Results 21 to 30 of about 524,252 (269)
Background: Lung cancer is one of the most serious malignant tumors endangering human health and life. This study focused on evaluating the association between single nucleotide polymorphisms (SNPs) of the glutaminase (GLS) and lung cancer susceptibility
Yuhe Wang +8 more
doaj +1 more source
A genetic variation map for chicken with 2.8 million single-nucleotide polymorphisms [PDF]
We describe a genetic variation map for the chicken genome containing 2.8 million single-nucleotide polymorphisms ( SNPs). This map is based on a comparison of the sequences of three domestic chicken breeds ( a broiler, a layer and a Chinese silkie) with
Aerts, Andrea +114 more
core +3 more sources
The papers published in this Special Issue “SNP arrays” (Single Nucleotide Polymorphism Arrays) focus on several perspectives associated with arrays of this type. The range of papers vary from a case report to reviews, thereby targeting wider audiences working in this field. The research focus of SNP arrays is often human cancers but this Issue expands
openaire +2 more sources
Background: Environmental effects and personal experiences could be expressed in individuals through epigenetic non-structural changes such as DNA methylation. This methylation could up- regulate or down-regulate corresponding gene expressions and modify
Yvon eChagnon +3 more
doaj +1 more source
GENETIC VARIATION IN HOST IMMUNE RESPONSE TO MAJOR INFECTIOUS DISEASES IN BOVINES AND ITS APPLICATION IN ANIMAL BREEDING : A REVIEW [PDF]
Livestock infectious diseases pose a significant threat to animal health and welfare on a worldwide scale, and efficient management of these diseases is essential for maintaining agronomic health, securing national and international food supply, and ...
Chhaya Rani +8 more
doaj +1 more source
Genetic Variation in FADS Genes and Plasma Cholesterol Levels in 2-Year-Old Infants [PDF]
Single nucleotide polymorphisms (SNPs) in genes involved in fatty acid metabolism (FADS1 FADS2 gene cluster) are associated with plasma lipid levels. We aimed to investigate whether these associations are already present early in life and compare the ...
Heinrich, Joachim +10 more
core +1 more source
SNP interaction pattern identifier (SIPI): an intensive search for SNP–SNP interaction patterns [PDF]
Abstract Motivation Testing SNP–SNP interactions is considered as a key for overcoming bottlenecks of genetic association studies. However, related statistical methods for testing SNP–SNP interactions are underdeveloped.
Lin, Hui-Yi +41 more
openaire +6 more sources
SNP Miniplexes for Individual Identification of Random-Bred Domestic Cats. [PDF]
Phenotypic and genotypic characteristics of the cat can be obtained from single nucleotide polymorphisms (SNPs) analyses of fur. This study developed miniplexes using SNPs with high discriminating power for random-bred domestic cats, focusing on ...
Brooks, Ashley +5 more
core +2 more sources
ErbB polymorphisms: Insights and implications for response to targeted cancer therapeutics
Advances in high-throughput genomic-scanning have expanded the repertory of genetic variations in DNA sequences encoding ErbB tyrosine kinase receptors in humans, including single nucleotide polymorphisms (SNPs), polymorphic repetitive elements ...
Moulay A Alaoui-Jamali +2 more
doaj +1 more source
SKM-SNP: SNP markers detection method
SKM-SNP, SNP markers detection program, is proposed to identify a set of relevant SNPs for the association between a disease and multiple marker genotypes. We employ a subspace categorical clustering algorithm to compute a weight for each SNP in the group of patient samples and the group of normal samples, and use the weights to identify the subsets of
Liu, Y +4 more
openaire +4 more sources

