Results 41 to 50 of about 97,365 (285)

Comparison of sequencing-based and array-based genotyping platforms for genomic prediction of maize hybrid performance

open access: yesCrop Journal, 2023
Genomic selection (GS) is a powerful tool for improving genetic gain in maize breeding. However, its routine application in large-scale breeding pipelines is limited by the high cost of genotyping platforms.
Guangning Yu   +12 more
doaj  

Reference-free SNP calling: improved accuracy by preventing incorrect calls from repetitive genomic regions

open access: yesBiology Direct, 2012
Background Single nucleotide polymorphisms (SNPs) are the most abundant type of genetic variation in eukaryotic genomes and have recently become the marker of choice in a wide variety of ecological and evolutionary studies.
Dou Jinzhuang   +8 more
doaj   +1 more source

Genotyping of SNPs in a Polyploid Genome by Pyrosequencing™ [PDF]

open access: yesBioTechniques, 2002
Single-nucleotide polymorphisms (SNPs) are the most frequent DNA sequence variations, and they have become increasingly popular markers for association studies. Allelic discrimination of the mostly binary SNPs has been reported for diploid species, mainly the human, but not for polyploid genomes such as the agriculturally important crops.
Christiane Gebhardt   +3 more
openaire   +4 more sources

Sequence-based genotyping for marker discovery and co-dominant scoring in germplasm and populations.

open access: yesPLoS ONE, 2012
Conventional marker-based genotyping platforms are widely available, but not without their limitations. In this context, we developed Sequence-Based Genotyping (SBG), a technology for simultaneous marker discovery and co-dominant scoring, using next ...
Hoa T Truong   +10 more
doaj   +1 more source

Inference of kinship coefficients from Korean SNP genotyping data [PDF]

open access: yesBMB Reports, 2013
The determination of relatedness between individuals in afamily is crucial in analysis of common complex diseases. Wepresent a method to infer close inter-familial relationshipsbased on SNP genotyping data and provide the relationshipcoefficient of ...
Seong-Jin Park   +5 more
doaj   +1 more source

Methods for Scarless, Selection-Free Generation of Human Cells and Allele-Specific Functional Analysis of Disease-Associated SNPs and Variants of Uncertain Significance. [PDF]

open access: yes, 2017
With the continued emergence of risk loci from Genome-Wide Association studies and variants of uncertain significance identified from patient sequencing, better methods are required to translate these human genetic findings into improvements in public ...
Carvajal-Carmona, Luis G   +4 more
core   +4 more sources

Conflicting Results in SNP Genotype Assessment

open access: yesBioTechniques, 2007
Single nucleotide polymorphisms (SNPs) are highly abundant in the genome and especially useful in the search for disease susceptibility genes via population-based association or linkage studies. Therefore, there is a strong need for high throughput and reliable methodologies to assess the SNP genotypes. Despite an unambiguous result of an SNP analysis,
Hansen, Lise Lotte   +3 more
openaire   +5 more sources

Detecting SARS-CoV-2 variants with SNP genotyping.

open access: yesPLoS ONE, 2021
Tracking genetic variations from positive SARS-CoV-2 samples yields crucial information about the number of variants circulating in an outbreak and the possible lines of transmission but sequencing every positive SARS-CoV-2 sample would be prohibitively ...
Helen Harper   +11 more
doaj   +1 more source

Clinical application of high throughput molecular screening techniques for pharmacogenomics. [PDF]

open access: yes, 2011
Genetic analysis is one of the fastest-growing areas of clinical diagnostics. Fortunately, as our knowledge of clinically relevant genetic variants rapidly expands, so does our ability to detect these variants in patient samples.
Schrijver, Iris, Wiita, Arun P
core   +1 more source

The genetic basis of host preference and resting behavior in the major African malaria vector, Anopheles arabiensis [PDF]

open access: yes, 2016
Malaria transmission is dependent on the propensity of Anopheles mosquitoes to bite humans (anthropophily) instead of other dead end hosts. Recent increases in the usage of Long Lasting Insecticide Treated Nets (LLINs) in Africa have been associated ...
Collier, T. J.   +12 more
core   +12 more sources

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