Results 51 to 60 of about 215,087 (323)

Genomic Analysis Using Bayesian Methods under Different Genotyping Platforms in Korean Duroc Pigs

Animals, 2020
Genomic evaluation has been widely applied to several species using commercial single nucleotide polymorphism (SNP) genotyping platforms. This study investigated the informative genomic regions and the efficiency of genomic prediction by using two ...
Jungjae Lee, Yongmin Kim, Eunseok Cho, Kyuho Cho, Soojin Sa, Youngsin Kim, Jungwoo Choi, Jinsoo Kim, Junki Hong, Taejeong Choi   +9 more
doaj   +1 more source

Using GWAS Data to Identify Copy Number Variants Contributing to Common Complex Diseases

, 2010
Copy number variants (CNVs) account for more polymorphic base pairs in the human genome than do single nucleotide polymorphisms (SNPs). CNVs encompass genes as well as noncoding DNA, making these polymorphisms good candidates for functional variation ...
Teslovich, Tanya M., Zöllner, Sebastian
core   +1 more source

Narrowing the wingless-2 mutation to a 227 kb candidate region on chicken chromosome 12. [PDF]

, 2018
Wingless-2 (wg-2) is an autosomal recessive mutation in chicken that results in an embryonic lethal condition. Affected individuals exhibit a multisystem syndrome characterized by absent wings, truncated legs, and craniofacial, kidney, and feather ...
Cheng, HH, Delany, ME, Gitter, CL, Kaya, M, May, B, O'Hare, EA, Webb, AE, Youngworth, IA   +7 more
core   +1 more source

Novel Design of Imputation-Enabled SNP Arrays for Breeding and Research Applications Supporting Multi-Species Hybridization

Frontiers in Plant Science, 2021
Array-based single nucleotide polymorphism (SNP) genotyping platforms have low genotype error and missing data rates compared to genotyping-by-sequencing technologies.
Gabriel Keeble-Gagnère, Raj Pasam, Kerrie L. Forrest, Debbie Wong, Hannah Robinson, Jayfred Godoy, Allan Rattey, David Moody, Daniel Mullan, Tresslyn Walmsley, Hans D. Daetwyler, Hans D. Daetwyler, Josquin Tibbits, Matthew J. Hayden, Matthew J. Hayden   +14 more
doaj   +1 more source

An integrated molecular and conventional breeding scheme for enhancing genetic gain in maize in Africa [PDF]

, 2020
Open Access Journal; Published online: 06 Nov 2019Maize production in West and Central Africa (WCA) is constrained by a wide range of interacting stresses that keep productivity below potential yields.
Gedil, M., Menkir, A.
core   +1 more source

Genotyping and annotation of Affymetrix SNP arrays

Nucleic Acids Research, 2006
In this paper we develop a new method for genotyping Affymetrix single nucleotide polymorphism (SNP) array. The method is based on (i) using multiple arrays at the same time to determine the genotypes and (ii) a model that relates intensities of individual SNPs to each other.
Carsten Wiuf, Carsten Wiuf, Claus L. Andersen, Philippe Lamy, Friedrik P. Wikman   +4 more
openaire   +3 more sources

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Development and Applications of a High Throughput Genotyping Tool for Polyploid Crops: Single Nucleotide Polymorphism (SNP) Array

Frontiers in Plant Science, 2018
Polypoid species play significant roles in agriculture and food production. Many crop species are polyploid, such as potato, wheat, strawberry, and sugarcane.
Qian You, Qian You, Xiping Yang, Ze Peng, Liping Xu, Jianping Wang, Jianping Wang, Jianping Wang   +7 more
doaj   +1 more source

On the trail of SNPs [PDF]

Nature, 2003
Extracting useful data from the human genome sequence is a major challenge. Lisa Melton examines the early steps towards personal genotyping.
openaire   +2 more sources

Cognitive Resilience in Apolipoprotein ε4 Carrier Women Predicted by Neuron‐Derived Extracellular Vesicles

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The Apolipoprotein (APOE) ε4 allele is the strongest genetic risk factor for late‐onset Alzheimer's disease (AD); however, many ε4 carriers remain cognitively intact into old age. Leveraging plasma neuron‐derived extracellular vesicles (NDEVs), we sought to identify biomarkers of cognitive resilience and their interplay with APOE ...
Apostolos Manolopoulos, Maja Mustapic, Carlos Nogueras‐Ortiz, Francheska Delgado‐Peraza, Krishna A. Pucha, Pamela J. Yao, Joseph Blommer, Michael P. Vreones, William York, De' Larrian Knight, Stephen R. Rapp, Aladdin H. Shadyab, JoAnn E. Manson, Ramon Casanova, Robert B. Wallace, Luigi Ferrucci, Susan M. Resnick, Dimitrios Kapogiannis   +17 more
wiley   +1 more source