidence and prevalence of PBC in European countries from 2000 through 2020.
Jakub Gazda, Sylvia Drazilova, Martin Janicko, Peter Jarcuska   +3 more
doaj   +1 more source

Mesenchymal Stem Cells in the Treatment of Human Spinal Cord Injury: The Effect on Individual Values of pNF-H, GFAP, S100 Proteins and Selected Growth Factors, Cytokines and Chemokines

Current Issues in Molecular Biology, 2022
At present, there is no effective way to treat the consequences of spinal cord injury (SCI). SCI leads to the death of neural and glial cells and widespread neuroinflammation with persisting for several weeks after the injury.
Lucia Slovinska, Denisa Harvanova, Jana Janockova, Jana Matejova, Peter Cibur, Marko Moravek, Timea Spakova, Jan Rosocha   +7 more
doaj   +1 more source

MicroRNAs, SNPs and Cancer [PDF]

Journal of Nucleic Acids Investigation, 2011
MiRNAs are probable regulators of cell events such as differentiation, propagation and apoptosis. These cellular phenomena are also associated with benign and malignant tumor cells, therefore, it is presumed that miRNAs act as natural oncogenes or tumor suppressor genes.
Peng Jin, Angela Vitale, Huiping Tan
openaire   +3 more sources

Lower Viral Response to Pegylated Interferon Alpha 2a Treatment of Chronic Hepatitis B in Roma People in Eastern Slovakia

Gastroenterology Research and Practice, 2016
Aim. To evaluate the compliance and virological response to pegylated interferon alpha 2a treatment of chronic hepatitis B in Roma population compared to majority Caucasian population in Slovakia. Methods. Retrospective evaluation of a cohort of all Roma
Sylvia Drazilova, Martin Janicko, Pavol Kristian, Ivan Schreter, Branislav Kucinsky, Marek Kozlej, Ivana Hockickova, Peter Jarcuska   +7 more
doaj   +1 more source

Electrochemical SNP detection [PDF]

Nucleic Acids Symposium Series, 2006
Detection of mismatched base on a DNA duplex, which is important for the search of the heterozygote, achieved by the comparison with the reactivity of ferrocenylcarbodiimide (1) developed by our group. Mismatched thymine base on the 30-meric DNA duplex as a model of SNPs in lipoprotein lipase (LPL) gene, could react with 1 in 20 mM borate buffer (pH 8 ...
Sadayoshi Watanabe, Michinori Waki, Shigeori Takenaka, Kosuke Mukumoto, Takahiko Nojima   +4 more
openaire   +3 more sources

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Specific Urinary Metabolites in Malignant Melanoma

Medicina, 2019
Background and objectives: Melanin, which has a confirmed role in melanoma cell behaviour, is formed in the process of melanogenesis and is synthesized from tryptophan, L-tyrosine and their metabolites.
Marcela Valko-Rokytovská, Beáta Hubková, Anna Birková, Jana Mašlanková, Marek Stupák, Marianna Zábavníková, Beáta Čižmárová, Mária Mareková   +7 more
doaj   +1 more source