Results 171 to 180 of about 223,459 (323)

Results of logistic regression for the 32 genotyped SNPs.

, 2015
Reedik Mägi, Sean Manning, Ahmed Yousseif, Andrea Pucci, Ferruccio Santini, Efthimia Karra, Giorgia Querci, Caterina Pelosini, Mark I. McCarthy, Cecilia M. Lindgren, Rachel L. Batterham   +10 more
openalex   +2 more sources

Prognostic Implication of CYP2C19 Genotype According to Clinical Risk Stratification After Drug‐Eluting Stent Implantation

Clinical Pharmacology &Therapeutics, EarlyView.
From the nationwide multicenter consortium, 8,163 patients undergoing drug‐eluting stent implantation were classified according to the presence of the CYP2C19 loss‐of‐function (LoF) allele: rapid or normal metabolizers (RMs/NMs) vs. intermediate or poor metabolizers (IMs/PMs), and clinical risk was stratified using the CHADS‐P2A2RC and TRS 2°P scores ...
Hyun Woong Park, Jae‐Hwan Lee, Jin‐Ok Jeong, Diana A. Gorog, Udaya S. Tantry, Byeong‐Keuk Kim, Hyung Joon Joo, Kiyuk Chang, Jin‐Yong Hwang, Young Bin Song, Sung Gyun Ahn, Jung‐Won Suh, Woong Gil Choi, Jung Rae Cho, Jeehoon Kang, Sang Yeub Lee, Hyo‐Soo Kim, Moo Hyun Kim, Do‐Sun Lim, Eun‐Seok Shin, Paul A. Gurbel, Young‐Hoon Jeong, on behalf of the PTRG‐DES Consortium Investigators   +22 more
wiley   +1 more source

Design and validation of a 63K genome-wide SNP-genotyping platform for caribou/reindeer (Rangifer tarandus). [PDF]

BMC Genomics, 2022
Carrier A, Prunier J, Poisson W, Trottier-Lavoie M, Gilbert I, Cavedon M, Pokharel K, Kantanen J, Musiani M, Côté SD, Albert V, Taillon J, Bourret V, Droit A, Robert C.   +14 more
europepmc   +1 more source

Multiplex SNP Genotyping Using SWITCH: Sequence‐Specific Nanoparticle with Interpretative Toehold‐Mediated Sequence Decoding in Hydrogel [PDF]

, 2021
Woongsun Choi, Eunhye Park, Seojin Bae, Kyung‐Hak Choi, Sangeun Han, Kuk‐Hui Son, Do Young Lee, Il‐Joo Cho, Hyejeong Seong, Kyo Seon Hwang, Jwa‐Min Nam, Jungkyu Choi, Hyojin Lee, Nakwon Choi   +13 more
openalex   +1 more source

Lower Dose‐Normalized Tacrolimus Exposure in CYP3A5*6 vs. *3 Loss‐of‐Function Allele Carriers: A Longitudinal Retrospective Real‐World Study in Kidney Transplant Recipients

Clinical Pharmacology &Therapeutics, EarlyView.
Pharmacogenomic research has historically focused on individuals of European ancestry, leading to the underrepresentation of genetic variants common in non‐European populations. This bias is exemplified by CYP3A5*6, a functionally consequential variant common in individuals of African ancestry (MAF: 11–19%) but virtually absent in Europeans (MAF: 0.15%)
Amar D. Levens, Dirk Jan A. R. Moes, Yanick Boer, Aiko P. J. de Vries, Dorottya K. de Vries, Danny van der Helm, Soufian Meziyerh, Dave L. Roelen, Stefan Böhringer, Teun Van Gelder, Jesse J. Swen   +10 more
wiley   +1 more source

Development of a new AgriSeq 4K mid-density SNP genotyping panel and its utility in pearl millet breeding. [PDF]

Front Plant Sci, 2022
Semalaiyappan J, Selvanayagam S, Rathore A, Gupta SK, Chakraborty A, Gujjula KR, Haktan S, Viswanath A, Malipatil R, Shah P, Govindaraj M, Ignacio JC, Reddy S, Singh AK, Thirunavukkarasu N.   +14 more
europepmc   +1 more source

Multiplex SNP Genotyping Using SWITCH: Sequence‐Specific Nanoparticle with Interpretative Toehold‐Mediated Sequence Decoding in Hydrogel (Small 8/2022) [PDF]

, 2022
Woongsun Choi, Eunhye Park, Seojin Bae, Kyung‐Hak Choi, Sangeun Han, Kuk‐Hui Son, Do Young Lee, Il‐Joo Cho, Hyejeong Seong, Kyo Seon Hwang, Jwa‐Min Nam, Jungkyu Choi, Hyojin Lee, Nakwon Choi   +13 more
openalex   +1 more source

Improving Genotype Imputation in High‐Dimensional Pharmacogenomics Using Multiple Imputation: Evaluation with Machine Learning Approaches

Clinical Pharmacology &Therapeutics, EarlyView.
Multiple imputation is well‐established for handling missing data, yet its use in high‐dimensional genetic datasets remains limited. Using pharmacokinetic tuberculosis simulations and SNP data (1000 Genomes Project), we compared machine learning (ML) and traditional approaches (e.g., mean imputation and complete‐case analysis) for imputation and ...
Innocent G. Asiimwe, Tao You, Daniel F. Carr, Munir Pirmohamed, Geraint Davies, Andrea L. Jorgensen, on behalf of the UNITE4TB Consortium   +6 more
wiley   +1 more source

Investigation of mutation load and rate in androgenic mutant lines of rapeseed in early generations evaluated by high-density SNP genotyping. [PDF]

Heliyon, 2023
Gritsenko D, Daurova A, Pozharskiy A, Nizamdinova G, Khusnitdinova M, Sapakhova Z, Daurov D, Zhapar K, Shamekova M, Kalendar R, Zhambakin K.   +10 more
europepmc   +1 more source

Genotypes of Bathymodiolus vent mussels from the Mid-Atlantic Ridge using SNP and mitochondrial markers

, 2016
Corinna Breusing, Robert C. Vrijenhoek, Thorsten B. H. Reusch   +2 more
openalex   +1 more source