Results 1 to 10 of about 526,115 (127)

Strong signature of natural selection within an FHIT intron implicated in prostate cancer risk [PDF]

, 2008
Previously, a candidate gene linkage approach on brother pairs affected with prostate cancer identified a locus of prostate cancer susceptibility at D3S1234 within the fragile histidine triad gene (FHIT), a tumor suppressor that induces apoptosis ...
A Auton, A Esquela-Kerscher, A Fischer, A Latil, A Vecchione, Al B. Benson, AM Adams, AM Levin, Cathryn Lundberg, CC Spencer, Ching Ouyang, D Charlesworth, D Gordon, DA Nickerson, David Johnson, DJ Schaid, E Dudbridge, EM Reis, ET Dermitzakis, F Tajima, FM De La Vega, G Sozzi, G Thomas, Garrett Larson, GP Larson, Guillermo Rivas, HH Nelson, J Gudmundsson, J Gudmundsson, J Gudmundsson, James A. Stewart, JC Barrett, JC Fay, Jeffrey Weitzel, Jerry Slater, JM Bland, John Archambeau, John M. Kirkwood, JS Pedersen, JS Rhim, K Huebner, K Preacher, Louis Geller, M Bamshad, M Nei, M Stephens, M Stephens, M Yeager, Magnus Nordborg, Mary B. Daly, Matthew W. Hahn, N Yu, NA Becker, P Kapranov, Peter J. O'Dwyer, PI Lin, RA Eeles, Rebecca Sutphen, RL Fouts, RR Hudson, S Wooding, SB Gabriel, T Bersaglieri, Theodore G. Krontiris, V Chizhikov, Yan Ding, YX Fu, Z Guo   +67 more
core   +29 more sources

GENETIC VARIATION IN HOST IMMUNE RESPONSE TO MAJOR INFECTIOUS DISEASES IN BOVINES AND ITS APPLICATION IN ANIMAL BREEDING : A REVIEW [PDF]

Exploratory Animal and Medical Research, 2023
Livestock infectious diseases pose a significant threat to animal health and welfare on a worldwide scale, and efficient management of these diseases is essential for maintaining agronomic health, securing national and international food supply, and ...
Chhaya Rani, Anuj Chauhan, Indrasen Chauhan, Sakshi Vaishnav, Argana Ajay, Tapendra Saini , Snehasmita Panda , G. K Gaur , Bharat Bhushan   +8 more
doaj   +1 more source

Genetic correlates of longevity and selected age-related phenotypes: a genome-wide association study in the Framingham Study [PDF]

, 2007
BACKGROUND: Family studies and heritability estimates provide evidence for a genetic contribution to variation in the human life span. METHODS:We conducted a genome wide association study (Affymetrix 100K SNP GeneChip) for longevity-related traits in a ...
Benjamin, Emelia J, D'Agostino, Ralph B, Govindaraju, Raju, Guo, Chao-Yu, Karasik, David, Kelly-Hayes, Margaret, Kiel, Douglas P, Lunetta, Kathryn L, Massaro, Joseph M, Murabito, Joanne M, Pencina, Michael J, Seshadri, Sudha   +11 more
core   +14 more sources

Serum 25-hydroxyvitamin D levels and the risk of non-alcoholic fatty liver: A two-sample Mendelian randomization study

The Saudi Journal of Gastroenterology, 2023
Background: Accumulated studies have shown that low expression of 25-hydroxyvitamin D [25(OH)D] was significantly associated with the risk of non-alcoholic fatty liver disease (NAFLD). However, the exact causality is still unknown.
Qi Sheng, Huanchen Shi, Shousheng Liu, Likun Zhuang, Zhenzhen Zhao, Yongning Xin   +5 more
doaj   +1 more source

Impact of a Single Nucleotide Polymorphism on the 3D Protein Structure and Ubiquitination Activity of E3 Ubiquitin Ligase Arkadia

Frontiers in Molecular Biosciences, 2022
Single nucleotide polymorphisms (SNPs) are genetic variations which can play a vital role in the study of human health. SNP studies are often used to identify point mutations that are associated with diseases.
Maria Birkou, Vasilios Raptis, Konstantinos D. Marousis, Athanasios Tsevis, Kyriakos Bourikas, Detlef Bentrop, Vasso Episkopou, Georgios A. Spyroulias   +7 more
doaj   +1 more source

Significance of the Estrogen Hormone and Single Nucleotide Polymorphisms in the Progression of Breast Cancer among Female [PDF]

Archives of Razi Institute, 2022
Breast cancer is one of the most frequent types of malignancies among women and is internationally recognized as the main reason for cancer-caused mortality.
A Mohammed Alwan, J Tavakol Afshari, F Afzaljavan   +2 more
doaj   +1 more source

Range-wide parallel climate-associated genomic clines in Atlantic salmon [PDF]

Royal Society Open Science, 2017
Clinal variation across replicated environmental gradients can reveal evidence of local adaptation, providing insight into the demographic and evolutionary processes that shape intraspecific diversity.
Nicholas W. Jeffery, Ryan R. E. Stanley, Brendan F. Wringe, Javier Guijarro-Sabaniel, Vincent Bourret, Louis Bernatchez, Paul Bentzen, Robert G. Beiko, John Gilbey, Marie Clément, Ian R. Bradbury   +10 more
doaj   +1 more source

Genome-wide association mapping and genomic prediction for late blight and potato cyst nematode resistance in potato (Solanum tuberosum L.)

Frontiers in Plant Science, 2023
Potatoes are an important source of food for millions of people worldwide. Biotic stresses, notably late blight and potato cyst nematodes (PCN) pose a major threat to potato production worldwide, and knowledge of genes controlling these traits is limited.
Salej Sood, Vinay Bhardwaj, Aarti Bairwa, Dalamu, Sanjeev Sharma, Ashwani K. Sharma, Ashwani Kumar, Mehi Lal, Vinod Kumar   +8 more
doaj   +1 more source

Developing Single Nucleotide Polymorphisms for Identification of Cod Products by RAD-Seq

Animals, 2020
The increase in the rate of seafood fraud, particularly in the expensive fishes, forces us to verify the identity of marine products. Meanwhile, the definition of cod lacks consistency at the international level, as few standards and effective ...
Shoujia Jiang, Xingyu Ma, Tao Li, Changqing Zhu, Xinxin You   +4 more
doaj   +1 more source

Low-density genotype panel for both parentage verification and discovery in a multi-breed sheep population [PDF]

, 2019
peer-reviewedThe generally low usage of artificial insemination and single-sire mating in sheep, compounded by mob lambing (and lambing outdoors), implies that parentage assignment in sheep is challenging.
Berry, Donagh, McDermott, K., McHugh, Noirin, O’Brien, A.C., Wall, E.   +4 more
core   +1 more source