Results 41 to 50 of about 223,459 (323)

Joint Haplotype Assembly and Genotype Calling via Sequential Monte Carlo Algorithm [PDF]

, 2015
Genetic variations predispose individuals to hereditary diseases, play important role in the development of complex diseases, and impact drug metabolism. The full information about the DNA variations in the genome of an individual is given by haplotypes,
Ahn, Soyeon, Vikalo, Haris
core   +3 more sources

Toward genome-wide SNP genotyping [PDF]

Nature Genetics, 2005
Genome-wide association studies with SNP markers are expected to allow identification of genes that underlie complex disorders. Hundreds of thousands of SNP markers will be required for comprehensive genome-wide association studies. The development of microarray-based methods for SNP genotyping on this scale remains a demanding task, despite many ...
openaire   +2 more sources

Sequence-based genotyping for marker discovery and co-dominant scoring in germplasm and populations.

PLoS ONE, 2012
Conventional marker-based genotyping platforms are widely available, but not without their limitations. In this context, we developed Sequence-Based Genotyping (SBG), a technology for simultaneous marker discovery and co-dominant scoring, using next ...
Hoa T Truong, A Marcos Ramos, Feyruz Yalcin, Marjo de Ruiter, Hein J A van der Poel, Koen H J Huvenaars, René C J Hogers, Leonora J G van Enckevort, Antoine Janssen, Nathalie J van Orsouw, Michiel J T van Eijk   +10 more
doaj   +1 more source

Narrowing the wingless-2 mutation to a 227 kb candidate region on chicken chromosome 12. [PDF]

, 2018
Wingless-2 (wg-2) is an autosomal recessive mutation in chicken that results in an embryonic lethal condition. Affected individuals exhibit a multisystem syndrome characterized by absent wings, truncated legs, and craniofacial, kidney, and feather ...
Cheng, HH, Delany, ME, Gitter, CL, Kaya, M, May, B, O'Hare, EA, Webb, AE, Youngworth, IA   +7 more
core   +1 more source

Genomic Analysis Using Bayesian Methods under Different Genotyping Platforms in Korean Duroc Pigs

Animals, 2020
Genomic evaluation has been widely applied to several species using commercial single nucleotide polymorphism (SNP) genotyping platforms. This study investigated the informative genomic regions and the efficiency of genomic prediction by using two ...
Jungjae Lee, Yongmin Kim, Eunseok Cho, Kyuho Cho, Soojin Sa, Youngsin Kim, Jungwoo Choi, Jinsoo Kim, Junki Hong, Taejeong Choi   +9 more
doaj   +1 more source

Conflicting Results in SNP Genotype Assessment

BioTechniques, 2007
Single nucleotide polymorphisms (SNPs) are highly abundant in the genome and especially useful in the search for disease susceptibility genes via population-based association or linkage studies. Therefore, there is a strong need for high throughput and reliable methodologies to assess the SNP genotypes. Despite an unambiguous result of an SNP analysis,
Hansen, Lise Lotte, Madsen, Bo Eskerod, Pedersen, Kristina, Wiuf, Carsten   +3 more
openaire   +4 more sources

Comparison of TaqMan, KASP and rhAmp SNP genotyping platforms in hexaploid wheat.

PLoS ONE, 2019
Advances in high-throughput genotyping enable the generation of genome-scale data much more easily and at lower cost than ever before. However, small-scale and cost-effective high-throughput single-nucleotide polymorphism (SNP) genotyping technologies ...
Habtamu Ayalew, Pak Wah Tsang, Chenggen Chu, Junzhou Wang, Shuyu Liu, Caifu Chen, Xue-Feng Ma   +6 more
doaj   +1 more source

High-throughput genotyping of single nucleotide polymorphisms with rolling circle amplification

BMC Genomics, 2001
Background Single nucleotide polymorphisms (SNPs) are the foundation of powerful complex trait and pharmacogenomic analyses. The availability of large SNP databases, however, has emphasized a need for inexpensive SNP genotyping methods of commensurate ...
Sun Zhenyu, Zong Qiuling, Grimwade Brian, Kumar Gyanendra, Bandaru Rajanikanta, Alsmadi Osama, Dean Frank B, Driscoll Mark D, Hosono Seiyu, Faruqi A Fawad, Du Yuefen, Kingsmore Stephen, Knott Tim, Lasken Roger S   +13 more
doaj   +1 more source

Whole genome SNP genotype piecemeal imputation [PDF]

BMC Bioinformatics, 2015
Background Despite ongoing reductions in the cost of sequencing technologies, whole genome SNP genotype imputation is often used as an alternative for obtaining abundant SNP genotypes for genome wide association studies. Several existing genotype imputation methods can be efficient for this purpose, while achieving various levels of imputation accuracy.
Stothard, Paul, Wang, Yining, Lin, Guohui, Wylie, Tim   +3 more
openaire   +3 more sources

Novel Design of Imputation-Enabled SNP Arrays for Breeding and Research Applications Supporting Multi-Species Hybridization

Frontiers in Plant Science, 2021
Array-based single nucleotide polymorphism (SNP) genotyping platforms have low genotype error and missing data rates compared to genotyping-by-sequencing technologies.
Gabriel Keeble-Gagnère, Raj Pasam, Kerrie L. Forrest, Debbie Wong, Hannah Robinson, Jayfred Godoy, Allan Rattey, David Moody, Daniel Mullan, Tresslyn Walmsley, Hans D. Daetwyler, Hans D. Daetwyler, Josquin Tibbits, Matthew J. Hayden, Matthew J. Hayden   +14 more
doaj   +1 more source