Results 41 to 50 of about 23,427,651 (311)
SNP-SNP entropy-based interaction network of 11 ERAP1 SNPs in 748 Iranian BD patients.
, 2020 SNP-SNP entropy-based interaction network of 11 ERAP1 SNPs in 748 Iranian BD patients.
Parisa Riahi (8407764) +9 more
core +1 more source
The Usage of an SNP-SNP Relationship Matrix for Best Linear Unbiased Prediction (BLUP) Analysis Using a Community-Based Cohort Study [PDF]
Genomics & Informatics, 2014 Best linear unbiased prediction (BLUP) has been used to estimate the fixed effects and random effects of complex traits. Traditionally, genomic relationship matrix-based (GRM) and random marker-based BLUP analyses are prevalent to estimate the genetic ...
Young-Sup Lee +3 more
doaj +1 more source
eSNPO: An eQTL-based SNP Ontology and SNP functional enrichment analysis platform [PDF]
Scientific Reports, 2016 AbstractGenome-wide association studies (GWASs) have mined many common genetic variants associated with human complex traits like diseases. After that, the functional annotation and enrichment analysis of significant SNPs are important tasks. Classic methods are always based on physical positions of SNPs and genes.
Jin Li +10 more
openaire +2 more sources
Журнал микробиологии, эпидемиологии и иммунобиологииIntroduction. The Tuva mountain plague focus (TMPF) in Russia has been continuously epizootically active since its discovery in 1964. The strains of Yersinia pestis isolated in this focus belong to the phylogenetic lineage 4.ANT of the antique biovar of ...
Elizaveta V. Stankovtseva +8 more
doaj +1 more source
SNP-PRAGE: SNP-based parametric robust analysis of gene set enrichment [PDF]
BMC Systems Biology, 2011 Abstract Background The current genome-wide association (GWA) analysis mainly focuses on the single genetic variant, which may not reveal some the genetic variants that have small individual effects but large joint effects.
Jaehoon Lee +4 more
openaire +2 more sources
Genetic analysis of products of conception using a HLPA/SNP-array strategy
Molecular Cytogenetics, 2019 Background Fetal chromosomal abnormalities was the most frequent cause of miscarriage, and the traditional testing method G-banded karyotyping has limitations.
Jun Mao +6 more
doaj +1 more source
SNP analysis using catacleave probes
Journal of Clinical Laboratory Analysis, 2008 AbstractCataCleave” probes are catalytically cleavable fluorescence probes having a chimeric deoxyribonucleic acid (DNA)‐ribonucleic acid (RNA)‐DNA structure that can be used for real‐time detection of single nucleotide polymorphisms (SNPs), insertions, and deletions. Fluorescent donor emission is normally quenched by Förster resonance energy transfer (
John J, Harvey +3 more
openaire +3 more sources
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source