Results 21 to 30 of about 125,026 (143)

High quality genome-wide genotyping from archived dried blood spots without DNA amplification. [PDF]

PLoS ONE, 2013
Spots of blood are routinely collected from newborn babies onto filter paper called Guthrie cards and used to screen for metabolic and genetic disorders. The archived dried blood spots are an important and precious resource for genomic research.
Krystal R St Julien, Laura L Jelliffe-Pawlowski, Gary M Shaw, David K Stevenson, Hugh M O'Brodovich, Mark A Krasnow, Stanford BPD Study Group   +6 more
doaj   +1 more source

Evolutionary Computation-Based Memetic Algorithm Against Genetic Algorithm to Improve PCR-RFLP Assay Primers of SNP Genotyping

IEEE Access, 2018
A genetic algorithm (GA) combines the restriction enzyme mining core of single nucleotide polymorphism (SNP) restriction fragment length polymorphism (RFLP) to design polymerase chain reaction (PCR)-RFLP primer pairs for SNP-based genotyping with ...
Yu-Huei Cheng, Ching-Ming Lai, Jiashen Teh, Che-Nan Kuo   +3 more
doaj   +1 more source

Development of a high-density sub-species-specific targeted SNP assay for Rocky Mountain bighorn sheep (Ovis canadensis canadensis) [PDF]

PeerJ
Due to their abundance and relative ease of genotyping, single nucleotide polymorphisms (SNPs) are a commonly used molecular marker for contemporary population genetic and genomic studies. A high-density and cost-effective way to type SNP loci is Allegro
Samuel Deakin, David W. Coltman
doaj   +2 more sources

A machine learning approach for missing persons cases with high genotyping errors

Frontiers in Genetics, 2022
Estimating the relationships between individuals is one of the fundamental challenges in many fields. In particular, relationship.ip estimation could provide valuable information for missing persons cases.
Meng Huang, Muyi Liu, Hongmin Li, Jonathan King, Amy Smuts, Bruce Budowle, Bruce Budowle, Jianye Ge, Jianye Ge   +8 more
doaj   +1 more source

Genetic Diversity and Population Structure in a Vitis spp. Core Collection Investigated by SNP Markers

Diversity, 2020
Single nucleotide polymorphism (SNP) genotyping arrays are powerful tools to measure the level of genetic polymorphism within a population. The coming of next-generation sequencing technologies led to identifying thousands and millions of SNP loci useful
Davide Bianchi, Lucio Brancadoro, Gabriella De Lorenzis   +2 more
doaj   +1 more source

Sequence-based genotyping for marker discovery and co-dominant scoring in germplasm and populations.

PLoS ONE, 2012
Conventional marker-based genotyping platforms are widely available, but not without their limitations. In this context, we developed Sequence-Based Genotyping (SBG), a technology for simultaneous marker discovery and co-dominant scoring, using next ...
Hoa T Truong, A Marcos Ramos, Feyruz Yalcin, Marjo de Ruiter, Hein J A van der Poel, Koen H J Huvenaars, René C J Hogers, Leonora J G van Enckevort, Antoine Janssen, Nathalie J van Orsouw, Michiel J T van Eijk   +10 more
doaj   +1 more source

Inference of kinship coefficients from Korean SNP genotyping data [PDF]

BMB Reports, 2013
The determination of relatedness between individuals in afamily is crucial in analysis of common complex diseases. Wepresent a method to infer close inter-familial relationshipsbased on SNP genotyping data and provide the relationshipcoefficient of ...
Seong-Jin Park, Jin Ok Yang, Sang Cheol Kim, Jekeun Kwon, Sanghyuk Lee, Byungwook Lee   +5 more
doaj   +1 more source

Reference-free SNP calling: improved accuracy by preventing incorrect calls from repetitive genomic regions

Biology Direct, 2012
Background Single nucleotide polymorphisms (SNPs) are the most abundant type of genetic variation in eukaryotic genomes and have recently become the marker of choice in a wide variety of ecological and evolutionary studies.
Dou Jinzhuang, Zhao Xiqiang, Fu Xiaoteng, Jiao Wenqian, Wang Nannan, Zhang Lingling, Hu Xiaoli, Wang Shi, Bao Zhenmin   +8 more
doaj   +1 more source

Comparison of TaqMan, KASP and rhAmp SNP genotyping platforms in hexaploid wheat.

PLoS ONE, 2019
Advances in high-throughput genotyping enable the generation of genome-scale data much more easily and at lower cost than ever before. However, small-scale and cost-effective high-throughput single-nucleotide polymorphism (SNP) genotyping technologies ...
Habtamu Ayalew, Pak Wah Tsang, Chenggen Chu, Junzhou Wang, Shuyu Liu, Caifu Chen, Xue-Feng Ma   +6 more
doaj   +1 more source

High-throughput genotyping of single nucleotide polymorphisms with rolling circle amplification

BMC Genomics, 2001
Background Single nucleotide polymorphisms (SNPs) are the foundation of powerful complex trait and pharmacogenomic analyses. The availability of large SNP databases, however, has emphasized a need for inexpensive SNP genotyping methods of commensurate ...
Sun Zhenyu, Zong Qiuling, Grimwade Brian, Kumar Gyanendra, Bandaru Rajanikanta, Alsmadi Osama, Dean Frank B, Driscoll Mark D, Hosono Seiyu, Faruqi A Fawad, Du Yuefen, Kingsmore Stephen, Knott Tim, Lasken Roger S   +13 more
doaj   +1 more source