Results 171 to 180 of about 215,087 (323)

Amyloid‐Related Imaging Abnormality (ARIA) Beyond the APOE‐ε4 Allele

Chronic Diseases and Translational Medicine, EarlyView.
Mechanism of action of monoclonal antibodies targeting Aβ in the treatment of AD. (A) Targets of various mAbs. (B) Mechanism of monoclonal antibody‐mediated clearance of Aβ. mAbs facilitate the clearance of Aβ by enhancing microglial‐mediated phagocytosis through the upregulation of TREM2 expression.
Valentinus Besin, Farizky Martriano Humardani, Fenny Lanawati Yudiarto, Paulus Anam Ong, Sulistyo Emantoko Dwi Putra, Ratih Asmana Ningrum   +5 more
wiley   +1 more source

Development of a 135K SNP genotyping array for Actinidia arguta and its applications for genetic mapping and QTL analysis in kiwifruit. [PDF]

Plant Biotechnol J, 2023
Wang R, Xing S, Bourke PM, Qi X, Lin M, Esselink D, Arens P, Voorrips RE, Visser RGF, Sun L, Zhong Y, Gu H, Li Y, Li S, Maliepaard C, Fang J.   +15 more
europepmc   +1 more source

Faculty Opinions recommendation of L-RCA (ligation-rolling circle amplification): a general method for genotyping of single nucleotide polymorphisms (SNPs).

, 2001
Peter Langridge
openalex   +2 more sources

RAB19, SERPINB9P1, and Pancreatitis in Patients Taking Azathioprine in Routine Clinical Practice: Genome and Transcriptome‐Wide Association Studies

Clinical Pharmacology &Therapeutics, EarlyView.
Azathioprine is used to treat several inflammatory and autoimmune diseases. However, its use is limited by serious adverse events, including acute pancreatitis. Prior studies have found an association between the HLA region and thiopurine‐induced acute pancreatitis (TIAP); however, in clinical practice, many patients with pancreatitis do not meet this ...
Shailja C. Shah, Tyler S. Reese, Laura L. Daniel, Jacy Zanussi, Alyson L. Dickson, Puran Nepal, Ran Tao, Tyne Miller‐Fleming, Peter Straub, Jennifer Maizel, Adriana M. Hung, Wei‐Qi Wei, Elizabeth J. Phillips, Nancy J. Cox, C. Michael Stein, QiPing Feng, Cecilia P. Chung   +16 more
wiley   +1 more source

SNP Genotyping Characterizes the Genome Composition of the New Baisary Fat-Tailed Sheep Breed. [PDF]

Animals (Basel), 2022
Zhumadillayev N, Dossybayev K, Khamzina A, Kapasuly T, Khamzina Z, Tlevlesov N.   +5 more
europepmc   +1 more source

Unraveling Novel Genetic Determinants of Thiopurine Response Via TWAS

Clinical Pharmacology &Therapeutics, EarlyView.
Acute lymphoblastic leukemia (ALL) is the most common childhood cancer. Thiopurines such as 6‐mercaptopurine (6MP) are essential in ALL maintenance therapy. However, dose‐limiting toxicities can significantly disrupt treatment. While genetic variants in TPMT and NUDT15 are known to affect thiopurine response, many patients with normal function ...
Carlotta Bidoli, Wenjian Yang, Seth E. Karol, Marianna Lucafò, Gabriele Stocco, Jun J. Yang   +5 more
wiley   +1 more source

Rapid and accurate SNP genotyping of clonal bacterial pathogens with BioHansel. [PDF]

Microb Genom, 2021
Labbé G, Kruczkiewicz P, Robertson J, Mabon P, Schonfeld J, Kein D, Rankin MA, Gopez M, Hole D, Son D, Knox N, Laing CR, Bessonov K, Taboada EN, Yoshida C, Ziebell K, Nichani A, Johnson RP, Van Domselaar G, Nash JHE.   +19 more
europepmc   +1 more source

A genotype calling algorithm for affymetrix SNP arrays [PDF]

, 2005
Nusrat Rabbee, Terence P. Speed
openalex   +1 more source

GenoStaR: An R Package for Genotype to Star Allele Conversion for Major Cytochrome P450 Family of Genes

Clinical Pharmacology &Therapeutics, EarlyView.
Pharmacogenomics enables the personalization of drug therapy by linking genetic variations to differences in drug metabolism, efficacy, and risk of adverse reactions. Genetic polymorphisms within cytochrome P450 (CYP) genes significantly affect enzyme activity, influencing drug plasma levels, responses, and safety.
Alex J. Coulter, Megana Thamilselvan, James L. Kennedy, Clement C. Zai, Arun K. Tiwari   +4 more
wiley   +1 more source

Role of EFNA1 SNP (rs12904) in Tumorigenesis and Metastasis of Colorectal Cancer: A Bioinformatic Analysis and HRM SNP Genotyping Verification. [PDF]

Asian Pac J Cancer Prev, 2022
Salem E, Keshvari A, Mahdavinezhad A, Soltanian AR, Saidijam M, Afshar S.   +5 more
europepmc   +1 more source