Results 21 to 30 of about 97,365 (285)

Temperature Switch PCR (TSP): Robust assay design for reliable amplification and genotyping of SNPs

BMC Genomics, 2009
Background Many research and diagnostic applications rely upon the assay of individual single nucleotide polymorphisms (SNPs). Thus, methods to improve the speed and efficiency for single-marker SNP genotyping are highly desirable.
Mather Diane E, Tabone Tania, Hayden Matthew J   +2 more
doaj   +1 more source

High quality genome-wide genotyping from archived dried blood spots without DNA amplification. [PDF]

PLoS ONE, 2013
Spots of blood are routinely collected from newborn babies onto filter paper called Guthrie cards and used to screen for metabolic and genetic disorders. The archived dried blood spots are an important and precious resource for genomic research.
Krystal R St Julien, Laura L Jelliffe-Pawlowski, Gary M Shaw, David K Stevenson, Hugh M O'Brodovich, Mark A Krasnow, Stanford BPD Study Group   +6 more
doaj   +1 more source

A reference haplotype panel for genome-wide imputation of short tandem repeats. [PDF]

, 2018
Short tandem repeats (STRs) are involved in dozens of Mendelian disorders and have been implicated in complex traits. However, genotyping arrays used in genome-wide association studies focus on single nucleotide polymorphisms (SNPs) and do not readily ...
Fotsing, Stephanie Feupe, Gymrek, Melissa, Mitra, Ileena, Mousavi, Nima, Saini, Shubham   +4 more
core   +3 more sources

Evolutionary Computation-Based Memetic Algorithm Against Genetic Algorithm to Improve PCR-RFLP Assay Primers of SNP Genotyping

IEEE Access, 2018
A genetic algorithm (GA) combines the restriction enzyme mining core of single nucleotide polymorphism (SNP) restriction fragment length polymorphism (RFLP) to design polymerase chain reaction (PCR)-RFLP primer pairs for SNP-based genotyping with ...
Yu-Huei Cheng, Ching-Ming Lai, Jiashen Teh, Che-Nan Kuo   +3 more
doaj   +1 more source

The development of a novel SNP genotyping assay to differentiate cacao clones [PDF]

, 2019
In this study, a double-mismatch allele-specific (DMAS) qPCR SNP genotyping method has been designed, tested and validated specifically for cacao, using 65 well annotated international cacao reference accessions retrieved from the Center for Forestry ...
Coppieters, Frauke, De Wever, Jocelyn, Dewettinck, Koen, Everaert, Helena, Lefever, Steve, Messens, Kathy, Rottiers, Hayley   +6 more
core   +1 more source

Development of a high-density sub-species-specific targeted SNP assay for Rocky Mountain bighorn sheep (Ovis canadensis canadensis) [PDF]

PeerJ
Due to their abundance and relative ease of genotyping, single nucleotide polymorphisms (SNPs) are a commonly used molecular marker for contemporary population genetic and genomic studies. A high-density and cost-effective way to type SNP loci is Allegro
Samuel Deakin, David W. Coltman
doaj   +2 more sources

A High-Density Linkage Map of the Ancestral Diploid Strawberry, Fragaria iinumae, Constructed with Single Nucleotide Polymorphism Markers from the IStraw90 Array and Genotyping by Sequencing [PDF]

, 2016
Fragaria iinumae Makino is recognized as an ancestor of the octoploid strawberry species, which includes the cultivated strawberry, Fragaria ×ananassa Duchesne ex Rozier.
Abebe-Akele, Feseha, Bassil, Nahla V., Davis, Thomas M., Folta, Kevin M., Hancock, James F., Mahoney, Lise L., Sargent, Daniel J., Ward, Judson A., Wood, David J.   +8 more
core   +3 more sources

Single nucleotide polymorphisms in the CDH18 gene affect growth traits in Hu sheep

Animal Research and One Health, EarlyView., 2023
Abstract Growth traits are critical economic traits in sheep. Genetic polymorphism has a great influence on the improvement of sheep traits. The aim of this study was to analyze the effect of cadherin 18 (CDH18) gene polymorphisms on growth traits in Hu sheep.
Tianyi Liu, Yazhen Bi, Jingjing Bao, Mingyu Shang, Wenping Hu, Li Zhang   +5 more
wiley   +1 more source

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization. [PDF]

, 2013
The QT interval, an electrocardiographic measure reflecting myocardial repolarization, is a heritable trait. QT prolongation is a risk factor for ventricular arrhythmias and sudden cardiac death (SCD) and could indicate the presence of the potentially ...
Abecasis, GR, Ackerman, MJ, Adamkova, V, Alonso, A, Arking, DE, Arnar, DO, Asselbergs, FW, Bader, JS, Barc, J, Bardai, A, Beckmann, BM, Behr, ER, Bezzina, CR, Bis, JC, Bobbo, M, Boyer, LA, Bradford, Y, Brandimarto, J, Brion, M, Brown, M, Campbell, H, Cappola, TP, CARe Consortium, Carella, M, Carracedo, A, Caulfield, MJ, Chakravarti, A, Chatel, S, COGENT Consortium, Crotti, L, Cummings, SR, D'Adamo, AP, Dalageorgou, C, Daly, MJ, DCCT/EDIC, de Bakker, PI, de Boer, RA, del Greco M, F, den Hoed, M, Denny, JC, Dominiczak, AF, Dörr, M, Ehret, G, Eijgelsheim, M, Eisele, L, El Mokhtari, NE, Ellinghaus, D, eMERGE Consortium, Emilsson, V, Erbel, R, Evans, DS, Felix, SB, Ferrucci, L, Franco, OH, Franke, A, Franke, L, Frey, N, Fuchsberger, C, Gasparini, P, Ghidoni, A, Gieger, C, Giudicessi, JR, Greiser, KH, Griffin, M, Gudbjartsson, DF, Gudnason, V, Gustafsson, S, Haerting, J, Hamilton, RM, Harris, TB, Hayward, C, Heckbert, SR, Hicks, AA, Hingorani, AD, Hoffmann, P, Hofman, A, Hofman, N, HRGEN Consortium, Huang, H, Hubacek, JA, Hólm, H, Ingelsson, E, Insolia, R, Iorio, A, Isaacs, A, Jamshidi, Y, Johnson, AD, Jula, A, Jöckel, KH, Kao, WH, Kedenko, L, Kellis, M, Kiechl, S, Kivimaki, M, Kluttig, A, Knoflach, M, Kolcic, I, Kontula, KK, Koopmann, TT, Kors, JA, Krijthe, BP, Kronenberg, F, Kumar, RD, Kumari, M, Kyndt, F, Kähönen, M, Kälsch, H, Kääb, S, Lage, K, Lahtinen, AM, Lakatta, EG, Lamina, C, Larson, MG, Launer, LJ, Lee, WK, Lehtimäki, TJ, Lind, L, Liu, Y, Loos, RJ, Lundby, A, Lyytikäinen, LP, Macfarlane, PW, Margulies, K, Marjamaa, A, Markus, MR, Martens, E, Mateo Leach, I, Medeiros-Domingo, A, Meitinger, T, Meyer Zu Schwabedissen, H, Mononen, N, Moravec, CE, Morley, M, Morris, RW, Mulas, A, Munroe, PB, Mühleisen, TW, Müller-Nurasyid, M, Nalls, MA, Naluai, ÅT, Navarro, P, Navis, G, Newhouse, SJ, Newton-Cheh, C, Nicolaides, AN, Nolte, IM, Noseworthy, PA, Nyberg, F, Nöthen, MM, O'Connell, JR, O'Donnell, CJ, Oikarinen, L, Olsen, JV, Oostra, BA, Orrú, M, Padmanabhan, S, Panayiotou, AG, Parsa, A, Paterson, AD, Paulweber, B, Perola, M, Perz, S, Peters, A, Pfeufer, A, Plump, AS, Polašek, O, Porthan, K, Post, WS, Pramstaller, PP, Probst, V, Prucha, H, Psaty, BM, Pulit, SL, Raitakari, OT, Raychaudhuri, S, Ritchie, MD, Roden, DM, Rossin, EJ, Rotter, JI, Rudan, I, Salomaa, V, Samani, NJ, Sanna, S, Scherer, SW, Schlessinger, D, Schott, JJ, Schwartz, PJ, Shuldiner, AR, Sinagra, G, Sinner, MF, Siscovick, DS, Slowikowski, K, Smith, AV, Smith, JG, Snieder, H, Sotoodehnia, N, Spector, TD, Stefansson, K, Strait, JB, Stricker, BH, Strohmer, B, Sundström, J, Syvänen, AC, Tanaka, T, Tarasov, KV, Tester, DJ, Thelle, DS, Thorsteinsdottir, U, Torres, M, Uda, M, Uitterlinden, AG, Ulivi, S, van den Berg, MP, van der Harst, P, van der Vleuten, PA, van Duijn, CM, van Veldhuisen, DJ, Viikari, JS, Völker, U, Waggott, D, Waldenberger, M, Wang, X, Watt, GC, Werdan, K, Whincup, PH, Wild, SH, Wilde, AA, Willeit, J, Wilson, JF, Witteman, JC, Wright, AF, Yin, X, Zelante, L, Zuvich, RL, Ärnlöv, J   +234 more
core   +6 more sources

Characterization of duplicate gene evolution in the recent natural allopolyploid Tragopogon miscellus by next-generation sequencing and Sequenom iPLEX MassARRAY genotyping [PDF]

, 2010
The definitive version is available at www.blackwell-synergy ...
Adams, Adams, Adams, Ainouche, Barbazuk, Bottley, Buggs, Buggs, Buggs, Cannon, Chaisson, Chaudhary, Chen, Chen, Cheung, Cheung, Cook, Cook, Dong, Doyle, Dunstan, Ellegren, Elmer, Emrich, Eveland, Feldman, Ferguson, Flagel, Flagel, Gabriel, Gaeta, Goetz, Guo, Gut, Harr, Hegarty, Hegarty, Hillier, Holt, Hudson, Johnson, Joly, Judd, Kashkush, Kihara, Kim, Kim, Kovarik, Kwok, Levy, Lim, Lim, Liu, Lynch, Margulies, Marth, Matyasek, Mavrodiev, Novaes, Novak, Ownbey, Pavy, Petit, Quackenbush, Renaut, Sadava, Slate, Soltis, Soltis, Soltis, Soltis, Soltis, Song, Stebbins, Stupar, Swanson-Wagner, Tate, Tate, Tate, Udall, Van Bers, Van Tassell, Vera, Wang, Wang, Whittall, Wolf   +86 more
core   +1 more source