Results 101 to 110 of about 17,437 (131)

Cell-Type Specificity of Mosaic Chromosome 1q Gain Resolved by snRNA-seq in a Case of Epilepsy With Hyaline Protoplasmic Astrocytopathy. [PDF]

Neurol Genet
Leng K, Cadwell CR, Devine WP, Tihan T, Qi Z, Singhal NS, Glenn OA, Kamiya S, Wiita AP, Berger AC, Shieh JT, Titus EW, Paredes MF, Upadhyay V.   +13 more
europepmc   +1 more source

Increased [¹⁸F]FDG uptake in the infarcted myocardial area displayed by combined PET/CMR correlates with snRNA-seq-detected inflammatory cell invasion. [PDF]

Basic Res Cardiol
Lukovic D, Gyöngyösi M, Pavo IJ, Mester-Tonczar J, Einzinger P, Zlabinger K, Kastner N, Spannbauer A, Traxler D, Pavo N, Goliasch G, Pils D, Jakab A, Szankai Z, Michel-Behnke I, Zhang L, Devaux Y, Graf S, Beitzke D, Winkler J.   +19 more
europepmc   +1 more source

snRNA-seq of human cutaneous neurofibromas before and after selumetinib treatment implicates role of altered Schwann cell states, inter-cellular signaling, and extracellular matrix in treatment response. [PDF]

Acta Neuropathol Commun
Church C, Fay CX, Kriukov E, Liu H, Cannon A, Baldwin LA, Crossman DK, Korf B, Wallace MR, Gross AM, Widemann BC, Kesterson RA, Baranov P, Wallis D.   +13 more
europepmc   +1 more source

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Hemocyte Nuclei Isolation from Adult Drosophila melanogaster for snRNA-seq

Methods in Molecular Biology, 2023
In adult Drosophila, most of the hemocytes are macrophage-like cells (so called plasmatocytes), which serve various functions in organ homeostasis and immune defense. Ontogeny and functions are largely conserved between vertebrate and invertebrate macrophages.
Katrin Kierdorf, Katrin Paeschke, Fabian Hersperger   +2 more
exaly   +4 more sources

snRNA-seq reveals a subpopulation of adipocytes that regulates thermogenesis

Nature, 2020
Adipose tissue is usually classified on the basis of its function as white, brown or beige (brite)1. It is an important regulator of systemic metabolism, as shown by the fact that dysfunctional adipose tissue in obesity leads to a variety of secondary metabolic complications2,3.
Wenfei Sun, Lucia Balazova, Jozef Ukropec   +2 more
exaly   +5 more sources

snRNA-seq stratifies multiple sclerosis patients into distinct white matter glial responses [PDF]

Neuron
Poor understanding of the cellular and molecular basis of clinical and genetic heterogeneity in progressive multiple sclerosis (MS) has hindered the search for new effective therapies. To address this gap, we analyzed 632,000 single-nucleus RNA sequencing profiles from 156 brain tissue samples of MS and control donors to examine inter- and intra-donor ...
Anna Williams, Daniela Calini
exaly   +6 more sources

snRNA-seq of mouse brain cortex

2023
GDF11 loxp mice aged 4-5M were treated in the prefrontal lobe with a focal injection of AAV9 CaMKIIa-Cre-P2A-GFP virus (KO group) or AAV9 CaMKIIa-GFP virus (Ctrl group). We used single nucleus RNA sequencing (snRNA-seq) to analyze the differential expressed genes (DEGs).
openaire   +1 more source

snRNA-seq of Cervical Squamous Cell Carcinoma

2022
To understand the etiological, structural, and immunological characteristics of cervical squamous cell carcinoma (CSCC), we conducted single nucleus RNA sequencing (snRNA-seq) experiments for cervical samples from 5 ...
openaire   +1 more source