Results 101 to 110 of about 23,427,651 (311)

From an SNP to a Disease: A Comprehensive Statistical Analysis [PDF]

Structure, 2015
Understanding and linking at the molecular level a disease phenotype to a specific genotype often requires going through a protein structure and function. In this issue of Structure, Gao et al. (2015) perform large scale analysis of available sequences and structural data for more than 6000 mutants representing more than 600 proteins to uncover some ...
openaire   +2 more sources

Supramolecular Zinc–Polyphenol Coordination Assemblies Mitigate Colonic Inflammation by Regulating Mucosal Barrier and Microbiome

Advanced Science, EarlyView.
A carrier‐free zinc‐coordinated polyphenol nanoplatform (ZnCA NPs) is designed as an “all‐in‐one” therapeutic strategy for intestinal inflammation. The ZnCA NPs exhibit enhanced colonic accumulation and broad‐spectrum reactive oxygen and nitrogen species scavenging.
Qiwen Xie, Mai Ye, Xuexia Liu, Jing Wang, Ying Chen, Lu Tan, Jinheng Fu, Xiaochang Huang   +7 more
wiley   +1 more source

Proteogenomic Profiling of Idiopathic Pulmonary Arterial Hypertension Identifies Sex‐Differential Proteins and Candidate Therapeutic Targets

Advanced Science, EarlyView.
An integrated proteogenomic analysis of 44,137 predominantly European‐ancestry UK Biobank participants aged 40–69 years identifies 12 robust proteins associated with idiopathic pulmonary arterial hypertension. These proteins define a high‐mortality molecular endotype, support early detection and mortality prediction, reveal sex‐differential proteomic ...
Xinjie Lin, Yangchang Zhang, Yang Pu, Duanke Liu, Tao Lei, Kai Ma, Qiyu He, Zheng Dou, Yuze Liu, Dengyuan Liu, Yinge He, Yanshang Wang, Xiaojiao Zheng, Yanbing Ma, Jianrong Zhou, Weiding Zhai, Binbin Su, Li Chen, Shoujun Li   +18 more
wiley   +1 more source

Meta-analysis of the association between adiponectin SNP 45, SNP 276, and type 2 diabetes mellitus.

PLoS ONE, 2020
ObjectiveThe present study aimed to determine whether the polymorphisms at rs2241766 and rs1501299 on the ADIPOQ gene were related to the susceptibility of type 2 diabetes mellitus (T2DM).MethodsEight databases, PubMed, GWAS, Embase, Lochrane, Ebsco ...
Yuwei Dong, Gongping Huang, Xin Wang, Zhaoming Chu, Jingzhi Miao, Houwen Zhou   +5 more
doaj   +1 more source

Overview of SNP analysis.

, 2018
Overview of SNP analysis.
Mary T. Bessesen (248816), Daniel N. Frank (158306), Jeanne B. Benoit (5172311)   +2 more
core   +1 more source

Transposable Element Dynamics Drive the Genomic Evolution and Phenotypic Diversification of Allotetraploid Common Carp

Advanced Science, EarlyView.
By integrating 516 whole‐genome resequencing datasets and 236 transcriptomes of allotetraploid common carp, this study establishes the first population‐scale atlas of transposable element (TE) variation in teleost species. TE bursts, relaxed purifying selection, and lineage‐specific loss of ancient insertions shape genome evolution and phenotypic ...
Shuimu Hu, Zhou Jiang, Lin Chen, Gowena Ling Yi Goh, Weijing Li, Qian He, Xintong Chen, Rui Li, Yuxuan Liu, Ning Li, Tao Zhou, Peng Xu   +11 more
wiley   +1 more source

Silver nanoparticles enhance the vase life of cut roses by regulating antioxidant defense systems and inhibiting microbial clogging

Scientia Horticulturae
Despite the well-documented antioxidant and antimicrobial properties of silver nanoparticles (SNP), their application research in prolonging the vase life of cut flowers has remained limited.
Xuanyu Zhang, Yuyang Wu, Jun Zhu, Chunyuan Chen, Ruoxi Wang, Jiayi Song, Jingjing Zhang, Yu Zhang, Jinhua Zou   +8 more
doaj   +1 more source

Target sequencing reveals genetic diversity, population structure, core-SNP markers, and fruit shape-associated loci in pepper varieties

BMC Plant Biology, 2019
Background The widely cultivated pepper (Capsicum spp.) is one of the most diverse vegetables; however, little research has focused on characterizing the genetic diversity and relatedness of commercial varieties grown in China.
Heshan Du, Jingjing Yang, Bin Chen, Xiaofen Zhang, Jian Zhang, Kun Yang, Sansheng Geng, Changlong Wen   +7 more
doaj   +1 more source

Summary of SNP analysis.

, 2015
Summary of SNP analysis.
Takeshi Inoue (208656), Shigenobu Yazawa (116528), Yoshihiko Umesono (829049), Tetsutaro Hayashi (394802), Eri Kawaguchi (829048), Kiyokazu Agata (30383), Kazutaka Hosoda (829047), Osamu Nishimura (106269)   +7 more
core   +1 more source

Development of a temperature-switch PCR-based SNP typing method for Mycobacterium ulcerans [PDF]

, 2012
Mycobacterium ulcerans (M. ulcerans), the causative agent of the devastating skin disease Buruli ulcer (BU), is characterized by an extremely low level of genetic diversity.
Danso Emelia, Röltgen, K., Gerd Pluschke, Pluschke Gerd, Yeboah-Manu, D., Katharina Röltgen, Dorothy Yeboah-Manu (120059), Gerd Pluschke (7855), Emelia Danso, Katharina Röltgen (120045), Danso, E., Pluschke, G., Kobina Assan-Ampah, Emelia Danso (120054), Dorothy Yeboah-Manu, Kobina Assan-Ampah (120049), Yeboah-Manu Dorothy, Assan-Ampah Kobina, Assan-Ampah, K., Röltgen Katharina, Danso E, Assan-Ampah K, Pluschke G, Yeboah-Manu D, Röltgen K   +24 more
core   +1 more source