Results 81 to 90 of about 23,427,651 (311)

LD₂SNPing: linkage disequilibrium plotter and RFLP enzyme mining for tag SNPs

BMC Genetics, 2009
Background Linkage disequilibrium (LD) mapping is commonly used to evaluate markers for genome-wide association studies. Most types of LD software focus strictly on LD analysis and visualization, but lack supporting services for genotyping.
Cheng Yu-Huei, Chang Yan-Jhu, Chuang Li-Yeh, Chang Hsueh-Wei, Hung Yu-Chen, Chen Hsiang-Chi, Yang Cheng-Hong   +6 more
doaj   +1 more source

SNP analysis reveals an evolutionary acceleration of the human-specific microRNAs [PDF]

, 2008
MicroRNAs are one class of important gene regulators at the post-transcriptional level by binding to the 3’UTRs of target mRNAs. It has been reported that human microRNAs are evolutionary conserved and show lower single nucleotide polymorphisms ...
Qipeng Zhang, Qinghua Cui, Ming Lu
core  

rSNPBase 3.0: an updated database of SNP-related regulatory elements, element-gene pairs and SNP-based gene regulatory networks

, 2017
Here, we present the updated rSNPBase 3.0 database (http://rsnp3.psych.ac.cn), which provides human SNP-related regulatory elements, element-gene pairs and SNP-based regulatory networks.
Jing Wang, Liyuan Guo, Guo, Liyuan, Wang, Jing   +3 more
core   +1 more source

MDR analysis for SNP-SNP interaction in NOS3 with EH risk.

, 2023
MDR analysis for SNP-SNP interaction in NOS3 with EH risk.
Chanjuan Wang (14593476), Xiaolan Qi (11954006), Yanhong Li (661033), Xiaoyan Diao (14593473), Juhui Song (12517339), Ting Zhang (102583), Zhizhong Guan (844404), Yan He (116705), Ansu Zhao (14593470), Ruichao Li (3180570)   +9 more
core   +1 more source

Conditionally Significant eQTL and TWAS Analyses Identify MsRD26 as a Major Candidate Positive Regulator of Salt Tolerance in Medicago sativa L

Advanced Science, EarlyView.
Salt stress significantly impacts plant growth. Through population transcriptome, eQTL and TWAS analyses, we identified several candidate genes potentially associated with salt stress response. Functional assays suggested that some of these genes may contribute to salt tolerance.
Lin Chen, Yuqi Zhang, Xinyue Ma, Jinpeng Bi, Fei He, Li Zhao, Haiyue Lei, Zhengqin Xiao, Xue Wang, Tiejun Zhang, Ruicai Long, Junmei Kang, Qingchuan Yang   +12 more
wiley   +1 more source

SNP-SNP interactions identified by Statistical Epistasis Network Analysis.

, 2012
SNP-SNP interactions identified by Statistical Epistasis Network Analysis.
Margaret R. Karagas (65123), Xifeng Wu (110961), Jian Gu (23649), Yuanqing Ye (29040), Sam A. Tanyos (110939), Jiang Gui (110929), Jason H. Moore (107452), Angeline S. Andrew (65118), Zhongze Li (110957), Alan R. Schned (110935), Ting Hu (110925), Carmen J. Marsit (109106), Eben M. Pendleton (110943), Elaine V. Morlock (110949), Rebecca A. Mason (110945), Karl T. Kelsey (60825), Michael S. Zens (110953)   +16 more
core   +1 more source

Drought Stress Mediated Changes in Food Crops: Mechanisms and Remediation Strategies

Advanced Science, EarlyView.
This work presents a multi‐scale framework for flavonoid‐mediated drought tolerance in staple food crops, integrating ROS redox regulation, antioxidant defense, rhizosphere microbial interactions, and sustainable agronomic practices. This interdisciplinary model provides core insights to develop climate‐resilient cropping systems and enhance global ...
Xiaoyi Duan, Litao Wang, Tuuli‐Marjaana Koski, Lizhe An, Thomas Efferth, Yujie Fu   +5 more
wiley   +1 more source

SNPs with High Linkage Disequilibrium Increase the Explained Genetic Variance and the Reliability of Genomic Predictions

Animals
The objective of this study was to compare the proportion of explained genetic variance (EXGV) and the reliability of genomic breeding values (GBVs) predictions for milk yield (MY), fat yield (FY), protein yield (PY) fat percentage (FP), protein ...
José Guadalupe Cortes-Hernández, Felipe de Jesús Ruiz-López, Francisco Peñagaricano, Hugo H. Montaldo, Adriana García-Ruiz   +4 more
doaj   +1 more source

Detection of genetic association and functional polymorphisms of UGDH affecting milk production trait in Chinese Holstein cattle

BMC Genomics, 2012
Background We previously localized a quantitative trait locus (QTL) on bovine chromosome 6 affecting milk production traits to a 1.5-Mb region between BMS483 and MNB-209 via genome scanning followed by fine mapping.
Xu Qing, Mei Gui, Sun Dongxiao, Zhang Qin, Zhang Yuan, Yin Cengceng, Chen Huiyong, Ding Xiangdong, Liu Jianfeng   +8 more
doaj   +1 more source

Nano Proton Scavengers Modulate Endosomal pH to Inhibit Microglial Activation and Enhance Stroke Recovery

Advanced Science, EarlyView.
Amphiphilic sulfonated chitosan nanoparticles buffer endo/lysosomal acidity in microglia by limiting V‐ATPase membrane recruitment and restoring endosomal homeostasis. Following systemic administration, they accumulate in the ischemic hemisphere partly through association with infiltrating immune cells, suppress TLR3/IRF3 and TLR4/NF‐κB signaling ...
Xuanlin Wang, Yujing Shi, Zehua Gao, Jing Wang, Changsheng Liu   +4 more
wiley   +1 more source