Results 61 to 70 of about 23,427,651 (311)
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
BioTechniques, 2001 Analysis of single nucleotide polymorphisms (SNPs) is a rapidly growing field of research that provides insights into the most common type of differences between individual genomes.
W. Pusch +4 more
doaj +1 more source
SNP set association analysis for genome-wide association studies. [PDF]
PLoS ONE, 2013 Genome-wide association study (GWAS) is a promising approach for identifying common genetic variants of the diseases on the basis of millions of single nucleotide polymorphisms (SNPs).
Min Cai +9 more
doaj +1 more source
Statistical Applications for SNPs Analysis
Chem-Bio Informatics Journal, 2006 A subset of single nucleotide polymorphisms (SNPs) can be used to capture the majority of the information of genotype-phenotype association studies. The primary issue that we should discuss in SNPs analysis is how one can select a particular subset of SNPs while maximizing the power of detecting a significant association.
Yang, Woosung, Nakaya, Jun
openaire +2 more sources
Augmenting and Assaying Nav1.1 Protein Quantity for Dravet Syndrome Therapy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Dravet Syndrome (DS) is a developmental and epileptic encephalopathy predominantly caused by heterozygous loss‐of‐function variants in SCN1A, which encodes Nav1.1. Conserved upstream open reading frames (uORFs) in SCN1A were validated to regulate translation in reporter assays, demonstrating the therapeutic viability of increasing Nav1.1 from ...
Aiswarya Saravanan +7 more
wiley +1 more source
Weighted SNP set analysis in genome-wide association study. [PDF]
PLoS ONE, 2013 Genome-wide association studies (GWAS) are popular for identifying genetic variants which are associated with disease risk. Many approaches have been proposed to test multiple single nucleotide polymorphisms (SNPs) in a region simultaneously which ...
Hui Dai +9 more
doaj +1 more source
Analisis Peta Mutu Pendidikan SMA Kabupaten Lombok Tengah Tahun 2020
Jurnal Paedagogy, 2022 The purpose of this study is to produce a portrait of the educational quality of Central Lombok High School in 2020 through the process of data collection, environmental analysis, as well as recommendations and quality improvement strategies referring to
Mohamad Tohar
doaj +1 more source
MDR analysis for SNP–SNP interaction in CYP4F2 with HAPE risk.
, 2023 MDR analysis for SNP–SNP interaction in CYP4F2 with HAPE risk.
Haiyuan Wang (1721239) +7 more
core +1 more source
Advanced Science, EarlyView.The burden quantitative trait locus (bQTL) analysis integrates epidemiological data from GBD study with genotype of 2 621 978 SNPs from 2414 individuals in 1000 Genomes Project across 20 countries. rs7633471 shows the strongest effect that each increase in centi‐allele frequency of the allele C associated with 10.00 decrease of age‐standardized ...
Chen Sun +27 more
wiley +1 more source
Animals, 2022 Fecundity is an important economic trait in sheep that directly affects their economic and productive efficiency. Our study aimed to identify SNP loci associated with sheep puberty or litter size which could be used in future breeding programs to improve
Zhishuai Zhang +7 more
doaj +1 more source